Published in Terapevticheskiĭ arkhiv
The paper gives an update on the role of the microbiota in the maintenance of human health and in the pathogenesis of diseases. There is evidence for the efficacy and safety of probiotics in the treatment and prevention of diarrhea of various genesis. The place of linex in the therapy of diarrhea syndrome is discussed on the basis of the results of...
Published in Terapevticheskiĭ arkhiv
The patients' age of gout onset does not affect substantial differences in the clinical features of gout with its comparable duration in the young and elderly patients. The main clinical features of gout are unique to both young and elderly patients. Cardiovascular diseases are more common at gout onset in the elderly.
Published in Terapevticheskiĭ arkhiv
The paper describes a clinical case of the efficacy of a fixed-dose combination of perindopril and amlodipine used in a hypertensive patient. It shows its clinical effectiveness with no impact on blood lipid and glucose levels. 24-hour blood pressure monitoring revealed a reduction in daily blood pressure, including its variability, in pulse wave p...
Published in Terapevticheskiĭ arkhiv
The made prediction scale allows the patients with STEMI to be allocated to groups at low, moderate, high risks for PO during a year. Evaluation of the prognostic efficiency of the new scale versus the known scales PAMI, CADILLAC, and TIMI ST elevation, by plotting the ROC curve and estimating the area under the latter, demonstrated the high predic...
Published in Terapevticheskiĭ arkhiv
The paper shows the value of chronic kidney disease as a population-wide determinant of vascular dementia, including moderate cognitive impairments. It discusses the role of risk factors of cardiovascular events, including those associated with chronic kidney disease, in the development of vascular dementia and moderate cognitive impairments.
Published in Terapevticheskiĭ arkhiv
Published in Terapevticheskiĭ arkhiv
Autoimmune polyglandular syndromes (APS) are an autoimmune involvement of two or more endocrine glands, which are characterized by multiple organ dysfunction. Four major types of APS are presently identified. There are APS types 2, 3, and 4 in adults. There are also latent and incomplete forms of adult-onset APS, the prevalence of which in the popu...
Published in Terapevticheskiĭ arkhiv
The review gives the results of a many-sided study of the basic properties of the therapeutic molecule of azoximer bromide (polyoxidonium). It analyzes our experience with the immunomodulator used to treat acute respiratory infections. Polyoxidonium has marked immunomodulatory (including interferon-producing) activity and a nonspecific protective e...
Published in Terapevticheskiĭ arkhiv
The literature review gives current views on the treatment of Helicobacter pylori infection. The rising antibiotic resistance of H. pylori in the first decade of the 21st century entailed the decreased efficiency of common eradication therapy (ET) regimens, by determining the higher interest in this problem. The paper summarizes data on the efficie...
Published in Terapevticheskiĭ arkhiv
