Durability of antiviral therapy for chronic hepatitis C after achieving sustained virological response.
Published in The Korean journal of hepatology
Clinical features and treatment efficacy of peginterferon alfa plus ribavirin in chronic hepatitis C patients coinfected...
...Published in The Korean journal of hepatology
Cross-sectional studies have documented that 2-10% of patients who are chronically infected with hepatitis C virus (HCV) are also positive for hepatitis B virus (HBV) surface antigen (HBsAg). Data related to HCV-HBV coinfection are lacking in Korea. This study evaluated the clinical characteristics, the treatment efficacy of peginterferon alfa plus...
A case of leukemoid reaction in a patient with sarcomatous hepatocellular carcinoma.
Published in The Korean journal of hepatology
A leukemoid reaction is defined as reactive leukocytosis exceeding 50,000/mm(3), with a significant increase in early neutrophil precursors, and can be a paraneoplastic manifestation of various malignant tumors. A 71-year-old male patient complained of decreased appetite, fatigue, and abdominal fullness. He had a palpable, firm liver, and laborator...
Peginterferon alpha and ribavirin combination therapy in patients with hepatitis C virus-related liver cirrhosis.
Published in The Korean journal of hepatology
Pegylated interferon (peginterferon) and ribavirin combination therapy is less effective and associated with a higher frequency of serious complications in chronic hepatitis C patients with cirrhosis than in noncirrhotic patients. This study evaluated the efficacy and tolerability of peginterferon and ribavirin treatment in patients with hepatitis ...
Effect of aldosterone on the amplification of oncolytic vaccinia virus in human cancer lines.
...Published in The Korean journal of hepatology
JX-594 is an oncolytic virus derived from the Wyeth vaccinia strain that causes replication-dependent cytolysis and antitumor immunity. Starting with a cross-examination of clinical-trial samples from advanced hepatocellular carcinoma patients having high levels of aldosterone and virus amplification in JX-594 treatment, we investigated the associa...
Durability of a sustained virological response in chronic hepatitis C patients treated with pegylated interferon alfa an...
...Published in The Korean journal of hepatology
The reappearance rates of hepatitis C virus (HCV) RNA after a sustained virological response (SVR) have been reported to be 1-2%. We investigated the reappearance rate of HCV RNA after SVR in chronic hepatitis C (CHC) patients treated with pegylated interferon (PEG-IFN) and ribavirin. In total, 292 CHC patients who achieved an SVR after PEG-IFN and...
The diagnosis and treatment of primary biliary cirrhosis.
Published in The Korean journal of hepatology
Primary biliary cirrhosis (PBC) is a slowly progressive cholestatic liver disease of autoimmune etiology. The initial presentation of PBC is various from asymptomatic, abnormal liver biochemical tests to overt cirrhosis. The diagnosis of PBC is based on cholestatic biochemical liver tests, presence of antimitochondrial antibody and histologic findi...
Apoptosis and diagnosis of nonalcoholic steatohepatitis.
Published in The Korean journal of hepatology
Clinical significance of occult hepatitis B virus infection in chronic hepatitis C patients.
...Published in The Korean journal of hepatology
We investigated the frequency of occult hepatitis B virus (HBV) infection in anti-hepatitis C virus (HCV)-positive individuals and the effects of occult HBV infection on the severity of liver disease. Seventy-one hepatitis B virus surface-antigen (HBsAg)-negative patients were divided according to their HBV serological status into groups A (anti-HB...
Early hepatocellular carcinoma.
Published in The Korean journal of hepatology
