Published in Talanta
Mitochondrial fusion is essential to maintain genomic stability and physiological functions of mitochondria. Since mitochondrial fusion and fission work in concert to regulate mitochondrial morphology and functions, it has been challenging to quantitatively measure the direct roles of mitochondrial fusion in apoptosis and cancer progression. Here, ...
Published in Talanta
Protein MALDI imaging mass spectrometry (MALDI-IMS) holds a great promise to acquire spatial distribution information of proteins on biological tissue, but it suffers from the small number of proteins detected by direct MALDI-IMS detection. Ionic surfactants have been extensively used for protein extraction to improve the number of proteins detecte...
Published in Talanta
An ultra-small and highly efficient spectral-detection system for four emission points was developed by integrating an injection-molded-plastic four-lens array, a seven-dichroic-mirror array, and an image sensor as one device. The seven-dichroic-mirror array was further miniaturized compared to our previous four-dichroic-mirror array by measures in...
Published in Talanta
The mycotoxin ochratoxin A (OTA) is a secondary metabolite derived from multiple Aspergillus and Penicillium strains. The development of a rapid, sensitive, and simple method for OTA detection is important to ensure food biosafety and safeguard public health. In this study, we designed a highly specific and sensitive assay for the detection of OTA ...
Published in Talanta
Controlled Potential Coulometry (CPC) is generally regarded as one of the most accurate analytical methods available for the quantification of plutonium (Pu) in acidic aqueous solutions. With a growing use of mixed oxide nuclear fuel, there has been an interest in the technique's applicability to the analysis of Pu in the presence of uranium (U). E...
Published in Talanta
Quantitative localization of metals in biological tissue sections is critical to obtain insight into metal toxicity mechanisms or their beneficial characteristics. This study presents the development of a quantitative LA-ICP MS bioimaging methodology based on the polymer film strategy and internal standardization. To maximize the number of elements...
Published in Talanta
The increased attraction of biological volatile compounds has opened the route to a wide variety of sampling techniques, amongst which trap tubes packed with adsorbent materials are commonly used. Many types of adsorbent materials are available and the choice of the adsorbent can impact the obtained results in untargeted analysis. Therefore, a prop...
Published in Talanta
It was extremely urgent to develop some simultaneous and sensitive biosensors for detecting multiplex serum tumor markers (TMs) for early screening of cancers. Herein, a multiplex assay was developed based on the DNA-LaMnO3 (DNA-LMO) perovskite encoded probes and targets mediated competitive replacement strategy. Alpha fetoprotein (AFP), carcinoemb...
Published in Talanta
In this work, a three-dimensional mesoporous graphene (3D-MG) prepared by microwave-assisted method was used as both the adsorbent and the matrix of SALDI-TOF MS for polyphenols analysis in biological samples. The outstanding microstructure of 3D-MG made it sensitive in small molecule analysis with low background interference and able to enrich tra...
Published in Talanta
An online separation and preconcentration method, employing a lab-on-valve system using solid phase extraction, followed by inductively coupled plasma tandem mass spectrometry (ICP-MS/MS), was developed for the analysis of 90Sr. The 90Sr was separated from 90Zr, an isobaric interference present at high concentrations in many samples, and other matr...
