Wilkinson, Dominic Jc Bertaud, Sophie
Published in
Seminars in fetal & neonatal medicine
While the underlying principles are the same, there are differences in practice in end of life decisions and care for extremely preterm infants compared with other newborns and older children. In this paper, we review end of life care for extremely preterm infants in the delivery room and in the neonatal intensive care unit. We identify potential j...
Boss, Renee D
Published in
Seminars in fetal & neonatal medicine
The sickest of NICU survivors develop chronic critical illness (CCI). Most infants with CCI will leave the NICU using chronic medical technology and will experience repeated rehospitalizations. The unique issues for these NICU graduates- escalating chronic medical technologies, fractured post-NICU healthcare, gaps in home health services, and famil...
Brum, Andrea C Vain, Nestor E
Published in
Seminars in fetal & neonatal medicine
After three years of the COVID-19 pandemic, we have learned many aspects of the disease and the virus: its molecular structure, how it infects human cells, the clinical picture at different ages, potential therapies, and the effectiveness of prophylaxis. Research is currently focused on the short- and long-term consequences of COVID-19. We review t...
Wild, K Taylor Burgos, Carmen Mesas Rintoul, Natalie E
Published in
Seminars in fetal & neonatal medicine
Extracorporeal membrane oxygenation (ECMO) is a universally accepted and life-saving therapy for neonates with respiratory or cardiac failure that is refractory to maximal medical management. Early studies found unacceptable risks of mortality and morbidities such as intracranial hemorrhage among premature and low birthweight neonates, leading to w...
Jensen, Amanda R Davis, Carl Gray, Brian W
Published in
Seminars in fetal & neonatal medicine
In neonates with cardiac and/or respiratory failure, extracorporeal membrane oxygenation (ECMO) continues to be an important method of respiratory and/or cardiovascular support where conventional treatments are failing. ECMO cannulation involves a complex decision-making process to choose the proper ECMO modality and cannulation strategy to match e...
Spencer, Brianna L Mychaliska, George B
Published in
Seminars in fetal & neonatal medicine
Despite significant advances in the treatment of prematurity, premature birth results in significant mortality and morbidity. In particular, extremely low gestational age newborns (ELGANs) defined as
Maul, Timothy M Herrera, Guillermo
Published in
Seminars in fetal & neonatal medicine
Neonatal extracorporeal life support (ECLS) has enjoyed a long history of successful patient support for both cardiac and respiratory failure. The small size of this patient population has provided many technical challenges from cannulation to pumps and oxygenators. This is further complicated by the relatively meager commercial options for equipme...
Kwok, T'ng Chang Henry, Caroline Saffaran, Sina Meeus, Marisse Bates, Declan Van Laere, David Boylan, Geraldine Boardman, James P Sharkey, Don
Published in
Seminars in fetal & neonatal medicine
Neonatal care is becoming increasingly complex with large amounts of rich, routinely recorded physiological, diagnostic and outcome data. Artificial intelligence (AI) has the potential to harness this vast quantity and range of information and become a powerful tool to support clinical decision making, personalised care, precise prognostics, and en...
Cramer, Sophie J E Kuypers, Kristel L A M Martherus, Tessa Dekker, Janneke Te Pas, Arjan B
Published in
Seminars in fetal & neonatal medicine
Very preterm infants are a unique and highly vulnerable group of patients that have a narrow physiological margin within which interventions are safe and effective. The increased understanding of the foetal to neonatal transition marks the intricacy of the rapid and major physiological changes that take place, making delivery room stabilisation and...
Ruoss, J L Moronta, S Cavallaro Bazacliu, C Giesinger, R E McNamara, P J
Published in
Seminars in fetal & neonatal medicine
Pulmonary hypertension in the neonate is associated with cardiopulmonary disturbances and neurodevelopment morbidity. The patent ductus arteriosus is a persistent fetal shunt that can be pathologic vs supportive in the setting of neonatal pulmonary hypertension. Understanding the underlying pathophysiology of pulmonary hypertension and the cardiopu...
