The War-Zone Mentality - Mental Health Effects of Gun Violence in U.S. Children and Adolescents.
Published in The New England journal of medicine
A Hidden Crisis.
Published in The New England journal of medicine
Product Hopping in the Drug Industry - Lessons from Albuterol.
Published in The New England journal of medicine
Autosomal Dominant Osteopetrosis.
Published in The New England journal of medicine
Routine Functional Testing or Standard Care in High-Risk Patients after PCI.
...Published in The New England journal of medicine
There are limited data from randomized trials to guide a specific follow-up surveillance approach after myocardial revascularization. Whether a follow-up strategy that includes routine functional testing improves clinical outcomes among high-risk patients who have undergone percutaneous coronary intervention (PCI) is uncertain. We randomly assigned...
Open-Source Automated Insulin Delivery in Type 1 Diabetes.
...Published in The New England journal of medicine
Open-source automated insulin delivery (AID) systems are used by many patients with type 1 diabetes. Data are needed on the efficacy and safety of an open-source AID system. In this multicenter, open-label, randomized, controlled trial, we assigned patients with type 1 diabetes in a 1:1 ratio to use an open-source AID system or a sensor-augmented i...
Clinical Spectrum of Children with Acute Hepatitis of Unknown Cause.
...Published in The New England journal of medicine
Since January 2022, there has been an increase in reports of cases of acute hepatitis of unknown cause in children. Although cases have been reported across multiple continents, most have been reported in the United Kingdom. Investigations are ongoing to identify the causative agent or agents. We conducted a retrospective study involving children r...
A Case Series of Children with Acute Hepatitis and Human Adenovirus Infection.
...Published in The New England journal of medicine
Human adenoviruses typically cause self-limited respiratory, gastrointestinal, and conjunctival infections in healthy children. In late 2021 and early 2022, several previously healthy children were identified with acute hepatitis and human adenovirus viremia. We used International Classification of Diseases, 10th Revision, codes to identify all chi...
Once-Weekly Dulaglutide for the Treatment of Youths with Type 2 Diabetes.
...Published in The New England journal of medicine
The incidence of type 2 diabetes mellitus is increasing among youths. Once-weekly treatment with dulaglutide, a glucagon-like peptide-1 receptor agonist, may have efficacy with regard to glycemic control in youths with type 2 diabetes. In a double-blind, placebo-controlled, 26-week trial, we randomly assigned participants (10 to 85th percentile) be...
Tirzepatide Once Weekly for the Treatment of Obesity.
...Published in The New England journal of medicine
Obesity is a chronic disease that results in substantial global morbidity and mortality. The efficacy and safety of tirzepatide, a novel glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist, in people with obesity are not known. In this phase 3 double-blind, randomized, controlled trial, we assigned 2539 adults ...
