Kaufmann, Priska Ort, Marion Golor, Georg Kornberger, Rüdiger Dingemanse, Jasper
Published in
Progress in neuro-psychopharmacology & biological psychiatry
Compounds that selectively target orexin-1 receptors may be beneficial for the treatment of various disorders. The role of selective orexin-1 receptor antagonists (1-SORAs) in addictive behavior and stress/anxiety-related disturbances has been demonstrated in animals. ACT-539313, an orally active, potent 1-SORA, has been assessed in a clinical sing...
Gill, Hartej Perez, Carlos D Gill, Barjot El-Halabi, Sabine Lee, Yena Lipsitz, Orly Park, Caroline Mansur, Rodrigo B Rodrigues, Nelson B McIntyre, Roger S
...
Published in
Progress in neuro-psychopharmacology & biological psychiatry
Fibromyalgia (FM) is a condition associated with chronic pain in muscles and soft tissues. Extant literature has demonstrated an association between FM, mood symptoms and suicidal behaviour. This systematic review aims to synthesize available literature assessing the prevalence of suicidality in FM populations and qualitatively review the included ...
Ruiz-Gonzalez, Cristofer Roman, Pablo Rueda-Ruzafa, Lola Rodriguez-Arrastia, Miguel Cardona, Diana
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Progress in neuro-psychopharmacology & biological psychiatry
Dementia is a chronic syndrome characterized by cognitive and behavioral symptoms, which may include short-term memory impairment and problems related to orientation, language, attention and perception. Although cognitive impairment (CI) is increasingly considered the main geriatric condition predisposing to dementia, its early management could sti...
Clémence-Fau, Martine Schwan, Raymund Angioi-Duprez, Karine Laprévote, Vincent Schwitzer, Thomas
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Progress in neuro-psychopharmacology & biological psychiatry
Mood disorders are particularly common, disabling conditions. Diagnosis can be difficult as it may involve different pathophysiological assumptions. This could explain why such disorders are resistant to treatment. The retina is part of the central nervous system and shares a common embryonic origin with the brain. Optical coherence tomography (OCT...
Kim, Hyun Joon Kang, Nyeonju
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Progress in neuro-psychopharmacology & biological psychiatry
Alcohol use disorder is one of the common substance use disorders leading to mental and health problems. Despite the potential positive effects of transcranial direct current stimulation (tDCS) on symptoms of various substance use disorder, how specific tDCS protocols effectively influence on individuals with alcohol use disorder is still controver...
Moon, Eunsoo Lavin, Paola Storch, Kai-Florian Linnaranta, Outi
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Progress in neuro-psychopharmacology & biological psychiatry
Antipsychotics are widely used to treat psychiatric illness and insomnia. However, the etiology of insomnia is multifactorial, including disrupted circadian rhythms. Several studies show that antipsychotics might modulate even healthy circadian rhythms. The purpose of this systematic review is to integrate current knowledge about the effects of ant...
Ait Chait, Yasmina Mottawea, Walid Tompkins, Thomas A Hammami, Riadh
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Progress in neuro-psychopharmacology & biological psychiatry
Emerging evidence highlighted the essential role played by the microbiota-gut-brain axis in maintaining human homeostasis, including nutrition, immunity, and metabolism. Much recent work has linked the gut microbiota to many psychiatric and neurodegenerative disorders such as depression, schizophrenia, and Alzheimer's disease. Shared gut microbiota...
Tsujii, Noa Mikawa, Wakako Adachi, Toru Sakanaka, Soichiro Shirakawa, Osamu
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Progress in neuro-psychopharmacology & biological psychiatry
Patients with remitted major depressive disorder (rMDD) generally rely on maladaptive coping strategies for stressful situations. These maladaptive copings are associated with an elevated relapse risk of rMDD; however, their neural basis remains poorly understood. We enrolled (1) 45 patients with rMDD (17-item Hamilton Depression Rating Scale [HRSD...
Dong, Haohao Wang, Ming Zheng, Hui Zhang, Jialin Dong, Guang-Heng
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Progress in neuro-psychopharmacology & biological psychiatry
Individuals with internet gaming disorder (IGD) usually report a higher sense of loneliness. Although studies have suggested a key role of the prefrontal cortex-based resting-state functional connectivity (rsFC) in both IGD and loneliness, the potential mechanism between IGD and loneliness remains unclear. Fifty-seven IGD and 81 matched recreationa...
Hill, Aron T Zomorrodi, Reza Hadas, Itay Farzan, Faranak Voineskos, Daphne Throop, Alanah Fitzgerald, Paul B Blumberger, Daniel M Daskalakis, Zafiris J
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Progress in neuro-psychopharmacology & biological psychiatry
Magnetic seizure therapy (MST) is emerging as a safe and well-tolerated experimental intervention for major depressive disorder (MDD), with very minimal cognitive side-effects. However, the underlying mechanism of action of MST remains uncertain. Here, we used resting-state electroencephalography (RS-EEG) to characterise the physiological effects o...
