Sullivan, Patrick W Lanz, Miguel J Ghushchyan, Vahram H Kavati, Abhishek LeCocq, Jason Ortiz, Benjamin Maselli, Diego J
Published in
The Journal of asthma : official journal of the Association for the Care of Asthma
Objective: To compare healthcare resource utilization (HCRU), healthcare expenditures, and work productivity and activity impairment within a general asthma population with persistent asthma and evidence of allergy (PA-EA) and persistent asthma with no evidence of allergy (PA-NEA).Methods: We conducted a retrospective analysis of survey responses a...
Lin, Ada T Moore-Clingenpeel, Melissa Karsies, Todd J
Published in
The Journal of asthma : official journal of the Association for the Care of Asthma
Objectives: Continuous nebulized albuterol is frequently used to treat children with status asthmaticus in the pediatric intensive care unit (PICU) but can have cardiovascular side effects. Limited data exist comparing different dosages. The purpose of this study was to compare hemodynamic side effects of two continuous albuterol doses (10 vs. 25 m...
Asano, Takamitsu Kanemitsu, Yoshihiro Takemura, Masaya Fukumitsu, Kensuke Kurokawa, Ryota Inoue, Yoshitsugu Takeda, Norihisa Yap, Jennifer Maries G Ito, Keima Kitamura, Yuki
...
Published in
The Journal of asthma : official journal of the Association for the Care of Asthma
Background: Asthma is characterized by airway inflammation, variable airflow obstruction, and airway hyperresponsiveness (AHR). Generally, AHR takes longer to resolve than does airflow obstruction or clinical symptoms. AHR occasionally persists despite adequate asthma treatment.Objective: To evaluate factors which associates with residual AHR in pa...
Rodriguez-Martinez, Carlos E Sossa-Briceño, Monica P Castro-Rodriguez, Jose A
Published in
The Journal of asthma : official journal of the Association for the Care of Asthma
Objective: Although the efficacy of systemic corticosteroids (SCs) in acute asthma exacerbations is well established, the fact that many children still require admission to hospital and that SCs have a slow onset of action are cause of concern. For this reason, the use of inhaled corticosteroids (ICS) as a therapy added to SCs has been explored, wi...
Bernstein, David Pavord, Ian D Chapman, Kenneth R Follows, Richard Bentley, Jane H Pouliquen, Isabelle Bradford, Eric
Published in
The Journal of asthma : official journal of the Association for the Care of Asthma
Objective: To evaluate usability of mepolizumab as a liquid drug product self-administered via a single-use prefilled autoinjector (AI) by patients with severe eosinophilic asthma (SEA), or their caregivers, in-clinic and at home.Methods: This open-label, single-arm, Phase IIIa study (NCT03099096; GSK ID: 204959) included patients aged ≥12 years wi...
Heru Setiawan, Christianus Widayati, Aris Virginia, Dita Maria Armour, Carol Saini, Bandana
Published in
The Journal of asthma : official journal of the Association for the Care of Asthma
Introduction: Community pharmacists are one of the most frequently accessed health professionals who can be involved in the provision of ongoing asthma management within the primary care setting. The aim of this study was to identify patients' views regarding current asthma care provided by their pharmacists and their perspectives on future pharmac...
Kalra, Saminder Singh Lamia, Ibrahim
Published in
The Journal of asthma : official journal of the Association for the Care of Asthma
Introduction: Azathioprine is an immune-modulating agent used in the management of autoimmune diseases and in preventing graft rejection. Its role in the management of refractory asthma is not very well-established.Case study: A 47-year-old female with an underlying severe refractory asthma, managed with high dose steroids, was seen as an outpatien...
Nelsen, Linda M Cockle, Sarah M Gunsoy, Necdet B Jones, Paul Albers, Frank C Bradford, Eric S Mullerova, Hana
Published in
The Journal of asthma : official journal of the Association for the Care of Asthma
Objective: To assess the effect of asthma exacerbations and mepolizumab treatment on health status of patients with severe asthma using the St George's Respiratory Questionnaire (SGRQ).Methods: Post hoc analyses were conducted using data from two randomized controlled trials in patients ≥12 years old with severe eosinophilic asthma randomized to re...
Roach, David J Ruangnapa, Kanokpan Fleck, Robert J Rattan, Mantosh S Zhang, Yin Hossain, Md Monir Guilbert, Theresa W Woods, Jason C
Published in
The Journal of asthma : official journal of the Association for the Care of Asthma
Objective: Image scoring systems have been developed to assess the severity of specific lung abnormalities in patients diagnosed with various pulmonary diseases except for asthma. A comprehensive asthma imaging scoring system may identify specific abnormalities potentially linking these to inflammatory phenotypes.Methods: Computed tomography (CT) i...
Cotter, Jillian M Tyler, Amy Reese, Jennifer Ziniel, Sonja Federico, Monica J Anderson Iii, William C Kupfer, Oren Szefler, Stanley J Kerby, Gwendolyn Hoch, Heather E
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Published in
The Journal of asthma : official journal of the Association for the Care of Asthma
Objective: Our hospital's pediatric Emergency Department (ED) began using dexamethasone for treating asthma exacerbations after ED studies showed non-inferiority of dexamethasone compared to prednisone. However, providers have not reached consensus on optimal inpatient steroid regimen. This study evaluates provider preference for inpatient steroid ...
