Syrbu, S. A. Kiselev, A. N. Lebedev, M. A. Gubarev, Yu. A. Yurina, E. S. Lebedeva, N. Sh.
Published in
Russian Journal of General Chemistry
AbstractNovel porphyrin compounds containing benzothiazole, benzoxazole, and benzimidazole moieties have been prepared and their structures have been confirmed. Molecular docking of non-symmetric hetaryl-substituted porphyrins and chlorin e6 with SARS-CoV-2 helicase has been carried out. The affinity of hetaryl-substituted porphyrins to this protei...
El-Sayed, H. A. Said, S. A. El-Hamid, A. Abd Mohamed, A. S. A. Amr, A. E. Morsy, H. A.
Published in
Russian Journal of General Chemistry
AbstractHerein, synthesis of a new series of pyrano[2,3-d]pyrimidine scaffolds is presented. Ethyl 6-amino-4-(4-chlorophenyl)-5-cyano-2-methyl-4H-pyran-3-carboxylate has been reacted with formamide, formic acid, urea, thiourea, semicarbazide, and thiosemicarbazide to give six new pyrano[2,3-d]pyrimidine derivatives in moderate to high yields (48–78...
Sadykova, Yu. M. Zalaltdinova, A. V. Smailov, А. K. Burilov, А. R. Pudovik, М. А.
Published in
Russian Journal of General Chemistry
AbstractAn original, new method for the synthesis of previously unknown diaryl(hetaryl)ethylphosphonic acids containing pharmacophoric fragments was developed as a result of the acid-catalyzed reaction of (2-ethoxyvinyl)phosphonic dichloride with heterocyclic compounds such as 4-hydroxy-6-methyl-2-pyrone, 4-hydroxycoumarin, and also thymol and carv...
Romanov, S. R. Bakhtiyarova, Yu. V. Morozov, M. V. Karataeva, F. Kh. Klochkov, V. V. Galkina, I. V. Galkin, V. I.
Published in
Russian Journal of General Chemistry
AbstractThe nucleophilic addition reactions of tertiary phosphines and unsaturated carboxylic acids have led to the formation of mono- and dicarboxylate phosphabetaines containing an asymmetric carbon atom. The data of 1D and 2D NMR spectroscopy have revealed the presence of diastereotopic geminal protons of the CH2 group adjacent to the chiral cen...
Chernov, N. M. Lebedev, M. Yu. Luk’yanenko, V. I. Shutov, R. V. Yakovlev, I. P.
Published in
Russian Journal of General Chemistry
AbstractA procedure has been developed for the synthesis of 6,7-dihydroindazoles and 7,8-dihydroquinazolines by reaction of 3,4-dihydroxanthone derivatives with 1,2- and 1,3-binucleophiles (hydrazine, guanidine). The reaction occurred under mild conditions (methanol, 20-65°C) with high yields.
Egorova, I. V. Zhidkov, V. V. Grinishak, I. P. Rodionova, N. А. Bagryanskaya, I. Yu. Pervukhina, N. V.
Published in
Russian Journal of General Chemistry
AbstractIt was first found that the alkylation of tris(4-N,N-dimethylaminophenyl)stibine with methyliodide leads to the formation of tris(4-N,N-dimethylaminophenyl)methylstibonium iodide which decomposes in hot water to tris(4-N,N-dimethylaminophenyl)stibine. The reaction of [(4-N,N-Me2C6H4)3MeSb]I with HgI2 in DMSO yields [(4-N,N-(Me)2C6H4)3MeSb]2...
Li, Y. P. Li, G. L. Xin, L. Y. Li, X. L. Liu, G. Z.
Published in
Russian Journal of General Chemistry
AbstractTwo new coordination polymers, {[Mn2(L)(H2O)2]·H2O}n (1) and {[Co2(L)(H2O)2]·H2O}n (2) (H4L = 2-(2,4,6-tricarboxylphenyl)-6-carbxoylbenzimi-dazole), have been synthesized under hydrothermal conditions and characterized by element analysis, powder XRD and single crystal X-ray diffraction. The results indicate complex 1 as a 2D carboxylate la...
Gein, V. L. Pastukhova, E. V.
Published in
Russian Journal of General Chemistry
AbstractThe reaction of methyl aroylpyruvate with a mixture of aromatic aldehyde and glycocol in a dioxane–water mixture (1 : 1) leads to the formation of a new series of 5-aryl-4-aroyl-3-hydroxy-1-carboxymethyl-3-pyrroline-2-ones. Structure of the obtained compounds was determined by IR and 1H NMR spectroscopy methods.
Viktorov, N. B. Gurzhiy, V. V. Dogadina, A. V.
Published in
Russian Journal of General Chemistry
AbstractThe reactions of (2-chloroethynyl)diphenylphosphine oxide with diethyl 2-aminomalonate and of dimethyl (2-chloroethynyl)phosphonate with 2-amino-N1,N3-di(p-tolyl)malonamide or 2-aminomalonamide proceed chemo- and regioselectively to yield the corresponding 2-(phosphorylmethylene)oxazoles, namely diphenyl-[(4-ethoxycarbonyl-5-ethoxyoxazol-2-...
Galenko, E. E. Kaminskiy, N. A. Novikov, M. S. Khlebnikov, A. F.
Published in
Russian Journal of General Chemistry
AbstractA method for the synthesis of water-soluble α-aminopyrroles, 1-(2-amino-1H-pyrrol-3-yl)pyridinium chlorides, by the reaction 1-(cyanomethyl)pyridinium chloride with alkyl 3-aryl-2H-azirine-2-carboxylates was developed.
