Shur, K. V. Frolova, S. G. Akimova, N. I. Danilenko, V. N. Maslov, D. A.
Published in
Russian Journal of Genetics
AbstractEmergence of drug-resistance to antituberculosis agents is a global challenge that requires development of novel drugs, active against resistant Mycobacterium tuberculosis strains. One of the tasks of drug development is to determine the mechanism of resistance of the pathogen to the drug candidate. The mycobacterial MmpS5-MmpL5 efflux syst...
Semerikova, S. A. Isakov, I. Yu. Semerikov, V. L.
Published in
Russian Journal of Genetics
AbstractChloroplast DNA variation was investigated in 42 populations of pedunculate oak, Quercus robur L., in the European part of Russia, Belarus, Poland, Ukraine, the Urals, and the Caucasus. Restriction analysis and sequencing, as well as chloroplast DNA microsatellite loci (cpSSR), were used as genetic markers. For successful amplification and ...
Kartavtseva, I. V. Sheremetyeva, I. N. Pavlenko, M. V.
Published in
Russian Journal of Genetics
AbstractOn the basis of a study of our own and published data on voles from the shores of Lake Evoron (n = 8) and the Amgun River (n = 8) in the Evoron-Chukchagir lowland, as well as individuals from laboratory breeding, new data on karyotypic variation (2n = 38–41, NF = 54–59), chromosomal transformations, and their combinations in the karyotype a...
Gan, W. Zhang, N. N. Li, L.
Published in
Russian Journal of Genetics
AbstractThe aim of this study was to investigate the effect of AMPK/FOXO3 signal pathway on duck myoblasts apoptosis and differentiation the possible mechanisms. Dorsomorphin 2HCl (DOR) and AICAR were used to inhibited and activated AMPK expression, respectively. And then, the myoblasts apoptosis and differentiation were established by dexamethason...
El’chinova, G. I. Zinchenko, R. A.
Published in
Russian Journal of Genetics
AbstractThe study was performed using archival data from the laboratory of genetic epidemiology of the Research Center for Medical Genetics. Of the 65 747 marriage records for Udmurtia, Chuvashia, Mari El, Bashkiria, and Tatarstan dating back to the end of the 20th century, 15 804 were selected in which at least one of the spouses was Russian. Russ...
Parfenchyk, M. S. Kotava, S. A.
Published in
Russian Journal of Genetics
AbstractThe knowledge of the ancestry of an unknown individual from forensic DNA may provide important information for law enforcement investigation. This information can be acquired from biological traces by means of massive parallel sequencing (MPS) technologies and developed arrays of ancestry informative DNA markers (AIM panels). Development of...
Dyachenko, E. A. Kulakova, A. V. Meleshin, A. A. Shchennikova, A. V. Kochieva, E. Z.
Published in
Russian Journal of Genetics
AbstractStarch degradation in plants is mediated by amylases, the activity of which is post-translationally regulated by inhibitors. It is assumed that the SbAI amylase inhibitor activity is associated with potato cold stress resistance. The study of possible correlations of the SbAI variability with the cold resistance of potato species will impro...
Serebrova, V. N. Trifonova, E. A. Stepanov, V. A.
Published in
Russian Journal of Genetics
AbstractThe review discusses the data on the significant role of pregnancy in adaptive evolution of modern humans. In the aspect of evolutionary medicine, the main attention is paid to preeclampsia (PE), a severe hypertensive pathology of pregnancy. The current evolutionary hypotheses about the origin and causes of racial and ethnic variability in ...
Artyushin, I. V. Konorov, E. A. Kurbakov, K. A. Stolpovsky, Y. A.
Published in
Russian Journal of Genetics
AbstractIn our study, we developed a primer system and optimized the PCR protocol for amplification of the reindeer (Rangifer tarandus) mitochondrial genome. We sequenced and assembled two mitochondrial genomes of wild and domestic reindeer from the Nenets Autonomous Okrug. These two genomes were compared with known sequenced mitochondria of domest...
Efetov, K. A. Lazareva, Z. S. Parshkova, E. V. Tarmann, G. M.
Published in
Russian Journal of Genetics
AbstractThe paper presents qualitative and quantitative composition of the nucleotide sequences of the 5'‑region of the first subunit of the mitochondrial cytochrome oxidase (COI) gene (decoded in the framework of the International DNA Barcoding Project) and the variability of the corresponding amino acid sequences in the genus Jordanita Verity, 19...
