Chea, Michel Fezzani, Karen Jacob, Julian Cuttat, Marguerite Croisé, Mathilde Simon, Jean-Marc Feuvret, Loïc Valery, Charles-Ambroise Maingon, Philippe Benadjaoud, Mohamed-Amine
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Published in
Radiation Oncology
PurposeTo compare linac-based mono-isocentric radiosurgery with Brainlab Elements Multiple Brain Mets (MBM) SRS and the Gamma Knife using a specific statistical method and to analyze the dosimetric impact of the target volume geometric characteristics. A dose fall-off analysis allowed to evaluate the Gradient Index relevancy for the dose spillage c...
Schneider, Raik Gademann, Günther Ochel, Hans-Joachim Neumann, Karsten Jandrig, Burkhard Hass, Peter Walke, Mathias Schostak, Martin Brunner, Thomas Christoph, Frank
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Published in
Radiation Oncology
BackgroundEpidermal Growth Factor Receptor is often overexpressed in advanced prostate carcinoma. In-vitro-studies in prostate carcinoma cell line DU145 have demonstrated increased sensibility to radiation after cetuximab treatment, but clinical data are not sufficient to date.MethodsWe analyzed effects of radiation and cetuximab in DU145 and A431 ...
Xu, Qing-Qing Lai, Yan-Zhen Huang, Zi-Lu Zeng, Zi-Yi Zhang, Ya-Ni Ou, Rui-Yao Wu, Wen-Min Chen, Lei Lu, Li-Xia
Published in
Radiation Oncology
ObjectivesThe study aims to analyze the clinical characteristics of head and neck mucosal melanoma (MMHN) and the effects of multiple treatment modalities on distant metastasis, recurrence and survival rates to provide a reference for the individualized treatment of MMHN.MethodsWe retrospectively reviewed 262 patients with stage III–IVb MMHN treate...
Uto, Megumi Ogura, Kengo Katagiri, Tomohiro Takehana, Keiichi Mizowaki, Takashi
Published in
Radiation Oncology
BackgroundThe risk for radiation necrosis is lower in fractionated stereotactic radiotherapy (SRT) than in conventional radiotherapy, and 13-fraction SRT is our method of choice for the treatment of brain metastases ≥ around 2 cm or patients who are expected to have a good prognosis. As 13-fraction SRT lasts for at least 17 days, adaptive radiother...
Gong, Hao Tao, Shengzhen Gagneur, Justin D. Liu, Wei Shen, Jiajian McCollough, Cynthia H. Hu, Yanle Leng, Shuai
Published in
Radiation Oncology
BackgroundMega-voltage fan-beam Computed Tomography (MV-FBCT) holds potential in accurate determination of relative electron density (RED) and proton stopping power ratio (SPR) but is not widely available.ObjectiveTo demonstrate the feasibility of MV-FBCT using a medical linear accelerator (LINAC) with a 2.5 MV imaging beam, an electronic portal im...
de Jong, Rianne Visser, Jorrit van Wieringen, Niek Wiersma, Jan Geijsen, Debby Bel, Arjan
Published in
Radiation Oncology
BackgroundOnline adaptive radiotherapy has the potential to reduce toxicity for patients treated for rectal cancer because smaller planning target volumes (PTV) margins around the entire clinical target volume (CTV) are required. The aim of this study is to describe the first clinical experience of a Conebeam CT (CBCT)-based online adaptive workflo...
Hirashima, Hideaki Nakamura, Mitsuhiro Baillehache, Pascal Fujimoto, Yusuke Nakagawa, Shota Saruya, Yusuke Kabasawa, Tatsumasa Mizowaki, Takashi
Published in
Radiation Oncology
BackgroundThis study aimed to (1) develop a fully residual deep convolutional neural network (CNN)-based segmentation software for computed tomography image segmentation of the male pelvic region and (2) demonstrate its efficiency in the male pelvic region.MethodsA total of 470 prostate cancer patients who had undergone intensity-modulated radiothe...
Da Silva Mendes, Vanessa Nierer, Lukas Li, Minglun Corradini, Stefanie Reiner, Michael Kamp, Florian Niyazi, Maximilian Kurz, Christopher Landry, Guillaume Belka, Claus
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Published in
Radiation Oncology
BackgroundThe aim of this study was to evaluate and compare the performance of intensity modulated radiation therapy (IMRT) plans, planned for low-field strength magnetic resonance (MR) guided linear accelerator (linac) delivery (labelled IMRT MRL plans), and clinical conventional volumetric modulated arc therapy (VMAT) plans, for the treatment of ...
Shen, Zhengwen Tan, Xia Li, Shi Tian, Xiumei Luo, Huanli Wang, Ying Jin, Fu
Published in
Radiation Oncology
BackgroundBoth patient-specific dose recalculation and γ passing rate analysis are important for the quality assurance (QA) of intensity modulated radiotherapy (IMRT) plans. The aim of this study was to analyse the correlation between the γ passing rates and the volumes of air cavities (Vair) and bony structures (Vbone) in target volume of head and...
Xu, Xin Sun, Zhi-Yong Wu, Hua-Wei Zhang, Chen-Peng Hu, Bin Rong, Ling Chen, Hai-Yan Xie, Hua-Ying Wang, Yu-Ming Lin, Hai-Ping
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Published in
Radiation Oncology
BackgroundNeoadjuvant chemoradiotherapy (nCRT) followed by surgery is a currently widely used strategy for locally advanced esophageal cancer (EC). However, the conventional imaging methods have certain deficiencies in the evaluation and prediction of the efficacy of nCRT. This study aimed to explore the value of functional imaging in predicting th...
