Kumar, Nikhil Singh, Mithalesh Kumar Singh, Lata Jha, Jayanti Pushker, Neelam Lomi, Neiwete Meel, Rachna Sen, Seema Kashyap, Seema
Published in
The British journal of ophthalmology
Increased pigmentation has been associated with cancer stem-cell-like behaviour and chemoresistance in uveal melanoma (UM) and cutaneous melanoma. Therefore, our present study determines the correlation between pigmentation and cancer stem cell markers in UM patients. Expression of PAX3, CD133, ABCG2, TRYP1, TRYP2 and microphthalmia-associated tran...
Zhang, Xiu Juan Zaabaar, Ebenezer French, Amanda Nicole Tang, Fang Yao Kam, Ka Wai Tham, Clement C Chen, Li Jia Pang, Chi Pui Yam, Jason C
Published in
The British journal of ophthalmology
Myopia has long been a global threat to public health. Timely interventions are likely to reduce the risk of vision-threatening complications. There are both established and rapidly evolving therapeutic approaches to slow myopia progression and/or delay its onset. The effective methods for slowing myopia progression include atropine eye-drops, defo...
Zhao, Lingyi Zhang, Bo Wang, Jingjing Yang, Jinliuxing Du, Linlin Wang, Tianxiao Xu, Xun He, Xiangui Chen, Jun
Published in
The British journal of ophthalmology
To evaluate the short-term effects of different sunlight exposure on fundus blood flow perfusion (BFP) after near work. In this parallel randomised controlled trial, 81 students aged 7-15 with spherical equivalent refraction between -2.00 and +3.00 diopters were randomly assigned to either a low-illuminance (4k lux) group (N=40) or high-illuminance...
Choudhary Balla, Shravya Ali, Mohammed Hasnat Tyagi, Mudit Basu, Soumyava
Published in
The British journal of ophthalmology
Tuberculosis (TB)-immunoreactivity, measured in vivo (tuberculin skin test (TST)) or in vitro (interferon gamma release assay (IGRA)), can be found in latent, active or even following clearance of TB infection. In this case-control study, we compared the systemic and ocular outcomes between patients with or without TB-immunoreactivity, who received...
Fink, David Julian Dell, Jennifer Heinz, Carsten Wintergerst, Maximilian W M Höller, Tobias Berger, Moritz Schmid, Matthias Boden, Karl Thomas Pleyer, Uwe Reitsamer, Herbert
...
Published in
The British journal of ophthalmology
The Treatment exit Options For non-infectious Uveitis (TOFU) registry documents disease courses for non-anterior non-infectious uveitis entities with and without treatment to generate more evidence for clinical management recommendations including treatment exit strategies. In this article, we present the participants' baseline characteristics afte...
Zeng, Danqi Yang, Yahan Tang, Yang Zhao, Lanqin Wang, Xun Yun, Dongyuan Chen, Wenben Shang, Yuanjun Xu, Andi Liao, Huipeng
...
Published in
The British journal of ophthalmology
To investigate the association of floor area ratio (FAR), an indicator of built environments, and myopia onset. This prospective cohort study recruited 136 753 children aged 6-10 years from 108 schools in Shenzhen, China at baseline (2016-2017). Refractive power was measured with non-cycloplegic autorefraction over a 2-year follow-up period. FAR wa...
Reid, Gerard Azuara-Blanco, Augusto
Published in
The British journal of ophthalmology
Katsimpris, Andreas Baumeister, Sebastian-Edgar Baurecht, Hansjörg Tatham, Andrew J Nolde, Michael
Published in
The British journal of ophthalmology
The association of central corneal thickness (CCT) with primary open-angle glaucoma (POAG) remains uncertain. Although several observational studies assessing this relationship have reported an inverse association between CCT and POAG, this could be the result of collider bias. In this study, we leveraged human genetic data to assess through Mendel...
Sharma, Namrata Venugopal, Renu Nagpal, Ritu K, Priyadarshini Verma, Kamna Verma, Kaushal K Biswas, N R Velpandian, Thirumurthy Sen, Seema Dwivedi, S N
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Published in
The British journal of ophthalmology
To evaluate the role of topical cyclosporine A 1% (CsA) as an adjuvant therapy in patients with acute Stevens-Johnson syndrome (SJS). This is a randomised controlled trial in which 44 patients (88 eyes) with acute SJS, presenting within 3 months from the onset of the disease, were enrolled and randomised. Group A (n=44 eyes) patients received treat...
Zhong, Pingting Yang, Shaopeng Liu, Riqian Zhu, Ziyu Zhang, Yongjie Cheng, Weijing Wang, Wei
Published in
The British journal of ophthalmology
The purpose is to investigate the association between handgrip strength (HGS) and the risk of future diabetic complications in multicountry cohorts. The association between HGS and diabetic complications was evaluated using cox models among 84 453 patients with pre-diabetes and diabetes from the UK Biobank with a 12-year follow-up. The association ...