Worley, Nicholas B Hill, Matthew N Christianson, John P
Published in
Progress in neuro-psychopharmacology & biological psychiatry
Stressor exposure is a predisposing risk factor for many psychiatric conditions such as PTSD and depression. However, stressors do not influence all individuals equally and in response to an identical stressor some individuals may be vulnerable while others are resilient. While various biological and behavioral factors contribute to vulnerability v...
Lai, Shenghan Heaphy, Christopher M Rizzo, Anthony J Celentano, David D Gerstenblith, Gary Li, Ji Moore, Richard D Treisman, Glenn Chen, Shaoguang Foster, Parker
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Published in
Progress in neuro-psychopharmacology & biological psychiatry
Our findings suggest that cocaine use may promote premature aging in HIV-infected individuals who are on ART. Our results emphasize the importance of cocaine abstinence/reduced use, which may retard HIV-associated premature aging.
He, Qinghua Huang, Xiaolu Turel, Ofir Schulte, Marya Huang, David Thames, April Bechara, Antoine Hser, Yih-Ing
Published in
Progress in neuro-psychopharmacology & biological psychiatry
Cumulative evidence suggests that cocaine use could alter the structure and function of different brain systems. However, the extent to which the altered brain structure and function possibly recover over time after cocaine abstinence remains less clear. The present study examines 39 male military veterans with different stages of cocaine addiction...
Canever, L Freire, T G Mastella, G A Damázio, L Gomes, S Fachim, I Michels, C Carvalho, G Godói, A K Peterle, B R
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Published in
Progress in neuro-psychopharmacology & biological psychiatry
A deficiency of maternal folic acid (FA) can compromise the function and development of the brain, and may produce a susceptibility to diseases such as schizophrenia (SZ) in the later life of offspring. The aim of this study was to evaluate the effects of both FA deficient and FA supplemented diets during gestation and lactation on behavioural para...
Keshavarzian, Elnaz Ghasemzadeh, Zahra Rezayof, Ameneh
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Progress in neuro-psychopharmacology & biological psychiatry
Stress seems to be an important risk factor in the beginning and continuing stages of cigarette tobacco smoking in humans. Considering that both of nicotine administration and stress exposure affect cognitive functions including memory formation, the aim of the present study was 1) to evaluate the effect of subcutaneous (s.c.) administration of nic...
Yenkoyan, Konstantin Fereshetyan, Katarine Matinyan, Senik Chavushyan, Vergine Aghajanov, Michail
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Progress in neuro-psychopharmacology & biological psychiatry
The increased levels of major brain monoamines in the model of AD supports the hypothesis of the important role of monoamines in the excessive synaptic excitation resulting in cognitive dysfunction in AD brain. The neuroprotective effect of PRP-1 as manifested by the recovery of monoaminergic system suggests this bioactive compound as a perspective...
Liemburg, E J Nolte, I M Klein, H C Knegtering, H
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Progress in neuro-psychopharmacology & biological psychiatry
This study in a large patient-group confirmed that inflammatory markers are related to psychotic disorders, particularly negative symptoms. Future studies could use more precise measures of inflammatory markers and measure symptomatic state at specific moments in illness progression.
Hayley, Amie C Green, Maja Downey, Luke A Stough, Con K K Keane, Michael Shiferaw, Brook Kostakis, Panagiota Shehabi, Yahya
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Progress in neuro-psychopharmacology & biological psychiatry
Ketamine hydrochloride elicits potent psychotomimetic and neurobehavioural effects which make it incompatible with driving; however, the direct effect on driving performance is yet to be assessed. Using an open label, within-subjects protocol, 15 males and 5 females (mean age = 30.8 years) were administered three fixed, stepwise increasing sub-anae...
Abdel Rasheed, Nora O El Sayed, Nesrine S El-Khatib, Aiman S
Published in
Progress in neuro-psychopharmacology & biological psychiatry
Alzheimer's disease (AD) is portrayed by progressive cognitive decline and pathological deposition of amyloid plaques as well as neurofibrillary tangles. Most of AD cases are sporadic, resulting from overlap of various environmental and genetic factors. Intra-cerebroventricular injection of streptozotocin (STZ) leads to insulin resistance brain sta...
Pereira, Lícia P Köhler, Cristiano A Stubbs, Brendon Miskowiak, Kamilla W Morris, Gerwyn de Freitas, Bárbara P Thompson, Trevor Fernandes, Brisa S Brunoni, André R Maes, Michael
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Published in
Progress in neuro-psychopharmacology & biological psychiatry
Imaging genetics studies involving participants with major depressive disorder (MDD) have expanded. Nevertheless, findings have been inconsistent. Thus, we conducted a systematic review and meta-analysis of imaging genetics studies that enrolled MDD participants across major databases through June 30th, 2017. Sixty-five studies met eligibility crit...
