Feng, Chong Tang, Nailong Huang, He Zhang, Guiyun Qi, Xiangqian Shi, Fei
Published in
The International journal of neuroscience
Decreased 25-hydroxyvitamin D [25(OH)D] has been reported to be related to increased risk of cerebrovascular disease. We aimed to investigate whether an association exists between 25(OH)D levels and cerebral small vessel disease (cSVD). Patients with first-ever minor ischemic stroke or transient ischemic attack were recruited prospectively during J...
Fan, Yuan Chen, Yan Zhang, Se Huang, Mengbing Wang, Shengdong Li, Ye Bai, Jie
Published in
The International journal of neuroscience
Parkinson's disease (PD) is a neurodegenerative disorder. It is caused by the degeneration of dopaminergic neurons and the dopamine (DA) deletion in the substantia nigra pars compacta (SNpc). Morphine elevates the level of dopamine in the mesolimbic dopamine system and plays a role in alleviating PD symptoms. However, the molecular mechanism is sti...
Han, Yunfeng Yang, Hongyan Li, Libo Du, Xiaohui Sun, Chao
Published in
The International journal of neuroscience
Schisanhenol is a compound derived from the fruit of a traditional Chinese herb Schisandra rubriflora. The aim of the present study was to evaluate the effect of Schisanhenol on the cognitive impairment induced by scopolamine. Male mice were randomly divided into three Schisanhenol groups (10, 30, 100 mg/kg), Galantamine group (3 mg/kg), model grou...
Al-Husseini, Muneer J Saad, Anas M El-Shewy, Kholoud M Nissan, Ninos E Gad, Mohamed M Alzuabi, Muayad A Alfaar, Ahmad Samir
Published in
The International journal of neuroscience
Glioblastoma multiforme (GBM) patients with a prior malignancy are usually excluded from clinical trials on GBM based on the assumption that this history will affect their survival outcomes. This practice may affect clinical trial accrual and limit the gathering of knowledge essential to the formulation of therapeutic options for this patient popul...
Ünal, İsmail Üstündağ, Ünsal V Ateş, Perihan S Eğilmezer, Gizem Alturfan, Ahmet A Yiğitbaşı, Türkan Emekli-Alturfan, Ebru
Published in
The International journal of neuroscience
Rotenone is a commonly used pesticide that inhibits complex I of the mitochondrial electron transport system. Rotenone exposed rats demonstrate many characteristics of Parkinson Disease (PD). Oxidative stress is one of the hallmarks of PD, being the major sources of ROS in the DA neurons. In recent years the strong connection between the intestinal...
Kong, Xianmin Tian, Shanshan Chen, Tao Huang, Yinghui
Published in
The International journal of neuroscience
The design of pattern that limit the hippocampal cells growth is an important explore for realizing a simplified artificial neuronal network in vitro. In this study, we examined the pattern in micro-fluidic chip to stipulate the hippocampal cells adhesion, growth and the formation of a functional neuronal network in vitro. Patch clamp recording tec...
Singh, Neha Vijayanti, Sheekha Saha, Lekha
Published in
The International journal of neuroscience
Purpose/Aim: Epilepsy is a complex, chronic neurological disorder characterized by increased and abnormal synchronization of neuronal electrical activity, which is manifested as seizures. It is associated with many comorbid conditions such as depression, anxiety, sleep disorder, psychiatric disorder etc., which consequently causes higher mortality ...
Song, Miyeoun Han, Maeum Kim Kwon, Yunhee
Published in
The International journal of neuroscience
Aucubin (ACB) is an iridoid glycoside with various biological activities. Previously, it is reported that ACB reduces cell survival and proliferation in many human tumors, whereas it facilitates cell survival and neuroprotection in damaged neuronal cells and disease models. However, its effects on cell survival in the non-proliferating or different...
Han, Jingzhe Ji, Ye Ma, Guomei Kang, Zhilei
Published in
The International journal of neuroscience
The persistent primitive hypoglossal artery (PPHA) is the second most common persistent carotid-vertebrobasilar anastomosis. We present a rare case of an 82-year-old woman who diagnosed as acute cerebral infarction three times in both the anterior and posterior circulation territories with a right-sided PPHA and ipsilateral carotid artery dissectio...
Anniwaer, Jianati Liu, Meng-Zhuang Xue, Ke-Dong Maimaiti, Abuduzhayier Xiamixiding, Aersilan
Published in
The International journal of neuroscience
Although hyperhomocysteinemia (Hhcy) is a risk factor for cerebral infarction, its effect on recurrent cerebral infarction is less-defined. We aimed to investigate the association of Hhcy and increased risk of recurrent cerebral infarct. From 2011-2013, we recruited 231 primary cerebral infarct patients that were divided to a Hhcy group (n = 105) a...
