Nĕmecková, J Nĕmecek, S Náhlovský, J Parízek, J Sercl, M
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Sborník vědeckých prací Lékařské fakulty Karlovy university v Hradci Králové
In 1991-1993, 52 patients underwent surgery for low-grade supratentorial glioma. In 37 of them (astrocytoma 22, oligodentrocytoma 12, oligodendroglioma 2) seizures, often refractory to drug therapy, appeared as the first symptom. These cases were retrospectively analyzed. The patients had partial seizures: simple, complex, or secondarily generalize...
Herink, J
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Sborník vědeckých prací Lékařské fakulty Karlovy university v Hradci Králové
Convulsive activity of N-(3,5-dimethoxy-4-propoxy-phenyl-ethyl)-aziridine (FAZ-4), a newly synthetized aziridine compound was studied in rats. There is a lack of tonic component of major paroxysm in comparison with the classical convulsive agent pentylenetetrazol. This effect of FAZ-4 is probably due to the forebrain mechanism without the midbrain ...
Mokrý, J Nĕmecek, S
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Sborník vědeckých prací Lékařské fakulty Karlovy university v Hradci Králové
The trophoblast may serve as an example of tissue that is endowed with invasive properties under physiological conditions. Invasiveness of the trophoblast is enabled by the secretion of various proteases capable of degrading extracellular matrix components. Trophoblast invasive behavior is strictly controlled by anti-invasive factors produced by ut...
Taus, V
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Sborník vědeckých prací Lékařské fakulty Karlovy university v Hradci Králové
Unique character of brain tumors and problems inherent in different concepts of histological classification are impediments to effective histoprognosis. Large place for subjectivity may be diminished by integration of kinetics data into evaluation of tumor samples. Methods of measuring cell proliferation include immunohistochemical detection of hal...
Simek, J Resl, M
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Sborník vědeckých prací Lékařské fakulty Karlovy university v Hradci Králové
This report describes an unusual case of 35 year old man with endotracheal mesenchymoma. He was treated for two years as asthmoid bronchitis or asthma without any favourable result. The diagnosis was established by x-ray tomography and the patient was referred to the surgical treatment. The tumour was removed and the trachea was reconstructed. Post...
Kubová, Z Kuba, M
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Sborník vědeckých prací Lékařské fakulty Karlovy university v Hradci Králové
In addition to standard pattern-reversal VEPs, the motion-onset VEPs were examined in 50 patients with acute unilateral retrobulbar neuritis (RN) and in 187 patients with possible or definite multiple sclerosis (MS). In MS patients (without sign or history of RN), the results of both types of VEPs correlated only partially. 26.2% of them displayed ...
Slezák, R Krejsek, J Kopecký, O Drízhal, I
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Sborník vědeckých prací Lékařské fakulty Karlovy university v Hradci Králové
The total white blood cell count, percentage and total count of lymphocytes, CD3+, CD4+, and CD8+ subpopulations of T-lymphocytes, population of CD20+ B-lymphocytes, the ability of polymorphonuclears to phagocyte yeasts, the ability of polymorphonuclear cells to kill serum-resistant strain of E. coli and O2-dependent killing capacity of polymorphon...
Slízová, D Krs, O Bajgar, J Pospísilová, B
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Sborník vědeckých prací Lékařské fakulty Karlovy university v Hradci Králové
Vascularization of some organs of rat following soman (O-pinacolyl methylphosphonofluoridate) intoxication was studied using scanning electron microscopy. Corrosion casts were prepared with commercially available methyl metacrylate monomer which was partly polymerized, supplemented with catalyst and accelerator and injected into the prewashed and f...
Hobza, V Jakubec, J Nĕmecková, J Nĕmecek, S Sercl, M
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Sborník vědeckých prací Lékařské fakulty Karlovy university v Hradci Králové
Measurement of tissue impedance is a simple objective method for the localization of intracranial structures. Continuous bipolar impedance monitoring was performed during various CT-guided stereotactic procedures in 36 patients with brain pathology. The obtained values of the impedance profile along the trajectory were compared with the tissue dens...
Gersl, V Bajgar, J Krs, O Hrdina, R Vávrová, J Palicka, V Voglová, J Cerman, J Suba, P
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Sborník vědeckých prací Lékařské fakulty Karlovy university v Hradci Králové
The effects of the repeated i.v. administration of daunorubicin (50 mg/m2, once weekly, max. 9 weeks) were investigated in rabbits in vivo to analyze biochemical and hematological changes. Noninvasive polygraphic records were used to evaluate the function of the heart. The administration of daunorubicin induced changes especially in levels of prote...
