Published in The Journal of rheumatology
Undoubtedly, individuals with systemic lupus erythematosus (SLE) are at higher risk for developing cerebrovascular disease than counterparts from the general population without SLE. In a metaanalysis of studies from around the world, the likelihood of individuals with SLE developing both ischemic and hemorrhagic stroke (intracerebral and/or subarac...
Published in The Journal of rheumatology
For his Second Labor, Heracles was tasked with slaying the Hydra, a serpentine monster from ancient Greek mythology who possessed many heads. When Heracles attempted to decapitate the monster, two new heads grew in place of each severed head, an expression of hopelessness of such struggle for anyone but the hero. The invulnerability of the Hydra wa...
Published in The Journal of rheumatology
SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome is a rare chronic inflammatory disease involving bone, joints, and skin1 No consensus has been reached on the treatment of SAPHO syndrome and the current options may lead to variable outcomes2.
Published in The Journal of rheumatology
To test the addition of pain and fatigue to the Composite Psoriatic Arthritis Disease Activity (CPDAI) and the Group for Research and Assessment of Psoriasis and PsA (GRAPPA) Composite Exercise (GRACE) composite measures of psoriatic arthritis (PsA). Clinical and patient-reported outcome measures were assessed in patients with PsA at 3 consecutive ...
Published in The Journal of rheumatology
The evaluation of the evolution of telomere length from peripheral blood leukocytes (PBL) in subjects from the Osteoarthritis Initiative (OAI) cohort in relation to the incidence of osteoarthritis (OA) and explore its possible interactive influence with the mitochondrial DNA (mtDNA) haplogroup. Dynamics of telomere sequence loss was quantified in P...
Published in The Journal of rheumatology
Major salivary gland ultrasonography (SGUS) is widely used to diagnose primary Sjögren syndrome (pSS) in a large majority of individuals as well as in specific situations, such as when lymphoma is suspected1,2,3 It is a powerful and noninvasive procedure that provides a global image of the parenchymal lesions of the major salivary gland and clearly...
Published in The Journal of rheumatology
To test shortened versions of the psoriatic arthritis (PsA) composite measures for use in routine clinical practice. Clinical and patient-reported outcome measures (PROMs) were assessed in patients with PsA at 3 consecutive follow-up visits in a UK multicenter observational study. Shortened versions of the Composite Psoriatic Arthritis Disease Acti...
Published in The Journal of rheumatology
From the first description in 1972 as "subacute and chronic recurrent osteomyelitis" to the currently recognized chronic recurrent multifocal osteomyelitis (CRMO) or chronic nonbacterial osteitis (CNO), diagnosis and monitoring of patients with this disease has been and continues to be a challenge1,2 While the most common presenting symptom is foca...
Published in The Journal of rheumatology
This article summarizes sessions that dealt with axial psoriatic arthritis (axPsA) at the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) 2020 virtual meeting. The summary includes the symposium, which comprised a plenary presentation by Dr. Dafna Gladman from Toronto, Canada, as well as a panel discussion with Dr. P...
Published in The Journal of rheumatology
In Rheumatoid Arthritis (RA), evidence regarding the effectiveness of a second biologic Disease Modifying Anti-Rheumatic Drugs (bDMARDs) in patients whose first ever bDMARD was a non-tumor-necrosis-factor-inhibitor (TNFi) bDMARD is limited. The objective of this study was therefore to assess the outcome of the second bDMARD (non-TNFi [rituximab, ab...
