Published in Russian Journal of Physical Chemistry B
The antibacterial drug levofloxacin (LF) is micronized by the Rapid Expansion of the Supercritical Solution (RESS) method to obtain microparticles with a high level of bioavailability. Ethanol is used as a cosolvent to increase the solubility of LF in supercritical carbon dioxide. Spherical LF microparticles with the characteristic size of
Published in Russian Journal of Physical Chemistry B
This work presents the results of scaling up an analytical technique for supercritical chiral separation of salbutamol to a preparative scale. Chromatographic conditions are determined, and a technique for the preparative separation of the enantiomers by supercritical fluid chromatography is developed, in which the concentration of the R-isomer of ...
Published in Russian Journal of Physical Chemistry B
Supercritical fluid extraction of usnic acid (UA) from the lichen species Usnea subfloridana is optimized using a rotatable second-order composite design with uniform precision. The effect that the pressure, temperature, and the process duration have on the extract yield is evaluated. The following optimal values for the extraction parameters are e...
Published in Russian Journal of Physical Chemistry B
This review presents the results of a detailed analysis of the role of isochoric heat capacity as a key thermodynamic property of matter in the investigation of critical and supercritical phenomena. A brief historical background is given on the role and contribution of Russian scientific schools to the experimental investigation of the isochoric he...
Published in Russian Journal of Physical Chemistry B
The review considers the advances in the field of impregnation of polymers in supercritical media over the recent years. In particular, new approaches to the process of impregnation of polymers are described, and the possibility of application of new sub- and supercritical media for these purposes is demonstrated. Specific examples and conditions o...
Published in Russian Journal of Physical Chemistry B
AbstractThe effect of the density of water fluid in the range of ~10–3–0.25 g cm–3 on the structuring of amorphous silica gel was studied at 380°C that exceeds the temperature of critical point of water. It was shown that a decrease in the specific surface area (Ssp) is observed already at the lowest density. As the latter increases, Ssp decreases ...
Published in Russian Journal of Physical Chemistry B
The phase equilibrium of the propylene glycol–propane/butane system and the solubility of propylene glycol in a supercritical propane-butane mixture at temperatures of 403, 423, and 443 K are studied using a high-pressure optical cell. The results are described using the Peng–Robinson equation of state and the Mukhopadhyay and Rao mixing law.
Published in Russian Journal of Physical Chemistry B
A comparative study of n-butane conversion into aromatic hydrocarbons on a ZSM-5 zeolite in the H-form and modified with gallium or platinum at 530°C in the gas phase (at 1 atm) or under supercritical conditions (at 190 atm) is carried out. Under supercritical conditions, the catalysts demonstrate high levels of activity, stability, and productivit...
Published in Russian Journal of Physical Chemistry B
We compare the effects that different extraction methods based on green chemistry principles have on the degree of extraction of constituents of Scots pine (Pinus sylvestris) tree greenery. The gas chromatography–mass spectrometry analyses show that the alcohol extract, the essential oil, and the supercritical extract differ in their qualitative an...
Published in Russian Journal of Physical Chemistry B
The structure of 2 wt % aqueous solutions of ethanol, phenol, and o-methoxyphenol (guaiacol) was modeled in NVT ensemble using the classical molecular dynamics method at densities of 0.997 and 0.133 g/cm3 corresponding to the normal (298 K, 0.1 MPa) and supercritical (673 K, 23.0 MPa) conditions. The self-diffusion coefficients were calculated for ...
