Desjardins, Leandra Hancock, Kelly Szatmari, Peter Alexander, Sarah Shama, Wendy De Souza, Claire Mills, Denise Abla, Oussama Barrera, Maru
Published in
Pilot and Feasibility Studies
BackgroundA pediatric cancer diagnosis and its treatment can have a detrimental effect on the mental health of children and their families. Screening to identify psychosocial risk in families has been recognized as a standard of care in pediatric oncology, but there has been limited clinical application of this standard thus far. A significant impe...
Cooke, Noah C. A. Bala, Asem Allard, Johane P. Hota, Susy Poutanen, Susan Taylor, Valerie H.
Published in
Pilot and Feasibility Studies
BackgroundBipolar disorder (BD) is a chronic, debilitating illness with significant medical morbidity, often secondary to current treatments, and a high recurrence rate. This burden of disease reflects limitations in the tolerability and efficacy of current treatments. There is a compelling body of evidence linking the gut microbiota to mental illn...
Chiutsi-Phiri, Gabriella Kalimbira, Alexander A. Banda, Leonard Nalivata, Patson C. Sanuka, Marion Kalumikiza, Zione Matandika, Limbanazo Mfutso-Bengo, Joseph Allen, Elizabeth Ferguson, Elaine
...
Published in
Pilot and Feasibility Studies
BackgroundThis study reports findings from formative research conducted to assess the feasibility and inform the design and implementation of the Addressing Hidden Hunger with Agronomy (AHHA) trial. The AHHA trial was a randomised, controlled trial conducted in rural Malawi, in which participants were given maize flour biofortified with selenium or...
Wrottesley, Stephanie V. Pearson, Rebecca Prioreschi, Alessandra
Published in
Pilot and Feasibility Studies
BackgroundMany children in low- and middle-income countries lack the stimulation needed to support healthy growth and development. Sensitive interactions between caregivers and infants may promote healthy movement behaviours in infants, which could improve childhood growth and development. However, reliable measures for such interactions require te...
Tsakos, Georgios Brocklehurst, Paul R. Watson, Sinead Verey, Anna Goulden, Nia Jenkins, Alison Hoare, Zoe Pye, Kirstie Wassall, Rebecca R. Sherriff, Andrea
...
Published in
Pilot and Feasibility Studies
BackgroundEvidence for interventions promoting oral health amongst care home residents is weak. The National Institute for Health and Care Excellence (NICE) guideline NG48 aims to maintain and improve the oral health of care home residents. A co-design process that worked with residents and care home staff to understand how the NG48 guideline could...
Sera, Valerie A. Stevens, Ann E. Song, Howard K. Rodriguez, Victor M. Tibayan, Frederick A. Treggiari, Miriam M.
Published in
Pilot and Feasibility Studies
BackgroundUncontrolled bleeding after cardiac surgery can be life-threatening. Factor eight inhibitor bypassing activity (FEIBA) is a prothrombin complex concentrate empirically used as rescue therapy for correction of refractory bleeding diathesis post-cardiopulmonary bypass (CPB). FEIBA used as rescue therapy for bleeding diathesis after CPB has ...
Taubner, Svenja Hauschild, Sophie Kasper, Lea Kaess, Michael Sobanski, Esther Gablonski, Thorsten-Christian Schröder-Pfeifer, Paul Volkert, Jana
Published in
Pilot and Feasibility Studies
BackgroundConduct disorder (CD) is a complex mental disorder characterized by severe rule-breaking and aggressive behavior. While studies have shown that several therapeutic interventions are effective in treating CD symptoms, researchers call for treatments based on etiological knowledge and potential patho-mechanisms. Mentalization-based treatmen...
Ridge, Katie Conlon, Niall Hennessy, Martina Dunne, Pádraic J.
Published in
Pilot and Feasibility Studies
Graser, Judith V. Bastiaenen, Caroline H. G. Gut, Anja Keller, Urs van Hedel, Hubertus J. A.
Published in
Pilot and Feasibility Studies
IntroductionEvidence about contextual interference in children with brain lesions when practising motor tasks is lacking. Our main objective was to evaluate the feasibility of a randomised controlled trial (RCT) comparing blocked with random practice order of an upper limb robotic exergame to improve reaching in children with neuromotor disorders w...
Macedo, Luciana G. Richardson, Julie Battie, Michele C. Hancock, Mark Kwan, Matthew Hladysh, Genevieve Zhuo, Linda
Published in
Pilot and Feasibility Studies
BackgroundLow back pain (LBP) is a long-term health condition with an unpredictable pattern of symptomatic episodes, remission, and recurrence. Recently published systematic reviews suggest that exercise is the most effective intervention for preventing recurrences of LBP in persons that have recovered. Similar programs may also be effective in pre...
