Isolated conjugated hyperbilirubinemia with rifampicin and cross-reaction with rifabutin: A drug-endogenous substance in...
Published in Therapie
Pulmonary toxicity of mTOR inhibitors. Comparisons of two populations: Solid organ recipients and cancer patients.
Published in Therapie
Mammalian target of rapamycin (mTOR) inhibitors-associated pneumonitis (mTOR-IP) has long been described in solid organ recipients (T) patients but more recently in cancer (K) patients. Its overall characteristics have never been compared between these 2 populations. The aim of this study was to compare them in terms of presentation, severity and o...
Reality of drug-induced erythema multiforme: A French pharmacovigilance study.
Published in Therapie
Since the 2002 SCAR study, erythema multiforme (EM), a post-infectious disease, has been distinguished from Stevens-Johnson syndrome (SJS), drug-induced. Nevertheless, EM cases are still reported in the French pharmacovigilance database (FPDB). To describe EM reported in the FPDB and to compare the quality and the characteristics of the reports. Th...
Overview of literature monitoring practice of clinical trials vigilance units in French institutional sponsors - A study...
...Published in Therapie
The evaluation of clinical trial (CT) safety is the main task of CT vigilance units. In addition to the management of adverse events, the units must review the literature to identify information that may impact the benefit-risk assessment of studies. In this survey, we investigated the literature monitoring (LM) activity of French Institutional Vig...
Alprazolam misuse: Analysis of French Addictovigilance Network data from 2011 to 2020.
...Published in Therapie
Alprazolam, a high-potency and short-acting anxiolytic benzodiazepine, is one of the most misused benzodiazepines in France. In the context of various reports on alprazolam misuse during the COVID-19 pandemic, the objective of this study was to assess alprazolam abuse potential by analyzing French addictovigilance and international data. Data colle...
Pharmacoepidemiology and public decision.
Published in Therapie
Impact of diabetes mellitus on rifampicin's plasma concentration and bioavailability in patients with tuberculosis: A sy...
Published in Therapie
To assess the impact of diabetes mellitus on plasma concentration and bioavailability of rifampicin. Web of Science, Cochrane Library, PubMed and Scopus databases were screened until September 2020 on studies reported rifampicin's plasma concentration, bioavailability among diabetic tuberculosis patients and non-diabetic tuberculosis patients. Acco...
[Climate crisis as a powerful argument to improve conflicts of interest statement].
Published in Therapie
Cardiac arrests associated with low plasma and tissue levels of local anaesthetics.
...Published in Therapie
Impact of the COVID-19 pandemic on antiviral drug development for other community-acquired respiratory viruses' infectio...
Published in Therapie
The coronavirus disease 2019 (COVID-19) pandemic indirectly resulted in missed therapeutic opportunities for many diseases. Here we focus on community-acquired respiratory viruses other than severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) [respiratory syncytial virus, parainfluenza and influenza A], and highlight the pandemics impact on...
