Gu, Chuanjia Yuan, Haibin Yang, Chi Xie, Fangfang Chen, Junxiang Zhu, Lei Jiang, Yifeng Sun, Jiayuan
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Thorax
Transbronchial cryoablation shows potential as a local therapy for inoperable peripheral lung cancer. However, its clinical application for peripheral pulmonary lesions has not been reported yet. An improved cryoprobe with an 8-mm-long, 1.9-mm-wide cryotip was used. Initially, the safety and effectiveness of this cryoprobe were assessed in an in vi...
Williams, Parris J Philip, Keir E J Buttery, Sara C Perkins, Alexis Chan, Ley Bartlett, Emily C Devaraj, Anand Kemp, Samuel V Addis, James Derbyshire, Jane
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Thorax
Immediate smoking cessation interventions delivered alongside targeted lung health checks (TLHCs) to screen for lung cancer increase self-reported abstinence at 3 months. The impact on longer term, objectively confirmed quit rates remains to be established. We followed up participants from two clinical trials in people aged 55-75 years who smoked a...
Koo, Minjoung Monica Mounce, Luke T A Rafiq, Meena Callister, Matthew E J Singh, Hardeep Abel, Gary A Lyratzopoulos, Georgios
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Thorax
Guidelines recommend urgent chest X-ray for newly presenting dyspnoea or haemoptysis but there is little evidence about their implementation. We analysed linked primary care and hospital imaging data for patients aged 30+ years newly presenting with dyspnoea or haemoptysis in primary care during April 2012 to March 2017. We examined guideline-conco...
Whittaker, Hannah Rothnie, Kieran J Quint, Jennifer K
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Thorax
Identifying correlates of cause-specific mortality in patients with chronic obstructive pulmonary disease (COPD) may aid the targeting of therapies to reduce mortality. We determined factors associated with causes of death in a primary care COPD population. Clinical Practice Research Datalink Aurum was linked to Hospital Episode Statistics and deat...
Khalaf, Zainab Bush, Andrew Saglani, Sejal Bloom, Chloe I
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Thorax
Asthma trials and guidelines often do not distinguish between adolescents and younger children. Using a large English data set, we evaluated the impact of age on asthma characteristics, management and exacerbations. Primary care medical records, 2004-2021, were linked to hospital records. Children were categorised by age at diagnosis and followed u...
McLarty, Joshua Litton, Edward Beane, Abigail Aryal, Diptesh Bailey, Michael Bendel, Stepani Burghi, Gaston Christensen, Steffen Christiansen, Christian Fynbo Dongelmans, Dave A
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Thorax
The COVID-19 pandemic resulted in a large number of critical care admissions. While national reports have described the outcomes of patients with COVID-19, there is limited international data of the pandemic impact on non-COVID-19 patients requiring intensive care treatment. We conducted an international, retrospective cohort study using 2019 and 2...
Mathavan, Akshay Mathavan, Akash Witten, Cordelia Ataya, Ali
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Thorax
Busby, John McDowell, P Jane Pfeffer, Paul E Mansur, Adel Hasan Heaney, Liam G
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Thorax
Ethnic disparities exist within asthma; however, country of birth is rarely investigated. We described demographic and clinical characteristics by ethnicity and country of birth within the UK Biobank. Lung function and asthma hospitalisations were similar for white, black and North-East Asian participants, however, South-East (SE) Asians more commo...
Tackett, Alayna P Urman, Robert Barrington-Trimis, Jessica Liu, Feifei Hong, Hanna Pentz, Mary Ann Islam, Talat S Eckel, Sandrah P Rebuli, Meghan Leventhal, Adam
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Thorax
Electronic cigarette (e-cigarette) aerosol contains volatile aldehydes, including flavourings and oxidant metals with known pulmonary toxicity. To evaluate the associations of e-cigarette use with symptoms of wheeze, bronchitic symptoms and shortness of breath (SOB) across 4 years of prospective data. Participants completed questionnaires on respir...
Russell, James A
Published in
Thorax
