Russell, Joshua Coulter Burnaevskiy, Nikolay Ma, Bridget Mailig, Miguel Arenas Faust, Franklin Crane, Matt Kaeberlein, Matt Mendenhall, Alexander
Published in
The journals of gerontology. Series A, Biological sciences and medical sciences
The function of the pharynx, an organ in the model system Caenorhabditis elegans, has been correlated with lifespan and motility (another measure of health) since 1980. In this study, in order to further understand the relationship between organ function and lifespan, we measured the age-related decline of the pharynx using an electrophysiological ...
Morris, Rosie Lord, Sue Lawson, Rachael A Coleman, Shirley Galna, Brook Duncan, Gordon W Khoo, Tien K Yarnall, Alison J Burn, David J Rochester, Lynn
...
Published in
The journals of gerontology. Series A, Biological sciences and medical sciences
This provides novel evidence for gait as a clinical biomarker for PD cognitive decline in early disease.
Choe, Yu-Ri Joh, Ju-Youn Kim, Yeon-Pyo
Published in
The journals of gerontology. Series A, Biological sciences and medical sciences
Our proposed cut-off points for low GS and low ASM should be useful in the diagnosis of sarcopenia in older Korean people.
Alway, Stephen E McCrory, Jean L Kearcher, Kalen Vickers, Austen Frear, Benjamin Gilleland, Diana L Bonner, Daniel E Thomas, James M Donley, David A Lively, Mathew W
...
Published in
The journals of gerontology. Series A, Biological sciences and medical sciences
Older men (n = 12) and women (n = 18) 65-80 years of age completed 12 weeks of exercise and took either a placebo or resveratrol (RSV) (500 mg/d) to test the hypothesis that RSV treatment combined with exercise would increase mitochondrial density, muscle fatigue resistance, and cardiovascular function more than exercise alone. Contrary to our hypo...
Gagliardi, Cristina Corsonello, Andrea Di Rosa, Mirko Fabbietti, Paolo Cherubini, Antonio Mercante, Oriano Mazzei, Bruno Postacchini, Demetrio Deales, Alberto Bustacchini, Silvia
...
Published in
The journals of gerontology. Series A, Biological sciences and medical sciences
Patients experiencing recent pre-admission functional decline should be considered as those for which the geriatric approach may lead to the better functional result in the acute care setting. CGA allows to individuate risk factors to be addressed in the acute care setting.
Li, Danni Misialek, Jeffrey R Huang, Fangying Windham, B Gwen Yu, Fang Alonso, Alvaro
Published in
The journals of gerontology. Series A, Biological sciences and medical sciences
Plasma SM(OH)s may be independently associated with physical function in older adults.
Houston, Denise K Neiberg, Rebecca H Miller, Michael E Hill, James O Jakicic, John M Johnson, Karen C Gregg, Edward W Hubbard, Van S Pi-Sunyer, Xavier Rejeski, W Jack
...
Published in
The journals of gerontology. Series A, Biological sciences and medical sciences
An intensive lifestyle intervention has modest but significant long-term benefits on physical function in overweight and obese middle-aged and older adults with type 2 diabetes.
Shardell, Michelle Semba, Richard D Kalyani, Rita R Bandinelli, Stefania Prather, Aric A Chia, Chee W Ferrucci, Luigi
Published in
The journals of gerontology. Series A, Biological sciences and medical sciences
Higher plasma klotho concentrations were associated with lower likelihoods of frailty and particularly exhaustion. Future studies should investigate modifiable mechanisms through which klotho may affect the frailty syndrome.
Kageyama, Shinya Takeshita, Toru Furuta, Michiko Tomioka, Mikiko Asakawa, Mikari Suma, Shino Takeuchi, Kenji Shibata, Yukie Iwasa, Yasuyuki Yamashita, Yoshihisa
...
Published in
The journals of gerontology. Series A, Biological sciences and medical sciences
The tongue microbiota type was significantly associated with an increased mortality risk from pneumonia in nursing home residents.
Maffei, Vincent J Kim, Sangkyu Blanchard, Eugene 4th Luo, Meng Jazwinski, S Michal Taylor, Christopher M Welsh, David A
Published in
The journals of gerontology. Series A, Biological sciences and medical sciences
The human gastrointestinal microbiota plays a key homeostatic role in normal functioning of physiologic processes commonly undermined by aging. We used a previously validated 34-item frailty index (FI34) to identify changes in gut microbiota community structure associated with biological age of community-dwelling adults. Stool 16S rRNA cDNA librari...
