Han, A Reum Moon, Tae Kwon Kang, Im Kyeung Yu, Dae Bong Kim, Yechan Byon, Cheolhwan Park, Sujeong Kim, Hae Lin Kim, Hae Lin Lee, Kyoung Jin
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Published in
BMB reports
Adult hippocampal neurogenesis plays a pivotal role in maintaining cognitive brain function. However, this process diminishes with age, particularly in patients with neurodegenerative disorders. While small, non-coding microRNAs (miRNAs) are crucial for hippocampal neural stem (HCN) cell maintenance, their involvement in neurodegenerative disorders...
Park, HyoJin Kaang, Bong-Kiun
Published in
BMB reports
Memory allocation, which determines where memories are stored in specific neurons or synapses, has consistently been demonstrated to occur via specific mechanisms. Neuronal allocation studies have focused on the activated population of neurons and have shown that increased excitability via cAMP response element-binding protein (CREB) induces a bias...
Fragopoulou, Elizabeth Petsini, Filio Choleva, Maria Detopoulou, Maria S Arvaniti, Olga Kallinikou, Eftyhia Sakantani, Eleni Tsolou, Ageliki Nomikos, Tzortzis Samaras, Yiannis
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Published in
Molecules (Basel, Switzerland)
Inflammation, thrombosis and oxidative stress are rarely studied together when wine's biological activity is concerned; hence the existing literature lacks a holistic point of view in the biological outcome. The scope of the present study is to parallel evaluate the effect of wine extracts on those mechanisms. Ten wine varieties and two different e...
Golovko, Victor V. Kamaev, Oleg Sun, Jiansheng Jillings, Chris J. Gorel, Pierre Vazquez-Jauregui, Eric
The paper describes a system and experimental procedure that use integrating passive detectors, such as thermoluminescent dosimeters (TLDs), for the measurement of ultra-low-level ambient dose equivalent rate values at the underground SNOLAB facility located in Sudbury, Ontario, Canada. Because these detectors are passive and can be exposed for rel...
Fondo-Ferreiro, Pablo Candal-Ventureira, David González-Castaño, Francisco Javier Gil-Castiñeira, Felipe
Vehicle automation is driving the integration of advanced sensors and new applications that demand high-quality information, such as collaborative sensing for enhanced situational awareness. In this work, we considered a vehicular sensing scenario supported by 5G communications, in which vehicle sensor data need to be sent to edge computing resourc...
Kim, Soon-Bin Hwang, Soonjae Cha, Ji-Young Lee, Ho-Jae
Published in
International journal of molecular sciences
Programmed death ligand 1 (PD-L1) plays a pivotal role in cancer immune evasion and is a critical target for cancer immunotherapy. This review focuses on the regulation of PD-L1 through the dynamic processes of ubiquitination and deubiquitination, which are crucial for its stability and function. Here, we explored the intricate mechanisms involving...
Révész, Csaba Kaucsár, Tamás Godó, Mária Bocskai, Krisztián Krenács, Tibor Mócsai, Attila Szénási, Gábor Hamar, Péter
Published in
International journal of molecular sciences
Upregulation of free radical-generating NADPH oxidases (NOX), xanthine oxidoreductase (XOR), and neutrophil infiltration-induced, NOX2-mediated respiratory burst contribute to renal ischemia-reperfusion injury (IRI), but their roles may depend on the severity of IRI. We investigated the role of NOX, XOR, and neutrophils in developing IRI of various...
Hendricks, Linda A J Verbeek, Katja C J Schuurs-Hoeijmakers, Janneke H M Mensenkamp, Arjen R Brems, Hilde de Putter, Robin Anastasiadou, Violetta C Villy, Marie-Charlotte Jahn, Arne Steinke-Lange, Verena
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Published in
Cancers
Females with PTEN Hamartoma Tumor Syndrome (PHTS) have breast cancer risks up to 76%. This study assessed associations between breast cancer and lifestyle in European female adult PHTS patients. Data were collected via patient questionnaires (July 2020-March 2023) and genetic diagnoses from medical files. Associations between lifestyle and breast c...
D'Silva, Mizelle Cho, Jai-Young Han, Ho-Seong Yoon, Yoo-Seok Lee, Hae-Won Lee, Bo-Ram Kang, Mee-Young Park, Ye-Shong Kim, Jin-Ju
Published in
Cancers
Achieving textbook outcomes (TOs) improves the short-term and long-term performance of a hospital. Our objective was to assess TOs in the laparoscopic liver resection (LLR) of tumors in the PS (posterosuperior) section of the liver and identify the impact of the learning curve. We conducted a retrospective cohort study analyzing patients who underw...
Staub-Bartelt, Franziska Suresh Babu, Marian Preetham Szelényi, Andrea Rapp, Marion Sabel, Michael
Published in
Cancers
The resection of brain tumors can be critical concerning localization, but is a key point in treating gliomas. Intraoperative neuromonitoring (IONM), awake craniotomy, and mapping procedures have been incorporated over the years. Using these intraoperative techniques, the resection of eloquent-area tumors without increasing postoperative morbidity ...