Tay, Tunn Ren van Boven, Job F M Chan, Amy Hew, Mark
Published in
The journal of allergy and clinical immunology. In practice
Inhaled therapy is the cornerstone of chronic airway disease therapy, but poor adherence to controller inhalers worsens clinical outcomes and increases cost. Monitoring of controller use is needed to improve adherence, and monitoring of reliever use can predict impending exacerbations. Both can be accurately achieved by electronic inhaler monitorin...
Li, Lily Bensko, Jillian Buchheit, Kathleen Saff, Rebecca R Laidlaw, Tanya M
Published in
The journal of allergy and clinical immunology. In practice
Nonsteroidal anti-inflammatory drug (NSAID) outpatient challenge protocols are not standardized. They vary in clinical practice and can be time- and resource-intensive to perform. To investigate the safety and outcomes of two-step outpatient NSAID challenges to evaluate patients with non-aspirin-exacerbated respiratory disease (AERD)-related NSAID ...
Arnold, Donald H Gong, Wu Antoon, James W Bacharier, Leonard B Stewart, Thomas G Johnson, David P Akers, Wendell S Hartert, Tina V
Published in
The journal of allergy and clinical immunology. In practice
There is limited knowledge regarding whether intravenous magnesium (IV-Mg) improves outcomes in children with acute asthma exacerbations. To examine whether IV-Mg improves outcomes in children with moderate and severe exacerbations. We performed a secondary analysis using data from a prospective observational cohort of children aged 5 to 17 years w...
Gater, Adam Nelsen, Linda Coon, Cheryl D Eremenco, Sonya O'Quinn, Sean Khan, Asif H Eckert, Laurent Staunton, Hannah Bonner, Nicola Hall, Rebecca
...
Published in
The journal of allergy and clinical immunology. In practice
The Asthma Daytime Symptom Diary (ADSD) and the Asthma Nighttime Symptom Diary (ANSD) were developed to meet the need for standardized patient-reported measures of asthma symptoms to assess treatment trial outcomes in adults and adolescents. To determine scoring and evaluate the measurement properties of the ADSD/ANSD. Adolescents (12-17 years) and...
Mullol, Joaquim Bachert, Claus Amin, Nikhil Desrosiers, Martin Hellings, Peter W Han, Joseph K Jankowski, Roger Vodicka, Jan Gevaert, Philippe Daizadeh, Nadia
...
Published in
The journal of allergy and clinical immunology. In practice
Loss of smell (LoS) is one of the most troublesome and difficult-to-treat symptoms of severe chronic rhinosinusitis with nasal polyps (CRSwNP). To assess the impact of dupilumab on sense of smell in severe CRSwNP. In the randomized SINUS-24 and SINUS-52 studies, adults with severe CRSwNP received dupilumab 300 mg subcutaneously or matching placebo ...
Ardura-Garcia, Cristina Pedersen, Eva S L Mallet, Maria Christina de Jong, Carmen C M Barben, Juerg Jochmann, Anja Jung, Andreas Mueller-Suter, Dominik Regamey, Nicolas Singer, Florian
...
Published in
The journal of allergy and clinical immunology. In practice
Asthma treatment should be modified according to symptom control and future risk, but there are scarce data on what drives treatment adjustments in routine tertiary care. We studied factors that drive asthma treatment adjustment in pediatric outpatient clinics. We performed a cross-sectional analysis of the Swiss Paediatric Airway Cohort, a clinica...
Rodríguez, Erin M Pollack, Craig Evan Keet, Corinne Peng, Roger D Balcer-Whaley, Susan Custer, James Cimbolic, Pete Matsui, Elizabeth C
Published in
The journal of allergy and clinical immunology. In practice
Neighborhood and caregiver characteristics have each been linked to children's asthma outcomes, but less is known about how caregiver psychosocial functioning may explain the link between neighborhood characteristics and asthma outcomes. To examine associations between neighborhood safety, caregiver stress and depressive symptoms, and children's as...
Grunwell, Jocelyn R Opolka, Cydney Mason, Carrie Fitzpatrick, Anne M
Published in
The journal of allergy and clinical immunology. In practice
Social determinants of health are associated with asthma prevalence and healthcare use in children with asthma, but are multifactorial and complex. Whether social determinants similarly influence exacerbation severity is not clear. Composite measures of social determinants of health and readmission outcomes were evaluated in a large regional cohort...
Sagheb, Elham Wi, Chung-Il Yoon, Jungwon Seol, Hee Yun Shrestha, Pragya Ryu, Euijung Park, Miguel Yawn, Barbara Liu, Hongfang Homme, Jason
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Published in
The journal of allergy and clinical immunology. In practice
Clinicians' asthma guideline adherence in asthma care is suboptimal. The effort to improve adherence can be enhanced by assessing and monitoring clinicians' adherence to guidelines reflected in electronic health records (EHRs), which require costly manual chart review because many care elements cannot be identified by structured data. This study wa...
Bartosik, Tina Jensen, Sebastian A Afify, Sheriene M Bianchini, Rodolfo Hufnagl, Karin Hofstetter, Gerlinde Berger, Markus Bastl, Maximilian Berger, Uwe Rivelles, Elisa
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Published in
The journal of allergy and clinical immunology. In practice
Functional iron deficiency facilitates allergy development and amplifies the symptom burden in people experiencing allergies. Previously we selectively delivered micronutrients to immune cells with β-lactoglobulin as carrier (holoBLG), resulting in immune resilience and allergy prevention. The clinical efficacy of a food for special medical purpose...
