Ross, Malcolm Strachan Chandler, Chelsea Kilpatrick Matsuo, Koji Vargo, John Austin Elishaev, Esther Siripong, Nalyn Berger, Jessica Layne Kelley, Joseph Leo 3rd Taylor, Sarah Elizabeth
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Rare tumors
Uterine carcinosarcoma is a rare and aggressive tumor with poor outcomes. Cancer antigen 125 is routinely used to track the disease course of ovarian cancer and has been suggested as a biomarker in other aggressive forms of uterine cancer. We sought to characterize cancer antigen 125 as a potential biomarker of disease status in uterine carcinosarc...
Hansen, Carsten Palnaes Kristensen, Thomas Skaarup Storkholm, Jan Henrik Federspiel, Birgitte Hartnack
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Rare tumors
Solid pseudopapillary neoplasm of the pancreas is a rare tumor of low malignancy that occurs most often in females. The study describes the clinicopathologic characteristics of the tumor and common differential diagnoses. Data were collected from a prospectively maintained database. Of 1661 patients operated for pancreatic tumors between January 20...
Mohaidat, Ziyad M Al-Jamal, Hisham Z Bany-Khalaf, Audai M Radaideh, Ahmad M Audat, Ziad A
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Rare tumors
Giant cell tumor of bone is a benign tumor with an aggressive behavior. Its typical subarticular location and high recurrence risk can be associated with significant morbidity. Although benign, it can rarely metastasize especially to the lungs. Also, it can be multicentric in less than 1% of patients. Late malignant transformation, although rare, c...
Eto, Satoshi Kai, Kentaro Nasu, Kaei Nishida, Masakazu Nishida, Haruto Narahara, Hisashi
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Rare tumors
Small cell carcinoma of the uterine cervix is a rare histological entity that has a poor prognosis. We report the case of a patient with small cell carcinoma of the uterine cervix who underwent a radical hysterectomy during pregnancy. A 33-year-old Japanese woman with genital bleeding was referred at 15 weeks' gestation. A speculum exam revealed a ...
Borrelli, Eric Babcock, Zachary Kogut, Stephen
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Rare tumors
Malignant mesothelioma is a rare and devastating form of cancer with an increasing economic burden. We sought to describe the direct cost burden of mesothelioma to the US health system. A systematic literature review was performed to locate published estimates of the medical cost of mesothelioma. In addition, we performed an analysis of hospital di...
Wang, Haotong Miao, Ruoyu Jacobson, Alex Harmon, David Choy, Edwin Hornicek, Francis Raskin, Kevin Chebib, Ivan DeLaney, Thomas F Chen, Yen-Lin E
...
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Rare tumors
Purpose: This study is to present a large cohort of extraskeletal osteosarcoma (ESOS) and evaluate prognostic factors and treatment options. Methods: Medical records were reviewed retrospectively for 41 patients with extraskeletal osteosarcoma that was diagnosed by pathology, and treated at our institution between 1960 and 2016. Kaplan-Meier analys...
Peixoto, R D Gomes, L M Sousa, T T Racy, D J Shigenaga, M Nagourney, R A
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Rare tumors
Although rare, adrenocortical carcinoma is among the most common tumors found in children with Li-Fraumeni syndrome and Li-Fraumeni-like syndrome, associated with germ-line mutations in the TP53 gene. In southern Brazil, one form of Li-Fraumeni syndrome, associated with childhood adrenocortical carcinoma, is caused by a mutation in the R337H TP53 t...
Espejo, Andrea P Ramdial, Jeremy L Wilky, Breelyn A Kerr, Darcy A Trent, Jonathan C
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Rare tumors
In patients with sarcoma, concomitant malignancy is found in 1.2% -2.5% of cases. Previous studies have demonstrated conflicting results in terms of positive or negative effects on cancer prognosis with comorbid sarcoidosis. Additionally, there are no data determining whether an association between sarcoidosis and sarcomas exists. Finding an associ...
Blank, Alan Todd Khalighi, Mazdak Randall, R Lor Jones, Kevin B
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Rare tumors
Soft tissue sarcomas are a rare group of mesenchymal malignancies which can range from low to high grade. These tumors have different clinical, radiographic, and histopathological characteristics. Beta human chorionic gonadotropin is a naturally secreted hormone by placental syncytiotrophoblast cells during pregnancy. On very rare occasions, sarcom...
Wylleman, Robbert Debiec-Rychter, Maria Sciot, Raf
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Rare tumors
We report the exceptional occurrence of murine double minute clone 2 amplification in an atypical meningioma and its recurrent anaplastic meningioma arising in the right frontal lobe of a 75-year-old man. Murine double minute clone 2 amplification was shown by array comparative genomic hybridization and confirmed by fluorescence in situ hybridizati...