Ren, Bixin Guo, Qi Yang, Yongqiang Liu, Lei Wei, Shaohua Chen, Wei Tian, Ye
Published in
Radiation Oncology
ObjectiveThe benefit of adjuvant radiotherapy (ART) for extrahepatic cholangiocarcinoma (EHCC) and gallbladder carcinoma (GBC) is unclear, with conflicting results from nonrandomized studies. We reported a meta-analysis to determine the impact of adjuvant radiotherapy on survival.MethodsPubMed, EMBASE, Cochrane Library and CNKI databases were searc...
Kamran, Sophia C. Coroller, Thibaud Milani, Nastaran Agrawal, Vishesh Baldini, Elizabeth H. Chen, Aileen B. Johnson, Bruce E. Kozono, David Franco, Idalid Chopra, Nitish
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Published in
Radiation Oncology
IntroductionLimited stage small cell lung cancer (LS-SCLC) has a poor prognosis. Additional prognostic markers are needed for risk-stratification and treatment intensification. This study compares quantitative CT-based volumetric tumor measurements versus International Association for the Study of Lung Cancer (IASLC) TNM staging to predict outcomes...
Scorsetti, Marta Cozzi, Luca Navarria, Pierina Fogliata, Antonella Rossi, Alexia Franceschini, Davide De Rose, Fiorenza Franzese, Ciro Carlo-Stella, Carmelo Santoro, Armando
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Published in
Radiation Oncology
BackgroundTo investigate the role of intensity modulated proton therapy (IMPT) compared to volumetric modulated arc therapy (VMAT) for advanced supradiaphragmatic Hodgkin’s lymphoma (HL) in young female patients by assessing dosimetric features and modelling the risk of treatment related complications and radiation-induced secondary malignancies.Me...
de Jong, R. Visser, J. Crama, K. F. van Wieringen, N. Wiersma, J. Geijsen, E. D. Bel, A.
Published in
Radiation Oncology
BackgroundTo compare target coverage and dose to the organs at risk in two approaches to rectal cancer: a clinically implemented adaptive radiotherapy (ART) strategy using plan selection, and a non-adaptive (non-ART) strategy.MethodsThe inclusion of the first 20 patients receiving adaptive radiotherapy produced 10 patients with a long treatment sch...
Potemin, Sergey Kübler, Jens Uvarov, Ivan Wenz, Frederik Giordano, Frank
Published in
Radiation Oncology
BackgroundNeoadjuvant external-beam radiotherapy (EBRT) with concomitant chemotherapy is the current standard-of-care for locally-advanced rectal cancer. Intraoperative radiotherapy (IORT) is to date only recommended for pelvic recurrences or incompletely resectable tumors. We here report on patients with stage II/III rectal cancer that were treate...
Sun, Jing Ouyang, Can Chang, Xiaoyun Zhang, Aimin Wang, Quan Li, Wengang Zhang, Dan Wang, Jia Li, Dong Duan, Xuezhang
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Published in
Radiation Oncology
BackgroundTo explore the survival and side effects of repeated CyberKnife stereotactic body radiation therapy (CK-SBRT) on hepatocellular carcinoma patients.Methods24 HCC patients were collected at The Fifth Medical Center of PLA General Hospital from November 2011 to July 2016. They received second-course CK-SBRT with a prescribed dose of 50(48–55...
Tang, Yang Yang, Li Qin, Wan Yi, Min’ Xiao Liu, Bo Yuan, Xiang’Lin
Published in
Radiation Oncology
BackgroundHomeodomain-interacting protein kinase 2 (HIPK2) has increasingly drawn attention as recent researches demonstrated its unique role in the regulation of multiple fundamental processes such as apoptosis, proliferation and DNA damage repair. Most importantly, HIPK2 was shown to play regulatory role in inflammation and influence the phenotyp...
Bacala, Angelina M.
Published in
Radiation Oncology
BackgroundIn Monte Carlo simulations, the fine-tuning of linac beam parameters to produce a good match between simulated and measured dose profiles is a lengthy, time-consuming and resource-intensive process. The objective of this study is to utilize the results of the gamma-index analysis toolkit embedded inside the windows-based PRIMO software pa...
Schüttrumpf, Lars Marschner, Sebastian Scheu, Katrin Hess, Julia Rietzler, Sibylle Walch, Axel Baumeister, Philipp Kirchner, Thomas Ganswindt, Ute Zitzelsberger, Horst
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Published in
Radiation Oncology
BackgroundDefinitive chemoradiotherapy (dCRT) is a standard treatment for patients with locally advanced head and neck cancer. There is a clinical need for a stratification of this prognostically heterogeneous group of tumors in order to optimize treatment of individual patients. We retrospectively reviewed all patients with head and neck squamous ...
Saager, Maria Glowa, Christin Peschke, Peter Brons, Stephan Grün, Rebecca Scholz, Michael Debus, Jürgen Karger, Christian P.
Published in
Radiation Oncology
BackgroundTo determine the relative biological effectiveness (RBE) and α/β-values after fractionated carbon ion irradiations of the rat spinal cord with varying linear energy transfer (LET) to benchmark RBE-model calculations.Material and methodsThe rat spinal cord was irradiated with 6 fractions of carbon ions at 6 positions within a 6 cm spread-o...
