Cui, Wei-Hua Zhang, Hai-Hong Qu, Zi-Mei Wang, Zhao Zhang, De-Jin Wang, Shu
Published in
The International journal of neuroscience
The cerebral ischemia-reperfusion (I/R) model is crucial for the study of cerebral stroke. Chrysophanol (Chry) can protect nerve damage of mice in cerebral ischemia-reperfusion injury. This study aimed at investigating the neuroprotective effects of chrysophanol through mitochondrial autophagy in mice with ischemia-reperfusion injury. Adult mice we...
Wang, Fei Lin, Li Hu, Jing Zhang, Jianfang Wang, Kang
Published in
The International journal of neuroscience
Sialidosis is a rare autosomal recessive hereditary disease caused by NEU1 gene mutations. A 25-year-old woman developed generalized tonic-clonic seizures since teenage, followed by progressive visional decline and limb myoclonus. Her sister had similar presentations. Both patients were products of a consanguineous marriage. Electroencephalography ...
Rustagi, Tarush Schwab, Joseph H Iwenofu, Hans Mendel, Ehud
Published in
The International journal of neuroscience
Narrative review. To provide a narrative review for diagnosis and management of Primary spine tumors. A detailed review of literature was done to identify relevant and well cited manuscripts to construct this narrative review. Primary tumors of the spine are rare with some racial differences reported. There are numerous adjuvant technologies and de...
Calderón Guzmán, David Osnaya Brizuela, Norma Ortiz Herrera, Maribel Juárez Olguín, Hugo Veloz Corona, Quetzalli Sanchez Reyes, Lulu Valenzuela Peraza, Armando Barragán Mejía, Gerardo
Published in
The International journal of neuroscience
The purpose was to measure the effect of Oseltamivir on oxidative biomarkers and dopaminergic and serotonergic systems in brain of rats with induced hypotriglyceridemia by Bezafibrate.Male young Wistar rats were treated as follows: group 1, NaCl 0.9%, (Controls); group 2, Oseltamivir (100 mg/kg); group 3, single dose of Bezafibrate (150 mg/kg); gro...
Yang, Fan Wang, Juan Yang, Ze Ren, Zhaorui Zeng, Fanyi
Published in
The International journal of neuroscience
Pantothenate kinase associated neurodegeneration (PKAN) is a severe autosomal recessive rare disease and characterized by iron accumulation in the basal ganglia. To investigate the pathogenesis of this disease in two sibling patients with PANK in a Chinese family, whole-exome variant detection and functional analysis were performed. Clinical and ra...
Surmeli, Reyhan Surmeli, Mehmet Yalcin, Ayse Destina Yilmaz, Ayse Asli Sahin Kucuk, Ferhat
Published in
The International journal of neuroscience
Pseudo-vestibular neuritis is a clinical diagnosis for patients presenting with acute vestibular syndrome due to a central pathology. We reported a case of multiple sclerosis characterized by pseudo-vestibular neuritis. Our case was a 32-year-old male patient. The patient, who was diagnosed with multiple sclerosis in September 2019, came to the eme...
Pourahmadiyan, Azam Alipour, Paria Golchin, Neda Tabatabaiefar, Mohammad Amin
Published in
The International journal of neuroscience
Ataxia telangiectasia (A-T) is a rare autosomal recessive, multisystemic disease. Patients with the A-T syndrome present a broad spectrum of disease phenotypes. The ATM (ataxia telangiectasia mutated) gene, the only causative gene for A-T. A patient of Persian origin presenting with typical A-T was referred to our genetics centre for specialized ge...
Anagnostouli, Maria Vakrakou, Aigli G Zambelis, Thomas Boufidou, Fotini Nikolaou, Chrysoula Karandreas, Nikolaos Kilidireas, Constantinos
Published in
The International journal of neuroscience
The comorbidity of myasthenia gravis (MG), with other autoimmune disorders like systemic lupus erythematosus (SLE), is relatively frequent but the co-occurrence with chronic inflammatory demyelinating polyneuropathy (CIDP) along with various autoimmune manifestations in the absence of thymoma is of extreme rarity. Our aim is to report a case of a w...
Heidari Nia, Milad Sargazi, Saman Saravani, Ramin Mirinejad, Shekoufeh Jahantigh, Danial Shakiba, Mansoor
Published in
The International journal of neuroscience
Converging evidence has recently established the significance of γ-aminobutyric acid neurotransmitter (GABA) system in the development of schizophrenia (SCZ). We aimed to determine the association of two markers of the GABAA receptor β2 subunit gene (GABRB2), rs12187676 G/C and rs1816072 T/C, with the risk of SCZ in Iranian population. In this case...
Borikar, Sachin P Dongare, Shruti I Danao, Kishor R
Published in
The International journal of neuroscience
Learning and memory functions in animals were evaluated by using Novel object recognition (NOR) and Morris water maze (MWM) tests. Following 7 days of LPS administration, animals were subjected to NOR test on Day-8 and MWM test on Days-9 to 13 for the assessment of recognition and spatial learning and memory, respectively. LPS administration produc...
