Published in Clinical reviews in allergy & immunology
Cryoglobulins are immunoglobulins that reversibly precipitate in the cold. They come in different flavours and, as such, are differentially associated with lymphoproliferative diseases (type I), or systemic autoimmune diseases, and/or infectious diseases (type II/III). The clinical manifestations of cryoglobulinaemia result from either hyper-viscos...
Published in Lancet (London, England)
US Food and Drug Administration.
Published in Lancet (London, England)
Published in Lancet (London, England)
Published in Lancet (London, England)
Myelodysplastic syndromes are clonal marrow stem-cell disorders, characterised by ineffective haemopoiesis leading to blood cytopenias, and by progression to acute myeloid leukaemia in a third of patients. 15% of cases occur after chemotherapy or radiotherapy for a previous cancer; the syndromes are most common in elderly people. The pathophysiolog...
Published in Circulation
Published in Circulation
Published in Lancet (London, England)
Adrenal insufficiency is the clinical manifestation of deficient production or action of glucocorticoids, with or without deficiency also in mineralocorticoids and adrenal androgens. It is a life-threatening disorder that can result from primary adrenal failure or secondary adrenal disease due to impairment of the hypothalamic-pituitary axis. Promp...
Published in Lancet (London, England)
Cancer Research UK, British Heart Foundation, UK Medical Research Council.
Published in Lancet (London, England)
