Srivilai, Jukkarin Nontakhot, Kanjana Nutuan, Thanawan Waranuch, Neti Khorana, Nantaka Wisuthiprot, Wudtichai Scholfield, C. Norman Champachaisri, Katechan Ingkaninan, Kornkanok
Published in
Skin Pharmacology and Physiology
Background: Sesquiterpenes in Curcuma aeruginosa Roxb. inhibit steroid 5α-reductase and dihydrotestosterone production, and reverse androgenic alopecia. This study sought to show that a high sesquiterpene C. aeruginosa extract (CA-ext) retards axillary hair growth in women. Methods: Thirty women (age 20–52 years) were recruited into a 12-week, doub...
Liu, Wei Pan, Xiaochuan Vierkötter, Andrea Guo, Qun Wang, Xuying Wang, Qiaowei Seité, Sophie Moyal, Dominique Schikowski, Tamara Krutmann, Jean
...
Published in
Skin Pharmacology and Physiology
Background/Aims: There is increasing evidence that exposure to air pollutants, including particulate matter (PM2.5, PM10), nitrogen dioxide (NO2), and sulfur dioxide (SO2), might aggravate preexisting skin diseases such as eczema and urticaria. Here we investigated if a possible link exists between air pollution and acne vulgaris. We assessed the a...
Zeka, Keti Ruparelia, Ketan C. Sansone, Claudia Macchiarelli, Guido Continenza, Maria Adelaide Arroo, Randolph R.J.
Published in
Skin Pharmacology and Physiology
Saffron extracts have a long history of application as skin protectant, possibly due to their ability to scavenge free radicals. In this work, the performance of a hydrogel enriched with antioxidant compounds isolated from saffron crocus (Crocus sativus L.) petals was tested. These hydrogels could be considered as new drug delivery system. Hydrogel...
Lademann, Jürgen Knorr, Fanny Patzelt, Alexa Meinke, Martina C. Richter, Heike Krutmann, Jean Rühl, Eckart Doucet, Olivier
Published in
Skin Pharmacology and Physiology
Background/Aims: Airborne pollutants, such as nano-sized soot particles, are increasingly being released into the environment as a result of growing population densities and industrialization. They can absorb organic and metal compounds with potential biological activity, such as polycyclic aromatic hydrocarbons and airborne pollen allergens. Local...
Umar, Meenakshi Sastry, Konduru S. Al Ali, Fatima Al-Khulaifi, Moza Wang, Ena Chouchane, Aouatef I.
Published in
Skin Pharmacology and Physiology
Background: Vitamin D is a secosteroid, which was initially known for its skeletal role; however, in recent years, its functions in different organs have been increasingly recognized. In this review, we will provide an overview of vitamin D functions in the skin physiology with specific focus on its role in certain inflammatory skin conditions such...
Fernandes, Ana R. Santos, Ana C. Sanchez-Lopez, Elena Kovačević, Andjekla B. Espina, Marta Calpena, Ana C. Veiga, Francisco J. Garcia, Maria L. Souto, Eliana B.
Published in
Skin Pharmacology and Physiology
Neoplastic skin lesions are multifocal, diffuse skin infiltrations of particular relevance in the differential diagnosis of ulcerative, nodular, or crusting skin lesions. Nonmelanoma skin cancers (NMSCs), namely, basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and also actinic keratosis (AK), are the most common malignant tumors in human...
Kramer, Axel Dissemond, Joachim Kim, Simon Willy, Christian Mayer, Dieter Papke, Roald Tuchmann, Felix Assadian, Ojan
Published in
Skin Pharmacology and Physiology
Wound antisepsis has undergone a renaissance due to the introduction of highly effective wound-compatible antimicrobial agents and the spread of multidrug-resistant organisms (MDROs). However, a strict indication must be set for the application of these agents. An infected or critically colonized wound must be treated antiseptically. In addition, s...
Hołyńska-Iwan, Iga Dziembowska, Inga Smyk, Paulina Lampka, Magdalena Olszewska-Słonina, Dorota
Published in
Skin Pharmacology and Physiology
Acute, adverse skin effects to capsaicin can be activated by inhibition of sodium transport not only in nociceptive neurons, but also in keratinocytes. The aim of the current study was to describe and compare immediate (15 s) and prolonged (30 min) effects of capsaicin on epidermal (not neural) sodium transport using a rabbit skin model. Skin fragm...
Bassino, Eleonora Gasparri, Franco Munaron, Luca
Published in
Skin Pharmacology and Physiology
Background: Acne vulgaris is a common skin defect, usually occurring during adolescence, but often it can persist in adults leaving permanent face scarring. Acne is usually treated with topical drugs, oral antibiotics, retinoids, and hormonal therapies, but medicinal plants are increasingly employed. Objective: To investigate the protective role of...
Andréo-Filho, Newton Bim, Antonio Vinicius Kosiski Kaneko, Telma Mary Kitice, Nidia Ayumi Haridass, Isha N. Abd, Eman Santos Lopes, Patricia Thakur, Sachin S. Parekh, Harendra S. Roberts, Michael S.
...
Published in
Skin Pharmacology and Physiology
The use of sunscreen products is widely promoted by schools, government agencies, and health-related organizations to minimize sunburn and skin damage. In this study, we developed stable solid lipid nanoparticles (SLNs) containing the chemical UV filter octyl methoxycinnamate (OMC). In parallel, we produced similar stable SLNs in which 20% of the O...
