Sutton, Whitney Genberg, Becky Prescott, Jason D Segev, Dorry L Zeiger, Martha A Bandeen-Roche, Karen Mathur, Aarti
Published in
Surgery
Prior studies demonstrated that older adults tend to undergo less surgery for thyroid cancer. Our objective was to use a discrete choice experiment to identify factors influencing surgical decision-making for older adults with thyroid cancer. Active and candidate members of the American Association of Endocrine Surgeons were invited to participate ...
Seib, Carolyn D Meng, Tong Suh, Insoo Cisco, Robin M Lin, Dana T Morris, Arden M Trickey, Amber W Kebebew, Electron
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Surgery
Primary hyperparathyroidism is associated with substantial morbidity, including osteoporosis, nephrolithiasis, and chronic kidney disease. Parathyroidectomy can prevent these sequelae but is poorly utilized in many practice settings. We performed a retrospective cohort study using the national Optum de-identified Clinformatics Data Mart Database. W...
Wonn, Sarah M Limbach, Kristen E Pommier, SuEllen J Ratzlaff, Anna N Leon, E J McCully, Belinda H Pommier, Rodney F
Published in
Surgery
This study determines how much cytoreduction for small bowel neuroendocrine tumors with peritoneal carcinomatosis and liver metastases can be achieved and the corresponding survival benefits of different levels of clearance. Records of patients with small bowel neuroendocrine tumors with peritoneal carcinomatosis were reviewed and scored using the ...
Tran, Catherine G Scott, Aaron T Li, Guiying Sherman, Scott K Ear, Po Hien Howe, James R
Published in
Surgery
Patients with pancreatic neuroendocrine tumors often present with metastases, which reduce survival. Molecular features associated with pancreatic neuroendocrine tumor tumorigenesis have been reported, but mechanisms of metastasis remain incompletely understood. RNA sequencing was performed on primary and metastatic pancreatic neuroendocrine tumors...
Subramanian, Chitra Gorney, Rebecca Wang, Ton Ge, Derek Zhang, Nina Zuo, Ang Blagg, Brian S J Cohen, Mark S
Published in
Surgery
Patients with advanced differentiated thyroid cancer develop resistance to lenvatinib treatment from metabolic dysregulation. Heat shock protein 90 is a molecular chaperone that plays an important role in glycolysis and metabolic pathway regulation. We hypothesize that lenvatinib-resistant differentiated thyroid cancer cells will have an increased ...
Thiesmeyer, Jessica W Limberg, Jessica Ullmann, Timothy M Stefanova, Dessislava Bains, Sarina Beninato, Toni Zarnegar, Rasa Fahey, Thomas J 3rd Finnerty, Brendan M
Published in
Surgery
This study aimed to identify whether multikinase inhibitor approval for medullary thyroid carcinoma was associated with changes in systemic therapy administration or overall survival. The National Cancer Database was queried for advanced medullary thyroid carcinoma patients. Clinicopathologic comparisons were performed between premultikinase inhibi...
Ria, Roberto Prete, Francesco Melaccio, Assunta Di Meo, Giovanna Saltarella, Ilaria Solimando, Antonio G Gurrado, Angela Ferraro, Valentina Pasculli, Alessandro Sgaramella, Lucia I
...
Published in
Surgery
Circulating angiogenic factors have been associated with clinical outcomes of papillary thyroid carcinoma, although they may also be released in the context of benign multinodular goiter. We sought to investigate the effect of thyroidectomy on the activity and importance of multiple circulating angiogenic factors in papillary thyroid carcinoma and ...
Fung, Matrix Man Him Lang, Brian Hung-Hin
Published in
Surgery
Early recognition of postoperative vocal cord palsy enhances postoperative care. Translaryngeal ultrasonography can assess vocal cord function accurately and noninvasively, but it is unclear whether it is feasible or accurate when done immediately after extubation in the recovery room owing to possible interference from laryngeal swelling. This stu...
Craig, Steven Khalil, Moosa Eszlinger, Markus Itani, Doha Koebel, Martin Koro, Konstantin Minoo, Parham Ogilvie, Travis Stewardson, Paul Teman, Carolin
...
Published in
Surgery
Classification of thyroid follicular neoplasms can be challenging for pathologists. Introduction of noninvasive follicular thyroid neoplasms with papillary-like nuclear features, the utilization of immunohistochemistry, and molecular analysis are all thought to be valuable diagnostic adjuncts. Our aim was to determine whether interobserver variabil...
Thiesmeyer, Jessica W Ullmann, Timothy M Greenberg, Jacques Williams, Nicholas T Limberg, Jessica Stefanova, Dessislava Beninato, Toni Finnerty, Brendan M Vignaud, Timothée Leclerc, Julie
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Published in
Surgery
We aimed to compare the predictive performance of three distinct clinical models purported to predict the resolution of aldosteronoma-associated hypertension after adrenalectomy. A tri-institutional database of aldosteronoma patients who underwent adrenalectomy between 2004 and 2019 was retrospectively reviewed. The three models of interest incorpo...