Qian, Jingui Huang, Wei Yang, Renhua Lam, Raymond H W Lee, Joshua E-Y
Published in
The Analyst
Acoustofluidic platforms for cell manipulation benefit from being contactless and label-free at potentially low cost. Particle concentration in a droplet relies on augmenting spatial asymmetry in the acoustic field, which is difficult to reproduce reliably. Etching periodic patterns into a chip to create acoustic band gaps is an attractive approach...
Dokuzparmak, Emre Brown, Kelly Dennany, Lynn
Published in
The Analyst
The abuse of methamphetamine (MA) is to date detected and subsequently verified through the monitoring of MA and its metabolites within biological specimens. Current approaches require complex sample purification strategies alongside significant analysis time. Given the high prevalence of MA within the global drug market, there remains a need for r...
Kadimisetty, Karteek Yin, Kun Roche, Aoife M Yi, Yanjie Bushman, Frederic D Collman, Ronald G Gross, Robert Feng, Liang Liu, Changchun
Published in
The Analyst
Rapid and efficient biological sample preparation and pretreatment are crucial for highly sensitive, reliable and reproducible molecular detection of infectious diseases. Herein, we report a self-powered, integrated sample concentrator (SPISC) for rapid plasma separation, pathogen lysis, nucleic acid trapping and enrichment at the point of care. Th...
Sudalaimani, S Sanjeev Kumar, K Esokkiya, A Suresh, C Giribabu, K
Published in
The Analyst
Putrescine and cadaverine are biogenic amines that serve as potential biomarkers for several types of cancers and monitoring food quality. Electrochemical sensing of putrescine and cadaverine by non-enzymatic routes remains a challenge because of their inertness at unmodified electrode surfaces and hence a liquid-liquid interface strategy has been ...
Shahhoseini, Fereshteh Langille, Evan A Azizi, Ali Bottaro, Christina S
Published in
The Analyst
Enhancing selectivity, reducing matrix effects and increasing analytical throughput have been the main objectives in the development of biological sample preparation techniques. A thin film molecularly imprinted polymer (MIP) is employed for extraction and analysis of tricyclic antidepressants (TCAs) as a model class of compounds in human plasma fo...
van Manen, Henk-Jan Gerretzen, Jan Smout, Martijn Postma, Geert Jansen, Jeroen J
Published in
The Analyst
Quantitative vibrational absorption spectroscopies rely on Beer's law relating spectroscopic intensities in a linear fashion to chemical concentrations. To address and clarify contrasting results in the literature about the difference between volume- and mass-based concentrations units used for quantitative spectroscopy on liquid solutions, we perf...
Attari, Farnoosh Hazim, Habibullah Zandi, Ashkan Mazarei, Zeinab Rafati, Hasan
Published in
The Analyst
One of the best strategies to circumvent drug resistance is the employment of nanocarriers. For the current study, we have employed a nanoemulsion formulation of paclitaxel (PTX) to bypass drug resistance in the MDA-MB-231 cell line and impedance sensing biosensors to determine the exact time that PTX-NE induced apoptosis. Our MTT results demonstra...
Sricharoen, Nontawat Sukmanee, Thanyada Pienpinijtham, Prompong Ekgasit, Sanong Kitahama, Yasutaka Ozaki, Yukihiro Wongravee, Kanet
Published in
The Analyst
The multivariate curve resolution-alternative least squares (MCR-ALS) algorithm was modified with sample insertion constraint to deconvolute the overlapping peaks in SERS spectra. The developed method was evaluated by the spectral data simulated using a Gaussian distribution function to generate two independent peaks corresponding to a capping agen...
Fernández-Ramos, M D Pageo-Cabrera, M Capitán-Vallvey, L F Pérez de Vargas-Sansalvador, I M
Published in
The Analyst
An inkjet printed membrane is presented as a colorimetric sensor for oxygen for use in smart packaging, in order to quickly inform the consumer about possible degradation reactions in modified atmosphere products (MAP). The colorimetric sensor is based on the redox dye, toluidine blue (TB), a sacrificial electron donor, glycerol, and, hydroxypropyl...
Jamalipour Soufi, Ghazaleh Iravani, Siavash Varma, Rajender S
Published in
The Analyst
Molecularly imprinted polymers (MIPs) have numerous applications in the sensing field, the detection/recognition of virus, the structure determination of proteins, drug delivery, artificial/biomimetic antibodies, drug discovery, and cell culturing. There are lots of conventional methods routinely deployed for the analysis/detection of viral infecti...
