Orlova, E. A. Ogarkov, O. B. Khromova, P. A. Sinkov, V. V. Khasnatinov, M. A. Zhdanova, S. N. Rychkova, L. V. Kolesnikova, L. I.
Published in
Russian Journal of Genetics
Cross-replicating associations with rs657152 at the 9q34.2c locus and rs11385942 at the 3p21.31 locus found in patients with severe COVID-19 in the Caucasian population require the study of the discovered phenomenon in various populations, including as an independent biological marker. Primers and TaqMan probes for PCR discrimination of the A and C...
Glotov, O. S. Chernov, A. N. Scherbak, S. G. Baranov, V. S.
Published in
Russian Journal of Genetics
The COVID-19 coronavirus pandemic has spread to 215 countries around the world and caused tens of millions of infections and more than a million deaths worldwide. In the midst of COVID-19 infection, it is extremely important to identify new protein and gene targets that may be highly sensitive diagnostic and prognostic markers of the severity and o...
Bochkarev, N. A. Sendek, D. S. Zuykova, E. I. Pestryakova, L. P. Zakhrov, E. S. Zakharova, N. N. Koryakina, L. P. Politov, D. V.
Published in
Russian Journal of Genetics
AbstractThe results of morphogenetic analysis of sympatric forms/species of the Coregonus lavaretus pidschian (Coregonus pidschian) complex from the Olenek River basin are presented. It was demonstrated that the Olenek River basin was inhabited by three distant forms of whitefishes. Two of these forms, C. lavaretus pidschian n. brachymystax and C. ...
Axenovich, T. I. Belonogova, N. M. Zorkoltseva, I. V. Tsepilov, Ya. A.
Published in
Russian Journal of Genetics
AbstractNeuroticism is a personality trait, which is an important risk factor for psychiatric disorders. Recent genome-wide studies have reported about 600 genes potentially influencing neuroticism. This list consists of both genes whose polymorphisms directly regulate the level of neuroticism and genes whose expression is controlled by genetic var...
Brandler, O. V. Tukhbatullin, A. R. Kapustina, S. Yu. Schepetov, D. M. Titov, S. V. Ermakov, O. A.
Published in
Russian Journal of Genetics
AbstractRusset ground squirrel (Spermophilus major) is a widespread species with an extended range, partly separated by the Ural Ridge into eastern and western parts. Previously, a hybridization of the russet ground squirrel in contact areas with five other Spermophilus species, accompanied by a wide introgression of their mitochondrial genomes, wa...
Stepanova, A. A. Ivanova, E. A. Kadyshev, V. V. Polyakov, A. V.
Published in
Russian Journal of Genetics
AbstractX-linked juvenile retinoschisis is a hereditary eye disease that belongs to the group of retinal dystrophy. This study presents the results of the search for mutations in the RS1 gene in 48 unrelated men diagnosed with X-linked juvenile retinoschisis. Molecular genetic diagnosis was found in 77% of the probands. Revealed were 27 different p...
Kotova, V. Yu. Abilev, S. K. Zavilgelsky, G. B.
Published in
Russian Journal of Genetics
AbstractThe K-ratio between diadducts (D) and monoadducts (M) induced by 8-methoxypsoralen (8-MOP) in the DNA packed in the head of bacteriophage λ and in the DNA of pBR322 plasmid under UV irradiation (λ ≥ 320 nm) was measured. The probabilities of UVR excision repair of 8-MOP monoadducts (P) and of SOS repair of 8-MOP diadducts and monoadducts (S...
Savchenko, R. R. Murashkina, A. A. Fishman, V. S. Sukhikh, E. S. Vertinsky, A. V. Sukhikh, L. G. Serov, O. L. Lebedev, I. N. Vasilyev, S. A.
Published in
Russian Journal of Genetics
AbstractThe effect of knockout and overexpression of the ADAMTS1 on the radiation-induced response in HeLa cell line was analyzed. The cell line with the ADAMTS1 gene knockout was created using the CRISPR/Cas9 genome editing technology. The ADAMTS1 gene overexpression was ensured by transient transfection of the plasmid containing the gene of inter...
Vorobyeva, N. E. Mazina, M. Yu.
Published in
Russian Journal of Genetics
AbstractUntil recently, the main transcription coregulator proteins were considered to be complexes that altered the chromatin structure, namely, the chromatin remodelers and histone modifiers. However, the latest studies of the mechanisms of transcriptional regulation made it possible to refine this classification. Two additional classes of transc...
Fan, X. Y. Qiu, L. H. Zhang, Y. Y. Teng, X. H. Miao, Y. W.
Published in
Russian Journal of Genetics
AbstractAlpha-lactalbumin (α-LA) is a unique whey protein associated with lactation traits in ruminants, but so far, buffalo LALBA gene have not been well understood. In this work, the polymorphisms of LALBA gene in river type and swamp type buffalo were identified using direct sequencing of PCR product. As a result, 26 single nucleotide polymorphi...
