Rowe, Lindsay S. Harmon, Stephanie Horn, Adam Shankavaram, Uma Roy, Soumyajit Ning, Holly Lindenberg, Liza Mena, Esther Citrin, Deborah E. Choyke, Peter
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Published in
Radiation Oncology
BackgroundProstate Membrane Specific Antigen (PSMA) positron emission tomography (PET) and multiparametric MRI (mpMRI) have shown high accuracy in identifying recurrent lesions after definitive treatment in prostate cancer (PCa). In this study, we aimed to outline patterns of failure in a group of post-prostatectomy patients who received adjuvant o...
Mehrnia, Somayeh Sadat Hashemi, Bijan Mowla, Seyed Javad Nikkhah, Maryam Arbabi, Azim
Published in
Radiation Oncology
BackgroundGold nanoparticles (GNPs) have been used to sensitize cancer cells and enhance the absorbed dose delivered to such cells. Active targeting can provide specific effect and higher uptake of the GNPs in the tumor cells, while having small effect on healthy cells. The aim of this study was to assess the possible radiosensitiazation effect of ...
Jiang, Cecilia Kleber, Troy J. Switchenko, Jeffrey M. Khan, Mohammad K.
Published in
Radiation Oncology
BackgroundThe management of melanoma with brain metastases (MBM) is increasingly complex, especially given recent improvements in targeted agents, immunotherapy, and radiotherapy. Whole brain radiation therapy (WBRT) is a longstanding radiotherapy technique for which reported patient outcomes and experiences are limited. We sought to report our ins...
Stevens, Mark J. West, Simon Gard, Gregory Renaud, Christopher Nevell, David Roderick, Stephanie Le, Andrew
Published in
Radiation Oncology
BackgroundTo evaluate the initial experience and clinical utility of first-line adjuvant intensity-modulated whole abdominal radiation therapy (WART) in women with ovarian clear cell cancer (OCCC) referred to an academic center.MethodsProgression-free and overall survival was analyzed in a pragmatic observational cohort study of histologically pure...
Athanasiadi, Ilektra Perez, Whitney D. Plantenga, Jeannie M. Jones-Hall, Yava Perez-Torres, Carlos J.
Published in
Radiation Oncology
BackgroundRadiation-induced brain injury is a common concern for survivors of adult and pediatric brain cancer. Pre-clinically, rodent models are the standard approach to evaluate mechanisms of injury and test new therapeutics for this condition. However, these rodent models fail to recapitulate the radiological and histological characteristics of ...
Vogin, Guillaume Hettal, Liza Bartau, Clarisse Thariat, Juliette Claeys, Marie-Virginie Peyraga, Guillaume Retif, Paul Schick, Ulrike Antoni, Delphine Bodgal, Zsuzsa
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Published in
Radiation Oncology
BackgroundSegmentation is a crucial step in treatment planning that directly impacts dose distribution and optimization. The aim of this study was to evaluate the inter-individual variability of common cranial organs at risk (OAR) delineation in neurooncology practice.MethodsAnonymized simulation contrast-enhanced CT and MR scans of one patient wit...
Corradini, Stefanie Niyazi, Maximilian Verellen, Dirk Valentini, Vincenzo Walsh, Seán Grosu, Anca-L. Lauber, Kirsten Giaccia, Amato Unger, Kristian Debus, Jürgen
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Published in
Radiation Oncology
Future radiation oncology encompasses a broad spectrum of topics ranging from modern clinical trial design to treatment and imaging technology and biology. In more detail, the application of hybrid MRI devices in modern image-guided radiotherapy; the emerging field of radiomics; the role of molecular imaging using positron emission tomography and i...
Kunogi, Hiroaki Yamaguchi, Nanae Terao, Yasuhisa Sasai, Keisuke
Published in
Radiation Oncology
PurposeWe sought dosimetric predictors of a decreasing estimated glomerular filtration rate (eGFR) in gynecological oncology patients receiving extended-field radiation therapy (EFRT).Materials and methodsBetween July 2012 and April 2020, 98 consecutive cervical or endometrial cancer patients underwent EFRT or whole-pelvis radiation therapy (WPRT) ...
Prabhu, Roshan S. Dhakal, Reshika Hicks, Amy S. McBride, James Patrick, Alicia L. Corso, Christopher D. Murphy, Tomain Thonen, Melissa Lipford, Edward H. Raghavan, Derek
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Published in
Radiation Oncology
BackgroundCoronavirus disease 2019 (COVID-19) caused by the SARS-CoV-2 virus is a current pandemic. We initiated a program of systematic SARS-CoV-2 polymerase chain reaction (PCR) testing in all asymptomatic patients receiving radiotherapy (RT) at a large radiation oncology network in the Charlotte, NC metropolitan region and report adherence and r...
Xiang, Xiaoyong Ding, Zhen Feng, Lingling Li, Ning
Published in
Radiation Oncology
ObjectiveThis meta-analysis evaluated the efficacy and safety of accelerated partial breast irradiation versus whole-breast irradiation for early-stage breast cancer after breast-conserving surgery.Materials and methodsA systematic search of PubMed, Embase, and the Cochrane libraries was performed according to the PRISMA statement the last 10 years...
