Xue, Can Can Wang, Xiaofei Han, Ying Xiang Zhang, Qi Zhang, Chun Wang, Ya Xing Jonas, Jost B
Published in
The British journal of ophthalmology
To investigate the association between the backward configuration of the peripapillary sclera (PPS), measured as PPS angle (PPSA), and presence and extent of parapapillary gamma zone. Out of the population-based Beijing Eye Study 2011, we randomly selected individuals free of optic nerve and retinal diseases. With Spectralis optical coherence tomog...
Bosten, Jenny M Lawrance-Owen, Adam J Bargary, Gary Goodbourn, Patrick T Mollon, John D
Published in
The British journal of ophthalmology
Physiological anisocoria is an asymmetry of pupil size in the absence of pathology. Images of the pupils under standard illumination were collected in the course of a whole-genome association study of a range of visual functions in 1060 healthy adults. DNA for each participant was extracted from saliva samples. We found no relationship between anis...
Wu, Wei Xu, Jingjie Yin, Houfa Fu, Chenxi Yao, Ke Chen, Xiangjun
Published in
The British journal of ophthalmology
Nanophthalmos is a rare developmental, bilateral, sporadic or hereditary form of microphthalmos. In this study, the heterozygous variants c.781G>A and c.1066dup of the PRSS56 gene were identified in two patients with nanophthalmos. This study reports the clinical manifestation and the underlying pathogenic mechanism. Whole-exome sequencing was perf...
Nishida, Takashi Mahmoudinezhad, Golnoush Weinreb, Robert N Baxter, Sally L Eslani, Medi Liebmann, Jeffrey M Girkin, Christopher A Fazio, Massimo A M Zangwill, Linda Moghimi, Sasan
...
Published in
The British journal of ophthalmology
To investigate the relationship between smoking and smoking intensity, and the rate of retinal nerve fibre layer (RNFL) thinning in patients with primary open angle glaucoma (POAG). In this longitudinal study, patients with POAG who had at least 3 years of follow-up with a minimum of 5 visits of optical coherence tomography (OCT) were enrolled. The...
Cheng, Weijing Wang, Wei Song, Yunhe Lin, Fengbin Duan, Yongbo Xie, Liu Jin, Kai Weinreb, Robert N Zhang, Xiulan
Published in
The British journal of ophthalmology
To explore the relationship between choriocapillaris (CC) flow deficit percentage (FD%) and ganglion cell-inner plexiform layer (GCIPL) thickness in a population-based sample of non-glaucomatous eyes. This is a longitudinal cohort study and prospective cross-sectional study. Non-glaucoma Chinese subjects aged 18 years or older were enrolled. All pa...
Anguita, Rodrigo Charteris, David
Published in
The British journal of ophthalmology
Vision loss after detachment of the neurosensory retina is a complex process which is not fully understood. Clinical factors have been identified which contribute to loss of macular function after retinal detachment and laboratory studies have played an important role in understanding the cellular and subcellular pathological processes which underl...
Karlin, Justin Gai, Lisa LaPierre, Nathan Danesh, Kayla Farajzadeh, Justin Palileo, Bea Taraszka, Kodi Zheng, Jie Wang, Wei Eskin, Eleazar
...
Published in
The British journal of ophthalmology
To describe an artificial intelligence platform that detects thyroid eye disease (TED). Development of a deep learning model. 1944 photographs from a clinical database were used to train a deep learning model. 344 additional images ('test set') were used to calculate performance metrics. Receiver operating characteristic, precision-recall curves an...
Yasvoina, Marina Yang, Qian Woods, Sasha M Heeren, Tjebo Comer, Grant M A Egan, Catherine Fruttiger, Marcus
Published in
The British journal of ophthalmology
Invasion of pigmented cells into the retina occurs in retinal degenerative diseases, such as macular telangiectasia type 2 (MacTel) and retinitis pigmentosa (RP). These intraretinal pigmented cells may be derived from the retinal pigment epithelium (RPE), but differences and similarities between intraretinal pigmented cells and RPE have so far not ...
Maheshwari, Abhilasha Finger, Paul T Iacob, Codrin E
Published in
The British journal of ophthalmology
To describe the management of patients with occult anterior uveal melanomas presenting with extrascleral extension. Retrospective case series including five patients with small pigmented nodular mass on the episclera. Each lesion was documented by slit-lamp photography and measured with high-frequency ultrasound imaging (ultrasound biomicroscopy). ...
Lim, Elizabeth Wen Ling Chong, Crystal Chun Yuen Nusinovici, Simon Fenwick, Eva Lamoureux, Ecosse Luc Sabanayagam, Charumathi Cheng, Ching-Yu Tong, Louis
Published in
The British journal of ophthalmology
(1) To determine the independent association of dry eye symptoms with health-related quality of life (HRQoL) in the Singapore population and (2) to further investigate which factors mediate this association. In this cross-sectional study, 7707 participants were included. The presence of dry eye symptoms was defined as experiencing at least one out ...
