Campos, Gabriela Munis Américo, Monique Ferrary Dos Santos Freitas, Andria Barroso, Fernanda Alvarenga Lima da Cruz Ferraz Dutra, Joyce Quaresma, Ludmila Silva Cordeiro, Bárbara Fernandes Laguna, Juliana Guimarães de Jesus, Luís Cláudio Lima Fontes, Aparecida Maria
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Probiotics and antimicrobial proteins
Target delivery of therapeutic agents with anti-inflammatory properties using probiotics as delivery and recombinant protein expression vehicles is a promising approach for the prevention and treatment of many diseases, such as cancer and intestinal immune disorders. Lactococcus lactis, a Lactic Acid Bacteria (LAB) widely used in the dairy industry...
Olímpio, Fabiana Andreata-Santos, Robert Rosa, Paloma Cristina Santos, Wellington Oliveira, Carlos Aimbire, Flavio
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Probiotics and antimicrobial proteins
Individuals with chronic obstructive pulmonary disease (COPD) are more susceptible to exacerbation crisis triggered by secondary lung infections due to the dysfunction of antiviral signaling, principally via suppression of IFN-γ. Although the probiotic is known for controlling pulmonary inflammation in COPD, the influence of the Lactobacillus rhamn...
Liang, Bing Xing, Dongming
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Probiotics and antimicrobial proteins
With the emphasis on intestinal health, probiotics have exploded into a vast market potential. However, new scientific evidence points out that the beneficial health benefits of probiotics are not necessarily directly related to viable bacteria. However, the metabolites or bacterial components of the live bacteria are the driving force behind healt...
Mohd Fuad, Aalina Sakiinah Amran, Nurul Aqilah Nasruddin, Nurrul Shaqinah Burhanudin, Nor Aszlitah Dashper, Stuart Arzmi, Mohd Hafiz
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Probiotics and antimicrobial proteins
Oral carcinogenesis is preceded by oral diseases associated with inflammation such as periodontitis and oral candidiasis, which are contributed by chronic alcoholism, smoking, poor oral hygiene, and microbial infections. Dysbiosis is an imbalance of microbial composition due to oral infection, which has been reported to contribute to oral carcinoge...
Lee, Ji Yeon Kang, Ju-Hui Jung, Ye-Rin Kang, Chang-Ho
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Probiotics and antimicrobial proteins
Allergic inflammation refers to a hyperimmune reaction that causes hypersensitivity responses such as hives, itchiness, runny nose, and cough due to specific allergens. Allergic diseases are known to be influenced by the diversity and distribution of intestinal microbiota, and Lactobacill is known to relieve allergic symptoms by modulating cytokine...
Mollazadeh-Narestan, Zahra Yavarikia, Parisa Homayouni-Rad, Aziz Samadi Kafil, Hossein Mohammad-Alizadeh-Charandabi, Sakineh Gholizadeh, Pourya Mirghafourvand, Mojgan
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Probiotics and antimicrobial proteins
Vaginitis is a common problem in women. Candida albicans is responsible for more than 85% of vaginal fungal infections. The aim of this study was to compare the effects of probiotic and fluconazole on the treatment and recurrence of vulvovaginal candidiasis (VVC). This triple-blinded randomized controlled trial was conducted on 80 married women, ag...
Ivashkin, Vladimir Fomin, Victor Moiseev, Sergey Brovko, Michail Maslennikov, Roman Ulyanin, Anatoly Sholomova, Victoria Vasilyeva, Maria Trush, Elizaveta Shifrin, Oleg
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Probiotics and antimicrobial proteins
The treatment of coronavirus disease (COVID-19) and COVID-19-associated diarrhea remains challenging. This study aimed to evaluate the efficacy of a multi-strain probiotic in the treatment of COVID-19. This was a randomized, controlled, single-center, open-label trial (NCT04854941). Inpatients with confirmed COVID-19 and pneumonia were randomly ass...
Lucas, Douglas Ribeiro Damica, Filipe Zaniratti Toledo, Estefany Braz Cogo, Antônio Jesus Dorighetto Okorokova-Façanha, Anna Lvovna Gomes, Valdirene Moreira de Oliveira Carvalho, André
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Probiotics and Antimicrobial Proteins
The management of fungal diseases imposes an urgent need for the development of effective antifungal drugs. Among new drug candidates are the antimicrobial peptides, and especially their derivatives. Here, we investigated the molecular mechanism of action of three bioinspired peptides against the opportunistic yeasts Candida tropicalis and Candida ...
Rebaza-Cardenas, Teresa D Silva-Cajaleón, Kenneth Sabater, Carlos Delgado, Susana Montes-Villanueva, Nilda D Ruas-Madiedo, Patricia
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Probiotics and antimicrobial proteins
In this work, two Peruvian beverages "Masato de Yuca," typical of the Amazonian communities made from cassava (Manihot esculenta), and "Chicha de Siete Semillas," made from different cereal, pseudo-cereal, and legume flours, were explored for the isolation of lactic acid bacteria after obtaining the permission of local authorities following Nagoya ...
Butt, Usman Dawood Khan, Sumaikah Liu, Xiaowan Sharma, Awkash Zhang, Xiaoqin Wu, Bin
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Probiotics and Antimicrobial Proteins
Streptomyces is a Gram-positive bacterium, belonging to the family Streptomycetaceae and order Streptomycetales. Several strains from different species of Streptomyces can be used to promote the health and growth of artificially cultured fish and shellfish by producing secondary metabolites including antibiotics, anticancer agents, antiparasitic ag...