Hou, Xing Fang Hou, Cheng Gou
Published in
Respiratory medicine
Fractional exhaled nitric oxide (FeNO) is a marker of type 2 airway inflammation. Tobacco exposure can lower FeNO levels. However, the effect of acute tobacco exposure on FeNO in patients with chronic obstructive pulmonary disease (COPD) is unclear. This study aimed to investigate the relationship of acute tobacco exposure with FeNO and eosinophils...
Smith, Hannah Easterling, Robert Ma, Jianing Moodabagil, Meghana Meara, Alexa Owen, Dwight H Crouser, Elliot Singha, Arindam Ho, Kevin
Published in
Respiratory medicine
Sarcoid-like reactions (SLRs) to immune checkpoint inhibitors (ICIs) are a rare but increasingly recognized immune-related adverse event of which the clinical significance is unclear. We conducted a retrospective cohort study at a tertiary academic center of consecutive patients who received at least one dose of ICI from 2013 to 2020. Patient chara...
Ternesten-Hasséus, Ewa Johansson, Ewa-Lena Corresponding author...
Published in
Respiratory medicine
Cough is considered chronic when it lasts for >8 weeks. When no medical explanation can be found it is often called unexplained chronic cough (UCC), which may affect health-related quality of life (HRQOL). This study aimed to assesses the validity and reliability of the Swedish version of the Leicester Cough Questionnaire (LCQ-S) in patients with U...
Almqvist, Linnéa Andersson, Martin Backman, Helena Rönmark, Eva Hedman, Linnéa
Published in
Respiratory medicine
Although remission occur, childhood-onset asthma may persist until adulthood. Since few longitudinal population-based studies have followed a cohort from childhood until adulthood, the knowledge on predictors of persistence of asthma is sparse. To estimate persistence of asthma from 8 to 28 years and its associated factors. Within the OLIN (Obstruc...
Posthuma, Rein van der Molen, Marieke C Hartman, Jorine E Spruit, Martijn A Slebos, Dirk-Jan Vanfleteren, Lowie E G W Vaes, Anouk W
Published in
Respiratory medicine
Patients with advanced emphysema eligible for bronchoscopic lung volume reduction (BLVR) using endobronchial valves (EBV) are characterized by severe static lung hyperinflation, which can be considered a treatable trait. Other treatable traits (TTs), which are assumed to be present in this highly selected patient group, have not been studied in det...
Papi, Alberto Castro, Mario Corren, Jonathan Pavord, Ian D Tohda, Yuji Altincatal, Arman Pandit-Abid, Nami Laws, Elizabeth Akinlade, Bolanle Mannent, Leda P
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Published in
Respiratory medicine
TRAVERSE (NCT02134028), a phase 3 open-label extension study, assessed dupilumab safety and efficacy in patients with asthma aged ≥12 years who completed a previous dupilumab asthma study. This analysis evaluated changes in multiple lung function parameters in patients with moderate-to-severe asthma with elevated type 2 biomarkers (baseline eosinop...
Salguero, Bertin D Salman, Sidra Agrawal, Abhinav Lo Cascio, Christian M Joy, Greta Chaddha, Udit
Published in
Respiratory medicine
Medical Thoracoscopy (MT) is a diagnostic procedure during which after accessing the pleural space the patient's negative-pressure inspiratory efforts draw atmospheric air into the pleural cavity, which creates a space to work in. At the end of the procedure this air must be evacuated via a chest tube, which is typically removed in the post-anesthe...
Hajmohammadi, Hajar Talaei, Mohammad Fecht, Daniela Wang, Weiyi Vivaldi, Giulia Faustini, Sian E Richter, Alex G Shaheen, Seif O Martineau, Adrian R Sheikh, Aziz
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Published in
Respiratory medicine
The association between air quality and risk of SARS-CoV-2 infection is poorly understood. We investigated this association using serological individual-level data adjusting for a wide range of confounders, in a large population-based cohort (COVIDENCE UK). We assessed the associations between long-term (2015-19) nitrogen dioxide (NO2) and fine par...
De Bortoli, Alessandro Dawson, Kristin A Hashem, Dalia Spence, Stewart David Pena, Elena Inacio, João R Nery, Pablo Juneau, Daniel Dwivedi, Girish Beanlands, Robert
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Published in
Respiratory medicine
clinically silent cardiac sarcoidosis (CS) may be associated with adverse outcomes, hence the rationale for screening patients with extracardiac sarcoidosis. The optimal screening strategy has not been clearly defined. patients with extra-cardiac sarcoidosis were prospectively included and underwent screening consisting of symptom history, electroc...
Mondal, Pritish Lopez, Stephanie Padilla Khokhar, Arshjot Snyder, David Kitch, Diane Veten, Ahmed
Published in
Respiratory medicine
Impulse oscillometry (IOS) is an effective tool for assessing airway mechanics and diagnosing obstructive airway disease (OAD) in children with sickle cell disease (C-SCD). Obesity is known to be associated with OAD, and untreated OAD often leads to hypoxia-related complications in C-SCD. Considering the increasing prevalence of obesity in C-SCD, i...
