Dathe, Katarina Fietz, Anne-Katrin Pritchard, Lucas William Padberg, Stephanie Hultzsch, Stefanie Meixner, Katja Meister, Reinhard Schaefer, Christof
Published in
Reproductive toxicology (Elmsford, N.Y.)
Ibuprofen is an analgesic frequently used in the 1st and 2nd trimester of pregnancy. Most relevant studies deal with NSAID as a group and do not specifically focus on ibuprofen. In this study, 1117 women exposed to ibuprofen in the 1st trimester were compared to 2229 non-exposed women. Data were retrieved from the German Embryotox database. No sign...
Sampayo-Reyes, Adriana Taméz-Guerra, Reyes S Bermúdez de León, Mario Vargas-Villarreal, Javier Lozano-Garza, Héctor Gerardo Rodríguez-Padilla, Cristina Cortés, Constanza Marcos, Ricard Hernández, Alba
Published in
Reproductive toxicology (Elmsford, N.Y.)
Human studies suggest that in utero exposure to arsenic results in adverse pregnancy outcomes. The use of dietary supplements, such as sodium selenite (SS) or α-tocopherol succinate (α-TOS), is a reasonable approach to ameliorate such health effects. Sodium arsenite at 100ppm was administered via drinking water to female hamsters from gestational d...
Martinez-Pinto, J Piquer, B Tiszavari, M Lara, H E
Published in
Reproductive toxicology (Elmsford, N.Y.)
To understand the impact of exposure to steroids in the early step of ovary development (a stage occurring in uterus in humans), we studied neonatal exposure to estradiol valerate (EV) in rats regarding polycystic ovary (PCO) development as well as expression of androgen receptor (Ar) and anti-Müllerian hormone (AMH), a marker of ovarian follicular...
Liu, Han-Xiao Hou, Li-Fang Chen, Ting Qu, Wen Liu, Sha Yan, Hui-Yi Wen, Xiao Ping, Jie
Published in
Reproductive toxicology (Elmsford, N.Y.)
This study aimed to investigate the association between prenatal caffeine ingestion (PCI) and risk of postnatal pulmonary inflammation. Pregnant Wistar rats were administered 60mg/kg/d caffeine intragastrically from gestational day (GD) 7 to GD 20. The results showed that PCI obviously increased intrauterine growth retardation rate to 39.2% and sup...
Moreira, N Sandini, T M Reis-Silva, T M Navas-Suáresz, P Auada, A V V Lebrun, I Flório, J C Bernardi, M M Spinosa, H S
Published in
Reproductive toxicology (Elmsford, N.Y.)
Ivermectin (IVM) is a macrocyclic lactone used for the treatment of parasitic infections and widely used in veterinary medicine as endectocide. In mammals, evidence indicates that IVM interacts with γ-aminobutyric acid (GABA)-mediated chloride channels. GABAergic system is involved in the manifestation of sexual behavior. We previously found that I...
Shahin, Saba Singh, Surya Pal Chaturvedi, Chandra Mohini
Published in
Reproductive toxicology (Elmsford, N.Y.)
Present study investigated the long-term effects of mobile phone (1800MHz) radiation in stand-by, dialing and receiving modes on the female reproductive function (ovarian and uterine histo-architecture, and steroidogenesis) and stress responses (oxidative and nitrosative stress). We observed that mobile phone radiation induces significant elevation...
Friedman, S Larsen, M D Magnussen, B Jølving, L R de Silva, P Nørgård, B M
Published in
Reproductive toxicology (Elmsford, N.Y.)
There was no negative impact of paternal preconception use of AZA/6-MP/MTX on selected childhood health outcomes.
Loreto-Gómez, Carmen Farías, Paulina Moreno-Macías, Hortensia Romano-Riquer, S P Riojas-Rodríguez, Horacio
Published in
Reproductive toxicology (Elmsford, N.Y.)
There is no consensus on which anogenital distance (AGD) variant to use and how to adjust it by body size in humans. This study quantitatively evaluated AGD variants and body size adjustments to determine which would be the best choice. AGD variants, height, and weight were measured on five occasions during the first year of life of 307 infants. Th...
Ghazipura, Marya McGowan, Richard Arslan, Alan Hossain, Tanzib
Published in
Reproductive toxicology (Elmsford, N.Y.)
Hydroxy-4-methoxybenzophenone, also known as benzophenone-3 (BP-3), is a commonly used ultraviolet filter in skincare and as a food additive. Large concentrations of similar phenolic compounds have been detected in urine, amniotic fluid, and placental tissue, thereby raising questions about its impact on reproduction. The objective of this paper wa...
Lee, Hae-Miru Kim, Cho-Won Hwang, Kyung-A Sung, Jae-Hyuck Lee, Jin-Kyu Choi, Kyung-Chul
Published in
Reproductive toxicology (Elmsford, N.Y.)
Cigarette smoke (CS) is well known to be very harmful to human body functions such as fertility, reproduction, and development. CS is considered to more affect patients with hypertension (HT). To estimate the effect of CS associated with female rat's fertility, we examined the histopathological characteristics of the uterus and ovary which were obt...
