Granger, Steven J Glynn, Laura M Sandman, Curt A Small, Steven L Obenaus, Andre Keator, David B Baram, Tallie Z Stern, Hal Yassa, Michael A Davis, Elysia Poggi
...
Published in
The Journal of neuroscience : the official journal of the Society for Neuroscience
Across species, unpredictable patterns of maternal behavior are emerging as novel predictors of aberrant cognitive and emotional outcomes later in life. In animal models, exposure to unpredictable patterns of maternal behavior alters brain circuit maturation and cognitive and emotional outcomes. However, whether exposure to such signals in humans a...
Cox, Christopher R Rogers, Timothy T
Published in
The Journal of neuroscience : the official journal of the Society for Neuroscience
The human cortex encodes information in complex networks that can be anatomically dispersed and variable in their microstructure across individuals. Using simulations with neural network models, we show that contemporary statistical methods for functional brain imaging-including univariate contrast, searchlight multivariate pattern classification, ...
Salvan, Piergiorgio Wassenaar, Thomas Wheatley, Catherine Beale, Nicholas Cottaar, Michiel Papp, Daniel Bastiani, Matteo Fitzgibbon, Sean Duff, Euguene Andersson, Jesper
...
Published in
The Journal of neuroscience : the official journal of the Society for Neuroscience
The World Health Organization promotes physical exercise and a healthy lifestyle as means to improve youth development. However, relationships between physical lifestyle and human brain development are not fully understood. Here, we asked whether a human brain-physical latent mode of covariation underpins the relationship between physical activity,...
Donato, Flavio Alberini, Cristina M Amso, Dima Dragoi, George Dranovsky, Alex Newcombe, Nora S
Published in
The Journal of neuroscience : the official journal of the Society for Neuroscience
The formation of memories that contain information about the specific time and place of acquisition, which are commonly referred to as "autobiographical" or "episodic" memories, critically relies on the hippocampus and on a series of interconnected structures located in the medial temporal lobe of the mammalian brain. The observation that adults re...
Liu, Jun Lin, Longnian Wang, Dong V
Published in
The Journal of neuroscience : the official journal of the Society for Neuroscience
Fear of heights is evolutionarily important for survival, yet it is unclear how and which brain regions process such height threats. Given the importance of the basolateral amygdala (BLA) in mediating both learned and innate fear, we investigated how BLA neurons may respond to high-place exposure in freely behaving male mice. We found that a discre...
Balasubramaniam, Ramesh Haegens, Saskia Jazayeri, Mehrdad Merchant, Hugo Sternad, Dagmar Song, Joo-Hyun
Published in
The Journal of neuroscience : the official journal of the Society for Neuroscience
The ability to perceive and produce movements in the real world with precise timing is critical for survival in animals, including humans. However, research on sensorimotor timing has rarely considered the tight interrelation between perception, action, and cognition. In this review, we present new evidence from behavioral, computational, and neura...
Geng, Fengji Botdorf, Morgan Riggins, Tracy
Published in
The Journal of neuroscience : the official journal of the Society for Neuroscience
Source memory improves substantially during childhood. This improvement is thought to be closely related to hippocampal maturation. As previous studies have mainly used cross-sectional designs to assess relations between source memory and hippocampal function, it remains unknown whether changes in the brain precede improvements in memory or vice ve...
Rose, Timothy R Marron Fernandez de Velasco, Ezequiel Vo, Baovi N Tipps, Megan E Wickman, Kevin
Published in
The Journal of neuroscience : the official journal of the Society for Neuroscience
Drug-induced neuroadaptations in the mPFC have been implicated in addictive behaviors. Repeated cocaine exposure has been shown to increase pyramidal neuron excitability in the prelimbic (PL) region of the mouse mPFC, an adaptation attributable to a suppression of G protein-gated inwardly rectifying K+ (GIRK) channel activity. After establishing th...
Lipovsek, Marcela Bardy, Cedric Cadwell, Cathryn R Hadley, Kristen Kobak, Dmitry Tripathy, Shreejoy J
Published in
The Journal of neuroscience : the official journal of the Society for Neuroscience
Single-cell transcriptomic approaches are revolutionizing neuroscience. Integrating this wealth of data with morphology and physiology, for the comprehensive study of neuronal biology, requires multiplexing gene expression data with complementary techniques. To meet this need, multiple groups in parallel have developed "Patch-seq," a modification o...
Hanganu-Opatz, Ileana L Butt, Simon J B Hippenmeyer, Simon De Marco García, Natalia V Cardin, Jessica A Voytek, Bradley Muotri, Alysson R
Published in
The Journal of neuroscience : the official journal of the Society for Neuroscience
The sensory and cognitive abilities of the mammalian neocortex are underpinned by intricate columnar and laminar circuits formed from an array of diverse neuronal populations. One approach to determining how interactions between these circuit components give rise to complex behavior is to investigate the rules by which cortical circuits are formed ...
