Bandookwala, Maria Sengupta, Pinaki
Published in
The International journal of neuroscience
Reactive oxygen species are generated as a by-product of routine biochemical reactions. However, dysfunction of the antioxidant system or mutations in gene function may result in the elevated production of the pro-oxidant species. Modified endogenous molecules due to chemical interactions with increased levels of reactive oxygen and nitrogen specie...
Du, Yayun Liu, Xiaoli Zhu, Xilin Liu, Ying Wang, Xinru Wu, Xiaopan
Published in
The International journal of neuroscience
Amyloid plaques are the most important pathological hallmarks of Alzheimer's disease. The deposition of amyloid plaques will cause ER Stress. Activating Transcription Factor 6(ATF6) is a sensor of ER Stress. However, the role of ATF6 in Alzheimer's disease has not been reported yet. The levels of β-site APP-cleaving enzyme 1 (BACE1) and Aβ1-42 were...
Li, Yingjiao Wang, Cui Lian, Yajun Zhang, Haifeng Meng, Xianghe Yu, Mengyan Li, Yujuan Xie, Nanchang
Published in
The International journal of neuroscience
Mitochondrial Ca2+ overload is closely associated with seizure-induced neuronal damage. The mitochondrial calcium uniporter (MCU) plays a crucial role in regulating mitochondrial Ca2+ homeostasis. However, the role of the MCU in seizure-induced neuronal damage remains elusive. Materials and methods: In this study, the hippocampal neuronal culture (...
Virdi, Jasleen Kaur Bhanot, Amritansh Jaggi, Amteshwar Singh Agarwal, Neha
Published in
The International journal of neuroscience
The present study was undertaken to investigate the possible role of histidine-histamine pathway in the neuroprotective effects produced by L-carnosine hand in hand with ischemic postconditioning in the animal model of cerebral ischemia. Cerebral ischemia was induced in swiss albino mice by performing BCCAO surgery. Morris water-maze test was utili...
Zhang, Wen-Jun Xu, Jian Xiong, Mei-Juan Liu, Zeng-Xu Zhu, Zheng-Ming
Published in
The International journal of neuroscience
The purpose of this study was to determine the effect of microencapsulated olfactory ensheathing cells (MC-OECs) transplantation on neuropathic pain (NPP) caused by sciatic nerve injury in rats, and its relationship with the expression levels of P2X2 receptor (P2X2R) in the L4-5 spinal cord segment. Olfactory bulb tissue was removed from a healthy ...
Tang, Yi Liu, Yanqiu Li, Dan Guo, Dongmei Xing, Yi
Published in
The International journal of neuroscience
Cerebrotendinous xanthomatosis (CTX) is an inherited disorder associated with abnormal deposition of cholestenol in the brain and other tissues. Here we report a Chinese family with two affected members of CTX. Clinical data were collected. Gene analysis, MRI, neuropsychological assessments, and the biopsy of right Achilles tendon xanthoma were car...
Iwuchukwu, Ifeanyi Bui, Cuoung Hsieh, Billie Sabharwal, Vivek Mohammed, Alaa McGrade, Harold Biro, Erin Nguyen, Doan Sulaiman, Olawale
Published in
The International journal of neuroscience
The benefit of decompressive hemicraniectomy in patients with malignant acute ischemic stroke is well established, however its role in supratentorial intracerebral hemorrhages is unclear and evolving. Prior studies combined cortical and subcortical hemorrhages in their analysis despite their different natural history. Subcortical hematoma is associ...
Fontes, Rhailana Medeiros Marinho, Victor Carvalho, Valécia Rocha, Kaline Magalhães, Francisco Moura, Iris Ribeiro, Pedro Velasques, Bruna Cagy, Mauricio Gupta, Daya S
...
Published in
The International journal of neuroscience
This study investigated whether time-estimation task exposure influences the severity of Attention Deficit Hyperactivity Disorder (ADHD), as well as theta band activity in the dorsolateral prefrontal cortex and ventrolateral prefrontal cortex. Twenty-two patients with ADHD participated in a crossover experiment with a visual time-estimation task un...
Xiong, Jinbiao Cao, Yiyao Yang, Weidong Chen, Zhijuan Yu, Qing
Published in
The International journal of neuroscience
Since vagus nerve stimulation (VNS) was approved by the Food and Drug Administration (FDA). A number of studies show that VNS was effective to reduce seizure frequency. However, there was still some patients treated with VNS having poor or even no clinical effect. The purpose of the present review was to identify factors predicting the effect of VN...
Karthikeyan, Ramanujam Cardinali, Daniel P Shakunthala, Venkat Spence, David Warren Brown, Gregory M Pandi-Perumal, Seithikurippu R
Published in
The International journal of neuroscience
Several studies have established a positive relationship between sleep difficulties and symptomatology in ASD children. The rationale for this review is to describe and discuss the sleep difficulties, which are one of the significant complications associated with autism spectrum disorder (ASD). Many types of sleep disorders have been reported in AS...
