Perrillo, R P Griffin, R DeSchryver-Kecskemeti, K Lander, J J Zuckerman, G R
Published in
The American journal of digestive diseases
Twenty patients with longstanding alcoholism and biopsy-proven alcoholic liver disease presented with marked elevation of serum alkaline phosphatase (in excess of four times the upper limit of normal). None had a past or present history to suggest pancreatitis or biliary tract disease, nor had any of these patients recently taken medication which c...
Accinni, L Brentjens, J R Albini, B Ossi, E O'Connell, D W Pawlowski, I B Andres, G A
Published in
The American journal of digestive diseases
The possible role of circulating immune complexes (IC) in the production gastrointestinal lesions was studied in rabbits with chronic serum sickness (CSS) induced by multiple daily injections of bovine serum albumin (BSA). All rabbits generating a marked antibody response developed IC glomerulonephritis. In approximately 50% of these rabbits granul...
Lee, J H Griffiths, W J Zantout, I Welsh, J D
Published in
The American journal of digestive diseases
Intestinal mucosa from 40 patients obtained by fiber-endoscopic biopsy was assayed for disaccharidases to determine suitability of this tissue for assay. The combined specimens from each patient provided 4.7-38.7 mg of tissue, adequate in all instances for duplicate determinations of protein, lactase, sucrase, and maltase. Tissue remained for assay...
Owyang, C Heath, H 3rd Sizemore, G W Go, V L
Published in
The American journal of digestive diseases
We compared the effects of exogenous pentagastrin and meal-stimulated gastrin on plasma immunoreactive calcitonin (iCT) in various studies of 13 normal adult men. Bolus intravenous injection of pentagastrin (0.5 microgram/kg) produced increases of iCT in 8 of 9 men. There was a linearly increasing response of iCT concentrations to increasing doses ...
Schulze, K Jabbari, M Murray, D
Published in
The American journal of digestive diseases
A 67-year-old white man presented with bloody diarrhea and passed a 22-cm long segment of full-thickness sigmoid colon following a barium enema. He had advanced peripheral and cerebral vascular disease and had undergone pelvic irradiation for a bladder cancer five years previously. He recovered uneventfully from the bowel sloughage. This was appare...
Angelin, B Einarsson, K Hellstrom, K
Published in
The American journal of digestive diseases
The kinetics of cholic acid (C) and chenodeoxycholic acid (CD) were studied in six patients with portal liver cirrhosis. The studies were conducted both before and after 5-6 weeks of treatment with cholestyramine (12 g/day). In keeping with previous observations, the pool size and formation of C showed subnormal values during the pretreatment perio...
Schwarts, S S Zeidler, A Moossa, A R Kuku, S F Rubenstein, A H
Published in
The American journal of digestive diseases
Ninety-nine patients suspected of having pancreatic carcinoma were studied prospectively for carbohydrate tolerance. Thirty-two patients were proven subsequently to have pancreatic carcinoma; the remainder served as a control group. There was an increased incidence of carbohydrate intolerance in patients with pancreatic carcinoma compared to the co...
Mok, H Y von Bergmann, K Grundy, S M
Published in
The American journal of digestive diseases
Spitz, R D Keren, D F Boitnott, J K Maddrey, W C
Published in
The American journal of digestive diseases
The probable etiology and outcome of bridging hepatic necrosis found on a liver biopsy performed within three months of the onset of clinical illness was evaluated in 42 consecutive patients with this finding. Eighteen of the patients (43%) had a probable drug etiology for their hepatitis. Ten patients had HBSAG-positive acute hepatitis. Fourteen p...
Rambaud, J C Modigliani, R Emonts, P Matuchansky, C Vidon, N Besterman, H Bernier, J J
Published in
The American journal of digestive diseases
The slow marker perfusion technique was used in five patients with the Zollinger-Ellison syndrome in order to determine the basal and postcibal flow rates of fluids passing the duodenojejunal junction and distal ileum, and the composition of those fluids. Fecal water and electrolyte excretions were also measured. The 24-hr outputs at the ligament o...
