Yen, Pei-Tzu Huang, Shang-En Hsu, Jong-Hau Kuo, Cheng-Hsiang Chao, Yu-Ying Wang, Lung-Shuo Yeh, Jwu-Lai
Published in
The American journal of Chinese medicine
During menopause, the sharp decline in estrogen levels leads to an increased risk of cardiovascular disease in women. The inflammatory response and oxidative stress are reportedly involved in the development of cardiovascular disorders postmenopause. In this study, we evaluated the cardioprotective effects of puerarin, a phytoestrogen derived from ...
Dong, Li Shen, Zhijie Chi, Hao Wang, Yingjie Shi, Zhaofeng Fang, Hongjun Yang, Yanling Rong, Jingfeng
Published in
The American journal of Chinese medicine
Vascular recanalization is the essential procedure in which severe coronary artery stenosis is diagnosed. However, the blood flow recovery associated with this procedure may cause myocardial ischemia-reperfusion injury (MIRI), which aggravates heart failure. Unfortunately, the mechanism of MIRI has historically been poorly understood. As we now kno...
Li, Yuangeng Yu, Ping Fu, Wenwen Wang, Shuo Zhao, Wenjun Ma, Yue Wu, Yi Cui, Heming Yu, Xiaofeng Fu, Li
...
Published in
The American journal of Chinese medicine
Carbon tetrachloride (CCl4)-induced lipid peroxidation associated with hepatic oxidative stress and cell death is an important mechanism of acute liver injury (ALI). Ginsenoside Rd is considered an active ingredient of ginseng. Evidence suggests that ginsenoside Rd may improve ischaemic stroke, nerve damage, cancer and other diseases involving apop...
Lin, Shumeng Wen, Jing Xu, Xiao Shi, Jiamin Zhang, Wen Zheng, Tiansheng Hou, Yaqin Zhang, Yanfei Li, Ziye Wang, Kai
...
Published in
The American journal of Chinese medicine
Lung cancer is the most commonly diagnosed cancer and the leading cause of cancer death worldwide. Amygdalin, a natural compound commonly distributed in plants of the Rosaceae species, owns anticancer activity, less side effects, wide source, and relatively low price. Although the apoptosis is a central process activated by amygdalin in cancer cell...
Zheng, Shihao Xue, Tianyu Wang, Bin Guo, Haolin Liu, Qiquan
Published in
The American journal of Chinese medicine
Ulcerative colitis (UC) is a common clinical inflammatory bowel disease characterized by repeated attacks, difficult treatment, and great harm to the physical and mental health of the patients. The occurrence and development of UC were closely related to the physiological and pathological processes, such as intestinal inflammatory reaction, oxidizi...
Ding, Chao Li, Yuze Sun, Yu Wu, Ying Wang, Fengrui Liu, Chenwang Zhang, Huawei Jiang, Yi Zhang, Dongdong Song, Xiaomei
...
Published in
The American journal of Chinese medicine
Sinomenium acutum is the dry stem of Sinomenium acutum (Thunb.) Rehd et Wils. (S. acutum) and Sinomenium acutum (Thunb.) Rehd. et Wils. var. cinereum Rehd. et Wils and is mainly distributed in China and Japan. As a traditional Chinese medicine (TCM) for dispelling wind and dampness in China, it is widely distributed and has a long history of drug u...
Wang, Dong-Sheng Wang, Jia-Mei Zhang, Fu-Rui Lei, Feng-Jie Wen, Xin Song, Jia Sun, Guang-Zhi Liu, Zhi
Published in
The American journal of Chinese medicine
Our previous study has revealed that malonyl-ginsenosides from Panax ginseng (PG-MGR) play a crucial role in the treatment of T2DM. However, its potential mechanism was still unclear. In this study, we investigated the anti-diabetic mechanisms of action of PG-MGR in high fat diet-fed (HFD) and streptozotocin-induced diabetic mice and determined the...
Si, Yuan-Cheng Ren, Chen-Chen Zhang, Er-Wei Kang, Zhao-Xia Mo, Xi-Ya Li, Qing-Qing Chen, Bo
Published in
The American journal of Chinese medicine
Acupuncture has been used to treat numerous diseases such as obesity in China for thousands of years. Several mechanisms of acupuncture on obesity have been surveyed based on metabolomics, but the effects of acupuncture on the alterations in the gut flora are still unclear. In this study, an integrated approach based on 16S rRNA gene sequencing com...
Qiu, Miao Peng, Jiao Deng, Huan Chang, Yaoyao Hu, Die Pan, Weidong Wu, Haiqiang Xiao, Haitao
Published in
The American journal of Chinese medicine
Type 2 diabetes mellitus (T2DM) has become a universal and chronic global public health concern and causes multiple complex complications. In order to meet the rapidly growing demand for T2DM treatment, increased research has been focused on hypoglycemic drugs. Cyclocarya paliurus (Batal.) Iljinsk is the only living species of the genus Cyclocarya ...
Wu, Guo-Dong Pan, An Zhang, Xu Cai, Yuan-Yuan Wang, Qi Huang, Feng-Qing Alolga, Raphael N Li, Jing Qi, Lian-Wen Liu, Qun
...
Published in
The American journal of Chinese medicine
Dysbiotic gut microbiota has been identified as a primary mediator of inherent inflammation that underlies the pathogenesis of obesity. Cordyceps comprises the larval body and the stroma of Cordyceps sinensis (BerK.) Sacc. parasiting on Hepialidae larvae of moths (H. pialusoberthur) with potent metabolic regulation functions. The underlying anti-ob...
