Xiong, Zichao Wu, Jiamin Sun, Yao Bai, Mei Niu, Fanglin Jin, Tianbo
Published in
The journal of gene medicine
The present study investigated whether 16 single nucleotide polymorphisms (SNPs), selected based on minor allele frequencies, Hardy-Weinberg equilibrium and reported SNPs related to the susceptibility of certain gastrointestinal cancer, were associated with esophageal cancer (EC) risk in a Chinese Han population. We genotyped 16 SNPs among 506 case...
Lu, Hui Zhang, Qian Sun, Yaqiong Wu, Dedong Liu, Liying
Published in
The journal of gene medicine
LINC00689 acts one critical regulatory role in several tumors. However, the functional, regulatory mechanism and expression of LINC00689 remains unknown in gastric cancer. LINC00689 and miR-338-3p levels were determined using a quantitative reverse transcriptase-polymerase chain reaction analysis and an enzyme-linked immunoassay and a cell-counting...
Shahabipour, Fahimeh Oskuee, Reza Kazemi Shokrgozar, Mohammad Ali Naderi-Meshkin, Hojjat Goshayeshi, Lena Bonakdar, Shahin
Published in
The journal of gene medicine
Dentin matrix protein 1 (DMP1) is highly expressed in mineralized tooth and bone, playing a critical role in mineralization and phosphate metabolism. One important role for the expression of DMP1 in the nucleus of preosteoblasts is the up-regulation of osteoblast-specific genes such as osteocalcin and alkaline phosphatase1 . The present study aimed...
Zhang, Zhongzhao Jia, Min Wen, Changhui He, Aijuan Ma, Zunfeng
Published in
The journal of gene medicine
Long non-coding RNAs (lncRNAs) play important roles in the progression of tumors. However, the function and expression of SCARNA2 in cutaneous squamous cell carcinoma (cSCC) is still unreported. A quantitative polymerase chain reaction was applied to study the expression of SCARNA2 and miR-342-3p. Cell counting kit-8, flow cytometry and transwell a...
Zhu, Juan Wei, Yunjian Wang, Zhen Jie, Qiuling Sun, Fei Li, Qi Long, Ping Huang, Yuanhua Yu, Yanhong Ma, Yanlin
...
Published in
The journal of gene medicine
Pre-eclampsia (PE) is a major cause of maternal and neonatal mortality and morbidity. Abnormal invasion of trophoblast cells is a major pathogenesis observed in PE. In the present study, we aimed to explore the association between forkhead box A1 (FOXA1) and early-onset pre-eclampsia (EOPE) and to determine the effects of FOXA1 on trophoblast cell ...
Mohamadian, Malihe Naseri, Mohsen Ghandil, Pegah Bahrami, Afsane Momen, Ali Akbar
Published in
The journal of gene medicine
Congenital muscular dystrophy (CMD) refers to hypotonia and delayed motor development that is manifested at or near the birth. Additional presentations have been observed in CMD syndromes. Thorough clinical examinations were performed on two unrelated Iranian families with typical symptoms of CMD and uncommon features such as intellectual disabilit...
Wang, Weisheng Liu, Zhiming Zhang, Xuegang Liu, Junning Gui, Junqing Cui, Maorong Li, Yong
Published in
The journal of gene medicine
The micro RNA (miRNA)/histone deacetylase 9 (HDAC9) signaling axis has been reported to be involved in initiating and developing multiple malignant tumors. In the present study, we aimed to determine whether miR-211-5p serves as a post-transcriptional regulator in bladder cancer (BCa) cell proliferation and apoptosis by targeting HDAC9. miRNA expre...
Rahim, Fakher Abbasi Pashaki, Pejman Jafarisani, Moslem Ghorbani, Fatemeh Ebrahimi, Ammar
Published in
The journal of gene medicine
For cartilage regeneration, stem cells are a promising cell source; however, even the advances made in the differentiation of stem cells into precursor-differentiated cartilage cells have not been successful with respect to reprograming these cells to achieve complete differentiation and fully functioning cells until now. Previous findings suggest ...
Kempiński, Karol Romantowski, Jan Maciejewska, Agnieszka Pawłowski, Ryszard Chełmińska, Marta Jassem, Ewa Niedoszytko, Marek
Published in
The journal of gene medicine
Hymenoptera venom allergy (HVA) is of great concern because of the possibility of anaphylaxis, which may be fatal. Venom immunotherapy (VIT) is the only disease-modifying treatment in HVA and, although efficient, its mechanism remains partially unknown. Gene expression analysis may be helpful for establishing a proper model of tolerance induction d...
Sun, Farui Yu, Ziliang Wu, Bingbing Zhang, Haiping Ruan, Jing
Published in
The journal of gene medicine
Numerous studies have shown that aberrant expression of long non-coding RNAs (lncRNAs) is associated with the development and metastasis of osteosarcoma (OS). However, the role and function of LINC00319 with respect to regulating OS progression is unknown. The present study aimed to reveal the function and related mechanism of LINC00319 in OS. The ...
