Published in Russian Journal of Genetics
AbstractThere is a forecast that global demand for foods of animal and plant origin will increase by 74% by 2050 (Food and Agriculture Organization of the United Nations). Satisfying this demand without a destructive effect on the environment is only possible while maintaining the principles of organic farming, as well as introducing new technologi...
Published in Russian Journal of Genetics
AbstractThe results of comparative sequence analysis of pathogenicity islands (PIs), VPI-1 and VPI-2, in 43 nontoxigenic Vibrio cholerae strains are presented. It was demonstrated that these strains, differing from each other in the PI genome composition and structure, formed three genetically distinct groups (ctxA−tcpA+VPI-2+, ctxA−tcpA+VPI-2del+,...
Published in Russian Journal of Genetics
AbstractOxytocin represents one of the key element regulating social activity and aggressive behavior via its binding to oxytocin receptor (OXTR). Considering the multifactorial nature of developing aggression, the present study aimed to assess the main effects of the OXTR (rs53576, rs237911, rs7632287, rs2254298, rs2228485, rs13316193) gene polymo...
Published in Russian Journal of Genetics
AbstractThe review provides information on the function of the FTO gene (known as the fat mass and obesity-associated gene) and the encoded enzyme, on the functional role of single nucleotide polymorphisms (SNPs) in coding and noncoding gene regions and the range of their competences, and on association of the FTO polymorphisms with diseases and tr...
Published in Russian Journal of Genetics
AbstractThe role of the DnaKJE and Trigger Factor (TF) chaperones in folding and refolding of proteins in Bacillus subtilis is studied. Bacterial luciferases of Photobacterium leiognathi and Photorhabdus luminescens as protein substrates have been used. It is shown that DnaKJE takes part in folding but not in refolding of the thermal inactivated pr...
Published in Russian Journal of Genetics
AbstractUntil not so long ago, the main area of genetic studies of aggressive behavior was represented by associative analysis of candidate genes, which were identified according to the relationship of phenotypic manifestations of aggression with the functioning of neuromediator and reproductive systems. Recent years have been marked by development...
Published in Russian Journal of Genetics
AbstractThe present study was aimed to study HLA-DRB1, -DQB1 alleles and haplotypes of two endogamous groups of South India. PCR-SSP typing of HLA-DRB1, -DQB1 alleles were performed on 63 Mukkuvar, primarily a coastal population and 101 Valayar, a population primarily living on the fringes of forest areas. Genetic distances, neighbor-joining dendro...
Published in Russian Journal of Genetics
AbstractNonrandom distribution of meiotic recombination events along the chromosomes shapes the diversity of potential genetic combinations among the offspring. To redistribute the chromosomal regions involved in recombination events, it was proposed to use meiosis-specific genes of Spo11 proteins (generating double-strand DNA breaks) from phylogen...
Published in Russian Journal of Genetics
AbstractOn practical material (samples of wild boar and seven main breeds of domestic pig in Belarus), we confirmed the high differentiating potential of H3GA0051814 polymorphism (HEPH gene). To differentiate between wild boar and domestic pig, we proposed a test model of three SNPs—H3GA0051814 (HEPH), c.367G>A (MC1R), and g.299084751C>T (NR6A1). T...
Published in Russian Journal of Genetics
AbstractGenetic diversity of a large number of populations is analyzed using various Y-chromosome markers. Genotyping of a wide range of novel highly informative SNP and YSTR markers shows that most of the Y-chromosome haplogroups can be divided not only into ethnically specific lineages but also into narrower sublineages and clusters of haplotypes...
