Yu, Hua Ni, Peiyan Tian, Yang Zhao, Liansheng Li, Mingli Li, Xiaojing Wei, Wei Wei, Jinxue Du, Xiangdong Wang, Qiang
...
Published in
Psychological medicine
Inflammation plays a crucial role in the pathogenesis of major depressive disorder (MDD) and bipolar disorder (BD). This study aimed to examine whether the dysregulation of complement components contributes to brain structural defects in patients with mood disorders. A total of 52 BD patients, 35 MDD patients, and 53 controls were recruited. The hu...
Kuo, Susan S Ventura, Joseph Forsyth, Jennifer K Subotnik, Kenneth L Turner, Luana R Nuechterlein, Keith H
Published in
Psychological medicine
Cognitive development after schizophrenia onset can be shaped by interventions such as cognitive remediation, yet no study to date has investigated whether patterns of early behavioral development may predict later cognitive changes following intervention. We therefore investigated the extent to which premorbid adjustment trajectories predict cogni...
Kendler, Kenneth S Lönn, Sara L Ektor-Andersen, John Sundquist, Jan Sundquist, Kristina
Published in
Psychological medicine
We need to better understand the frequency and predictors of opioid use disorder (OUD) after first opioid prescription (OP). We followed 1 516 392 individuals from the Swedish population born 1980-2000, from 1 July 2007, until 31 Dec 2017. We examined putative risk predictors with univariable and multivariable Cox Models and the potential causal ef...
Deng, Yanjia Gong, Ping Han, Shuguang Zhang, Jingyu Zhang, Shuai Zhang, Bin Lin, Yong Xu, Kai Wen, Ge Liu, Kai
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Published in
Psychological medicine
Previous studies have confirmed that miR-146a-5p overexpression suppresses neurogenesis, thereby enhancing depression-like behaviors. However, it remains unclear how miR-146a-5p dysregulation produces in vivo brain structural abnormalities in patients with major depressive disorder (MDD). In this case-control study, we combined cortical morphology ...
Hawes, Mariah T Schwartz, H Andrew Son, Youngseo Klein, Daniel N
Published in
Psychological medicine
This study leveraged machine learning to evaluate the contribution of information from multiple developmental stages to prospective prediction of depression and anxiety in mid-adolescence. A community sample (N = 374; 53.5% male) of children and their families completed tri-annual assessments across ages 3-15. The feature set included several impor...
Nichter, Brandon Koller, Dora De Angelis, Flavio Wang, Jiawei Girgenti, Matthew J Na, Peter J Hill, Melanie L Norman, Sonya B Krystal, John H Gelernter, Joel
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Published in
Psychological medicine
Little is known about environmental factors that may influence associations between genetic liability to suicidality and suicidal behavior. This study examined whether a suicidality polygenic risk score (PRS) derived from a large genome-wide association study (N = 122,935) was associated with suicide attempts in a population-based sample of Europea...
Levin-Aspenson, Holly Frances Zimmerman, Mark
Published in
Psychological medicine
Quantitatively derived dimensional models of psychopathology enjoy overwhelming empirical support, and a large and active community of psychopathology researchers has been establishing an empirically based dimensional hierarchical taxonomy of psychopathology (or HiTOP) as a strong candidate replacement for the current categorical classification sys...
de Haan, Lieuwe van Tricht, Mirjam van Dijk, Floor Arango, Celso Díaz-Caneja, Covadonga M Bobes, Julio García-Álvarez, Leticia Leucht, Stefan
Published in
Psychological medicine
Subjective response (SR) to antipsychotic medication is relevant for quality of life, adherence and recovery. Here, we evaluate (1) the extent of variation in SR in patients using a single antipsychotic; (2) the association between subjective and symptomatic response; and (3) predictors of SR. Open-label, single treatment condition with amisulpride...
Yunitri, Ninik Chu, Hsin Kang, Xiao Linda Wiratama, Bayu Satria Lee, Tso-Ying Chang, Li-Fang Liu, Doresses Kustanti, Christina Yeni Chiang, Kai-Jo Chen, Ruey
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Published in
Psychological medicine
Evidence on the long-term comparative effectiveness of posttraumatic stress disorder (PTSD) psychotherapies in adults remains unknown. Therefore, we performed an extensive network meta-analysis of randomised controlled trials (RCTs) to determine the comparative effectiveness of psychotherapies for people diagnosed with PTSD. A comprehensive search ...
Ju, Yumeng Wang, Mi Liu, Jin Liu, Bangshan Yan, Danfeng Lu, Xiaowen Sun, Jinrong Dong, Qiangli Zhang, Liang Guo, Hua
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Published in
Psychological medicine
Treatment non-response and recurrence are the main sources of disease burden in major depressive disorder (MDD). However, little is known about its neurobiological mechanism concerning the brain network changes accompanying pharmacotherapy. The present study investigated the changes in the intrinsic brain networks during 6-month antidepressant trea...
