Locoregional infusion of IL13Rα2-specific immunotoxins in children and adults with high-grade glioma.
Published in Therapeutic delivery
SARS-CoV-2: vaccinology and emerging therapeutics; challenges and future developments
Published in Therapeutic Delivery
As SARS-CoV-2 emerge, variants such as Omicron (B.1.1.529), Delta (B.1.617.2), and those from the United Kingdom (B.1.1.7), South Africa (B.1.351), Brazil (P.1) and India (B.1.6.17 lineage) have raised concerns of the reduced neutralising ability of antibodies and increased ability to evade the current six approved COVID-19 vaccine candidates. This...
The latest developments in the area of therapeutic delivery excluding some diseases, such as COVID-19 and the big three ...
Published in Therapeutic delivery
It is the beginning of a new decade, where COVID-19 and the 'big three' (HIV/AID, malaria and tuberculosis) have raised public awareness of the type of challenges researchers face every day. Beyond these diseases, there are also still many more for which scientists are working to develop new therapies and their impact in healthcare is enormous too....
Antiviral monoclonal antibody cocktails as a modern weapon in combating pandemics
Published in Therapeutic Delivery
An overview of vaccine development for COVID-19
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Published in Therapeutic Delivery
The COVID-19 pandemic continues to endanger world health and the economy. The causative SARS-CoV-2 coronavirus has a unique replication system. The end point of the COVID-19 pandemic is either herd immunity or widespread availability of an effective vaccine. Multiple candidate vaccines – peptide, virus-like particle, viral vectors (replicating and ...
Therapeutic potential of inhalable medications to combat coronavirus disease-2019.
Published in Therapeutic delivery
Review of the Omnipod® 5 Automated Glucose Control System Powered by Horizon™ for the treatment of Type 1 diabetes.
Published in Therapeutic delivery
Type 1 diabetes (T1D) is a medical condition that requires constant management, including monitoring of blood glucose levels and administration of insulin. Advancements in diabetes technology have offered methods to reduce the burden on people with T1D. Several hybrid closed-loop systems are commercially available or in clinical trials, each with u...
The potential role of nanomedicine on COVID-19 therapeutics.
Published in Therapeutic delivery
Sustained acoustic medicine; sonophoresis for nonsteroidal anti-inflammatory drug delivery in arthritis.
Published in Therapeutic delivery
Background: Arthritis pain is primarily managed by nonsteroidal anti-inflammatory drugs (NSAIDs), such as diclofenac. Topical diclofenac gel is limited in efficacy due to its limited penetration through the skin. This study investigates the use of a multihour, wearable, localized, sonophoresis transdermal drug delivery device for the penetration en...
COVID-19 pandemic: an overview of epidemiology, pathogenesis, diagnostics and potential vaccines and therapeutics.
Published in Therapeutic delivery
At the time of writing this review, severe acute respiratory coronavirus syndrome-2 (SARS-CoV-2) has infected more than 2,355,853 patients and resulted in more than 164,656 deaths worldwide (as of 20 April 2020). This review highlights the preventive measures, available clinical therapies and the potential of vaccine development against SARS-CoV-2 ...
