Perrillo, R P Griffin, R DeSchryver-Kecskemeti, K Lander, J J Zuckerman, G R
Published in
The American journal of digestive diseases
Twenty patients with longstanding alcoholism and biopsy-proven alcoholic liver disease presented with marked elevation of serum alkaline phosphatase (in excess of four times the upper limit of normal). None had a past or present history to suggest pancreatitis or biliary tract disease, nor had any of these patients recently taken medication which c...
Lee, J H Griffiths, W J Zantout, I Welsh, J D
Published in
The American journal of digestive diseases
Intestinal mucosa from 40 patients obtained by fiber-endoscopic biopsy was assayed for disaccharidases to determine suitability of this tissue for assay. The combined specimens from each patient provided 4.7-38.7 mg of tissue, adequate in all instances for duplicate determinations of protein, lactase, sucrase, and maltase. Tissue remained for assay...
Mok, H Y von Bergmann, K Grundy, S M
Published in
The American journal of digestive diseases
Spitz, R D Keren, D F Boitnott, J K Maddrey, W C
Published in
The American journal of digestive diseases
The probable etiology and outcome of bridging hepatic necrosis found on a liver biopsy performed within three months of the onset of clinical illness was evaluated in 42 consecutive patients with this finding. Eighteen of the patients (43%) had a probable drug etiology for their hepatitis. Ten patients had HBSAG-positive acute hepatitis. Fourteen p...
O'Dorisio, T M Spaeth, J T Martin, E W Jr Sirinek, K R Thomford, N R Mazzaferri, E L Cataland, S
Published in
The American journal of digestive diseases
Serum gastric inhibitory polypeptide was measured in dogs prepared with Heidenhain pouches and Mann-Bollman fistulae following the intraduodenal (ID) infusion of isotonic saline, 20% glucose, or 20% mannitol. Following ID 20% glucose, serum GIP concentrations rose significantly (P less than 0.05) between 30 and 120 min and there was a significant i...
Braverman, D Bogoch, A
Published in
The American journal of digestive diseases
Harty, R F Steinberg, W M
Published in
The American journal of digestive diseases
Accinni, L Brentjens, J R Albini, B Ossi, E O'Connell, D W Pawlowski, I B Andres, G A
Published in
The American journal of digestive diseases
The possible role of circulating immune complexes (IC) in the production gastrointestinal lesions was studied in rabbits with chronic serum sickness (CSS) induced by multiple daily injections of bovine serum albumin (BSA). All rabbits generating a marked antibody response developed IC glomerulonephritis. In approximately 50% of these rabbits granul...
Rambaud, J C Modigliani, R Emonts, P Matuchansky, C Vidon, N Besterman, H Bernier, J J
Published in
The American journal of digestive diseases
The slow marker perfusion technique was used in five patients with the Zollinger-Ellison syndrome in order to determine the basal and postcibal flow rates of fluids passing the duodenojejunal junction and distal ileum, and the composition of those fluids. Fecal water and electrolyte excretions were also measured. The 24-hr outputs at the ligament o...
Schwarts, S S Zeidler, A Moossa, A R Kuku, S F Rubenstein, A H
Published in
The American journal of digestive diseases
Ninety-nine patients suspected of having pancreatic carcinoma were studied prospectively for carbohydrate tolerance. Thirty-two patients were proven subsequently to have pancreatic carcinoma; the remainder served as a control group. There was an increased incidence of carbohydrate intolerance in patients with pancreatic carcinoma compared to the co...
