Zhang, Ai Sokolova, Irina Domissy, Alain Davis, Joshua Rao, Lee Hana Utami, Kagistia Wang, Yanling Hagerman, Randi J Pouladi, Mahmoud A Sanna, Pietro
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Published in
Stem cells translational medicine
Fragile X Syndrome (FXS), the leading monogenic cause of intellectual disability and autism spectrum disorder, is caused by expansion of a CGG trinucleotide repeat in the 5'-UTR of the Fragile X Mental Retardation-1 (FMR1) gene. Epigenetic silencing of FMR1 results in loss of the Fragile X Mental Retardation Protein (FMRP). Although most studies to...
Chen, Zhihong Liu, Liyong Chen, Yunhua Liu, Minjie Peng Xiang, Andy Deng, Chunhua Jiang, Mei Hua
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Stem cells translational medicine
Interstitial cystitis (IC) is a bladder syndrome of unclear etiology with no generally accepted treatment. Growing evidence suggest that periostin (POSTN) is an important homeostatic component in the tissue repair and regeneration in adulthood, but its function in urinary bladder regeneration is still unknown. Here we investigate whether POSTN is i...
Kim, Jun-Ho Kim, Kang-Il Yoon, Wan Keun Song, Sang-Jun Jin, Wook
Published in
Stem Cells Translational Medicine
Graphical Abstract
Atala, Anthony
Published in
Stem Cells Translational Medicine
Ma, Ling Wei, Xiaowei Ma, Wei Liu, Yusi Wang, Yanfu He, Yiwen Jia, Shanshan Wang, Yu Luo, Wenting Liu, Dan
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Published in
Stem cells translational medicine
Spinal bifida aperta (SBA) is a congenital malformation with a high incidence. Bone marrow mesenchymal stem cell (BMSC) transplantation has the potential to repair the structure of damaged tissues and restore their functions. This is an optional treatment that can be used as a supplement to surgery in the treatment of SBA. However, the application ...
Kim, Kang-Il Lee, Woo-Suk Kim, Jun-Ho Bae, Jung-Kwon Jin, Wook
Published in
Stem Cells Translational Medicine
Graphical Abstract
Yi, Junzhi Zhang, Jiayan Zhang, Qin Chen, Xuri Qi, Rujie Liang, Renjie Wang, Ying Wang, Fei Zhong, Yuliang Zhang, Xianzhu
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Published in
Stem Cells Translational Medicine
Graphical Abstract
Rozanska, Agata Cerna-Chavez, Rodrigo Queen, Rachel Collin, Joseph Zerti, Darin Dorgau, Birthe Beh, Chia Shyan Davey, Tracey Coxhead, Jonathan Hussain, Rafiqul
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Stem cells translational medicine
Retinoblastoma (Rb) is a childhood cancer of the developing retina, accounting for up to 17% of all tumors in infancy. To gain insights into the transcriptional events of cell state transitions during Rb development, we established 2 disease models via retinal organoid differentiation of a pRB (retinoblastoma protein)-depleted human embryonic stem ...
Reuther, Susanne Floegel, Kathrin Ceusters, Gunther Albertini, Veronica Baran, Jakub Dempke, Wolfram
Published in
Stem Cells Translational Medicine
Saito, Yuki Miyajima, Maki Yamamoto, Sena Miura, Norihiro Sato, Tsukasa Kita, Arisa Ijima, Shogo Fujimiya, Mineko Chikenji, Takako S
Published in
Stem Cells Translational Medicine
Graphical Abstract
