Whittemore, Robin Vilar-Compte, Mireya Burrola-Méndez, Soraya Lozano-Marrufo, Annel Delvy, Roberta Pardo-Carrillo, Mariana De La Cerda, Selene Pena-Purcell, Ninfa Pérez-Escamilla, Rafael
Published in
Pilot and Feasibility Studies
BackgroundType 2 diabetes (T2D) is a public health pandemic disproportionately affecting low- and middle-income countries. The purpose of this formative research was to adapt evidence-based diabetes self-management education programs to the context of Seguro Popular clinics in Mexico. A theory-based mHealth (pictorial text messaging) component was ...
Armstrong-Buisseret, Lindsay Godolphin, Peter J. Bradshaw, Lucy Mitchell, Eleanor Ratcliffe, Sam Storey, Claire Heazell, Alexander E. P.
Published in
Pilot and Feasibility Studies
BackgroundBiomarkers of placental function can potentially aid the diagnosis and prediction of pregnancy complications. This randomised controlled pilot trial assessed whether for women with reduced fetal movement (RFM), intervention directed by the measurement of a placental biomarker in addition to standard care was feasible and improved pregnanc...
Salami, Kolawole Imbault, Nathalie Erlebach, Aljoscha Urban, Johanna Zoglowek, Mike Tornieporth, Nadia G.
Published in
Pilot and Feasibility Studies
BackgroundWe sought to develop and test an objective scorecard-based system for assessing and categorizing available research sites in Lassa fever-affected countries based on their preparedness and capability to host Lassa fever vaccine clinical trials.MethodsWe mapped available clinical research sites through interrogation of online clinical trial...
Tucker, Wesley J. Thomas, Binu P. Puzziferri, Nancy Samuel, T. Jake Zaha, Vlad G. Lingvay, Ildiko Almandoz, Jaime Wang, Jing Gonzales, Edward A. Brothers, R. Matthew
...
Published in
Pilot and Feasibility Studies
BackgroundBariatric surgery is an effective long-term weight loss strategy yielding improvements in neurocognitive function; however, the mechanism(s) responsible for these improvements remains unclear. Here, we assessed the feasibility of using magnetic resonance imaging (MRI) to evaluate whether cerebral vascular reactivity (CVR) is impaired in s...
Pellecchia, Melanie Beidas, Rinad S. Mandell, David S. Cannuscio, Carolyn C. Dunst, Carl J. Stahmer, Aubyn C.
Published in
Pilot and Feasibility Studies
BackgroundParent-mediated early interventions (EI) for children with autism spectrum disorder (ASD) can result in significant improvements in children’s cognitive ability, social functioning, behavior, and adaptive skills, as well as improvements in parental self-efficacy and treatment engagement. The common component to efficacious parent-mediated...
Kong, Xue-Jun Liu, Jun Li, Jing Kwong, Kenneth Koh, Madelyn Sukijthamapan, Piyawat Guo, Jason J. Sun, Zhenyu Jim Song, Yiqing
Published in
Pilot and Feasibility Studies
BackgroundAutism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by impairments in social interaction and communication. Oxytocin (OXT), as a neuropeptide, plays a role in emotional and social behaviors. Lactobacillus reuteri (L. reuteri) supplementation led to an OXT-dependent behavioral improvement in ASD mouse mode...
Mantzari, Eleni Galloway, Catherine Hollands, Gareth Pechey, Rachel Zupan, Zorana Pilling, Mark Marteau, Theresa
Published in
Pilot and Feasibility Studies
BackgroundReducing alcohol consumption across populations would prevent many non-communicable diseases. Large packages increase food and non-alcoholic drink consumption and large glasses increase wine consumption. Smaller bottles may reduce alcohol consumption but their impact is uncertain. This study aims to (i) explore the feasibility and accepta...
Nsangi, Allen Semakula, Daniel Rosenbaum, Sarah E. Oxman, Andrew David Oxman, Matt Morelli, Angela Austvoll-Dahlgren, Astrid Kaseje, Margaret Mugisha, Michael Uwitonze, Anne-Marie
...
Published in
Pilot and Feasibility Studies
BackgroundPeople of all ages are flooded with health claims about treatment effects (benefits and harms of treatments). Many of these are not reliable, and many people lack skills to assess their reliability. Primary school is the ideal time to begin to teach these skills, to lay a foundation for continued learning and enable children to make well-...
Perra, Oliver Wass, Sam McNulty, Alison Sweet, David Papageorgiou, Kostas Johnston, Matthew Patterson, Aaron Bilello, Delfina Alderdice, Fiona
Published in
Pilot and Feasibility Studies
BackgroundChildren born preterm may display cognitive, learning, and behaviour difficulties as they grow up. In particular, very premature birth (gestation age between 28 and less than 32 weeks) may put infants at increased risk of intellectual deficits and attention deficit disorder. Evidence suggests that the basis of these problems may lie in di...
Hickey, Matthew D. Lisker, Sarah Brodie, Shauna Vittinghoff, Eric Russell, Marika D. Sarkar, Urmimala
Published in
Pilot and Feasibility Studies
BackgroundDespite recommendations for monitoring patients with chronic and high-risk conditions, gaps still remain. These gaps are exacerbated in outpatient care, where patients and clinicians face challenges related to care coordination, multiple electronic health records, and extensive follow-up. In addition, low-income and racial/ethnic minority...
