Park, Dong Jin Kwon, Tae Gyun Park, Jae Young Joung, Jae Young Ha, Hong Koo Jeon, Seong Soo Hong, Sung-Hoo Park, Sungchan Lee, Seung Hwan Cho, Jin Seon
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Published in
The world journal of men's health
This study aimed to compare the short-term outcomes and safety profiles of androgen-deprivation therapy (ADT)+abiraterone/prednisone with those of ADT+docetaxel in patients with de novo metastatic hormone-sensitive prostate cancer (mHSPC). A web-based database system was established to collect prospective cohort data for patients with mHSPC in Kore...
Franco, Juan Víctor Ariel Trivisonno, Leonel Fabrizio Sgarbossa, Nadia Alvez, Gustavo Ariel Fieiras, Cecilia Escobar Liquitay, Camila Micaela Jung, Jae Hung
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The world journal of men's health
To assess the effects of Serenoa repens in the treatment of men with lower urinary tract symptoms (LUTS) consistent with benign prostatic hyperplasia (BPH). We performed a comprehensive search using multiple databases up to September 2022 with no language or publication status restrictions. We included parallel-group randomized controlled trials of...
Fu, Longlong Fang, Fang Guo, Ying Ma, Jing Wang, Shusong Gu, Yiqun Yan, Xiangming Lu, Wenhong Liu, Ying
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The world journal of men's health
This study aimed to identify the altered pathways and genes associated with freezing damage in human sperm during cryopreservation by multiomics analysis. Fifteen fresh human semen samples were collected for transcriptomic analysis, and another 5 fresh human semen samples were obtained for metabolomic analysis. For each semen sample, 1 mL was cryop...
Hu, Daoyuan Ge, Yunlong Xi, Yuhang Chen, Jialiang Wang, Hua Zhang, Chi Cui, Yubin He, Lizhao Su, Ying Chen, Jun
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Published in
The world journal of men's health
The poor retention and ambiguous differentiation of stem cells (SCs) within corpus cavernosum (CC) limit the cell application in erectile dysfunction (ED). Herein, the effects and mechanism of microRNA-145 (miR-145) gene modification on modulating the traits and fate of bone marrow-derived mesenchymal stem cells (BMSCs) were investigated. The effec...
El Ansari, Walid Arafa, Mohamed Lock, Merilyn Shah, Rupin Agarwal, Ashok
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The world journal of men's health
This is the first study to assess the impact of an online microsurgical testicular sperm extraction (mTESE) masterclass. We: 1) describe the masterclass's scientific content; 2) appraise the participants' acquisition of knowledge; 3) gauge whether the extent of improvement of the participants' knowledge/skills was influenced by demographic/professi...
Cilio, Simone Fallara, Giuseppe Lupo Stanghellini, Maria Teresa Ciceri, Fabio Montorsi, Francesco Lunghi, Francesca Salonia, Andrea
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The world journal of men's health
Hydroxyurea (HU) is a cytoreductive agent used as standard treatment option for sickle cell anaemia/disease (SCD), essential thrombocythemia (ET), and polycythaemia vera (PV). Despite its overall good safety profile, its use also in relatively young patients raises an interest on its potential impact on spermatogenesis. To perform a systematic revi...
Lee, Geum-Hwa Lee, Hwa-Young Zhao, Luo Rashid, Mohammad Mamun Ur Kim, Myung Ki Jeong, Young Beom Chae, Han-Jung Shin, Yu Seob
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The world journal of men's health
Benign prostate hyperplasia (BPH) is a common age-related chronic condition. Its pathogenesis involves androgen imbalance, inflammation, oxidative stress, and endoplasmic reticulum (ER) stress. This study aims to assess the protective effect of finasteride, a 5α-reductase inhibitor, against testosterone propionate (TP)-induced BPH in rats and explo...
Cannarella, Rossella Leanza, Claudia Crafa, Andrea Barbagallo, Federica La Vignera, Sandro Condorelli, Rosita Angela Calogero, Aldo Eugenio
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The world journal of men's health
The mesoderm specific transcription (MEST) gene is a paternally expressed imprinted gene that appears to play a role in embryo survival. The latest meta-analysis on MEST methylation pattern in spermatozoa of infertile patients found higher methylation in spermatozoa from infertile patients than fertile controls. To provide an updated and comprehens...
Hong, Jian-Hua Kuo, Ming-Chieh Cheng, Yung-Ting Lu, Yu-Chuan Huang, Chao-Yuan Liu, Shih-Ping Chow, Po-Ming Huang, Kuo-How Chueh, Shih-Chieh Jeff Chen, Chung-Hsin
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Published in
The world journal of men's health
Active surveillance (AS) is one of the management options for patients with low-risk and select intermediate-risk prostate cancer (PC). However, factors predicting disease reclassification and conversion to active treatment from a large population of pure Asian cohorts regarding AS are less evaluated. This study investigated the intermediate-term o...
Kim, Jongwon So, Byeongchan Heo, Yongki So, Hongyun Jo, Jung Ki
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The world journal of men's health
Many contraceptive methods have been developed over the years due to high demand. However, female contraceptive pills and devices do not work for all females due to health conditions and side effects. Also, the number of males who want to actively participate in family planning is gradually increasing. However, the only contraceptive options curren...