Syncytia formation by SARS‐CoV‐2‐infected cells
...Published in The EMBO Journal
The hSSB1 orthologue Obfc2b is essential for skeletogenesis but dispensable for the DNA damage response in vivo
Published in The EMBO Journal
Opposing activities of IFITM proteins in SARS‐CoV‐2 infection
...Published in The EMBO Journal
Interferon‐induced transmembrane proteins (IFITMs) restrict infections by many viruses, but a subset of IFITMs enhance infections by specific coronaviruses through currently unknown mechanisms. We show that SARS‐CoV‐2 Spike‐pseudotyped virus and genuine SARS‐CoV‐2 infections are generally restricted by human and mouse IFITM1, IFITM2, and IFITM3, us...
LRRK 2 regulates endoplasmic reticulum–mitochondrial tethering through the PERK ‐mediated ubiquitination pathway
Published in The EMBO Journal
Optimal sidestepping of intraflagellar transport kinesins regulates structure and function of sensory cilia
...Published in The EMBO Journal
α‐Actinin‐1 promotes activity of the L‐type Ca 2+ channel Ca v1.2
...Published in The EMBO Journal
Domain structure of secretin PulD revealed by limited proteolysis and electron microscopy.
Published in The EMBO journal
Secretins, a superfamily of multimeric outer membrane proteins, mediate the transport of large macromolecules across the outer membrane of Gram-negative bacteria. Limited proteolysis of secretin PulD from the Klebsiella oxytoca pullulanase secretion pathway showed that it consists of an N-terminal domain and a protease-resistant C-terminal domain t...
High resolution AFM topographs of the Escherichia coli water channel aquaporin Z.
Published in The EMBO journal
Aquaporins form a large family of membrane channels involved in osmoregulation. Electron crystallography has shown monomers to consist of six membrane spanning alpha-helices confirming sequence based predictions. Surface exposed loops are the least conserved regions, allowing differentiation of aquaporins. Atomic force microscopy was used to image ...
The Sir4 H‐ BRCT domain interacts with phospho‐proteins to sequester and repress yeast heterochromatin
Published in The EMBO Journal
Loss of the maintenance methyltransferase, xD nmt1, induces apoptosis in Xenopus embryos
Published in The EMBO Journal
