Prouteau, Anaïs Denis, Jérôme Alexandre De Fornel, Pauline Cadieu, Edouard Derrien, Thomas Kergal, Camille Botherel, Nadine Ulvé, Ronan Rault, Mélanie Bouzidi, Amira
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Published in
Scientific Reports
Circulating tumor DNA (ctDNA) has become an attractive biomarker in human oncology, and its use may be informative in canine cancer. Thus, we used droplet digital PCR or PCR for antigen receptor rearrangement, to explore tumor-specific point mutations, copy number alterations, and chromosomal rearrangements in the plasma of cancer-affected dogs. We...
Bélondrade, Maxime Nicot, Simon Mayran, Charly Bruyere-Ostells, Lilian Almela, Florian Di Bari, Michele A. Levavasseur, Etienne Watts, Joel C. Fournier-Wirth, Chantal Lehmann, Sylvain
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Published in
Scientific Reports
Unlike variant Creutzfeldt–Jakob disease prions, sporadic Creutzfeldt–Jakob disease prions have been shown to be difficult to amplify in vitro by protein misfolding cyclic amplification (PMCA). We assessed PMCA of pathological prion protein (PrPTSE) from 14 human sCJD brain samples in 3 substrates: 2 from transgenic mice expressing human prion prot...
Aglieri, Virginia Cagna, Bastien Velly, Lionel Takerkart, Sylvain Belin, Pascal
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Scientific Reports
Speaker recognition is characterized by considerable inter-individual variability with poorly understood neural bases. This study was aimed at (1) clarifying the cerebral correlates of speaker recognition in humans, in particular the involvement of prefrontal areas, using multi voxel pattern analysis (MVPA) applied to fMRI data from a relatively la...
Vaittinada Ayar, Pradeebane Vrac, Mathieu Mailhot, Alain
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Scientific Reports
Climate simulations often need to be adjusted (i.e., corrected) before any climate change impacts studies. However usual bias correction approaches do not differentiate the bias from the different uncertainties of the climate simulations: scenario uncertainty, model uncertainty and internal variability. In particular, in the case of a multi-run ens...
Malaisé, Yann Lencina, Corinne Cartier, Christel Olier, Maïwenn Ménard, Sandrine Guzylack-Piriou, Laurence
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Scientific Reports
Bisphenol (BP)A is an endocrine disruptor (ED) widely used in thermal papers. Regulatory restrictions have been established to prevent risks for human health, leading to BPA substitution by structural analogues, like BPS and BPF. We previously demonstrated that oral perinatal exposure to BPA had long-term consequences on immune responses later in l...
Filipiak, Michał Woyciechowski, Michal Czarnoleski, Marcin
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Scientific Reports
Life histories of species may be shaped by nutritional limitations posed on populations. Yet, populations contain individuals that differ according to sex and life stage, each of which having different nutritional demands and experiencing specific limitations. We studied patterns of resource assimilation, allocation and excretion during the growth ...
Surov, Ilya A. Semenenko, E. Platonov, A. V. Bessmertny, I. A. Galofaro, F. Toffano, Z. Khrennikov, A. Yu. Alodjants, A. P.
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Scientific Reports
The paper presents quantum model of subjective text perception based on binary cognitive distinctions corresponding to words of natural language. The result of perception is quantum cognitive state represented by vector in the qubit Hilbert space. Complex-valued structure of the quantum state space extends the standard vector-based approach to sema...
Ereira, Sam Pujol, Marine Guitart-Masip, Marc Dolan, Raymond J. Kurth-Nelson, Zeb
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Scientific Reports
Action is invigorated in the presence of reward-predicting stimuli and inhibited in the presence of punishment-predicting stimuli. Although valuable as a heuristic, this Pavlovian bias can also lead to maladaptive behaviour and is implicated in addiction. Here we explore whether Pavlovian bias can be overcome through training. Across five experimen...
Abbasi, Bilal Haider Khan, Taimoor Khurshid, Razia Nadeem, Muhammad Drouet, Samantha Hano, Christophe
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Scientific Reports
Fagonia indica (L.) is an important medicinal plant with multitude of therapeutic potentials. Such application has been attributed to the presence of various pharmacological important phytochemicals. However, the inadequate biosynthesis of such metabolites in intact plants has hampered scalable production. Thus, herein, we have established an in vi...
Sepúlveda, Edgardo Cordero, Raul R. Damiani, Alessandro Feron, Sarah Pizarro, Jaime Zamorano, Felix Kivi, Rigel Sánchez, Ricardo Yela, Margarita Jumelet, Julien
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Scientific Reports
Predicting radiative forcing due to Antarctic stratospheric ozone recovery requires detecting changes in the ozone vertical distribution. In this endeavor, the Limb Profiler of the Ozone Mapping and Profiler Suite (OMPS-LP), aboard the Suomi NPP satellite, has played a key role providing ozone profiles over Antarctica since 2011. Here, we compare o...