Kneepkens, Esther Wolfs, Cecile Wanders, Roel-Germ Traneus, Erik Eekers, Danielle Verhaegen, Frank
Published in
Physics in Medicine & Biology
Objective. The goal of the study was to test the hypothesis that shoot-through FLASH proton beams would lead to lower dose-averaged LET (LETD) values in critical organs, while providing at least equal normal tissue sparing as clinical proton therapy plans. Approach. For five neurological tumor patients, pencil beam scanning (PBS) shoot-through plan...
Ge, Gary R Song, Wei Nedergaard, Maiken Rolland, Jannick P Parker, Kevin J
Published in
Physics in Medicine & Biology
Huang, Chaoxing Wong, Vincent Wai-Sun Chan, Queenie Chu, Winnie Chiu-Wing Chen, Weitian
Published in
Physics in Medicine & Biology
Objective. Quantitative T1ρ imaging has potential for assessment of biochemical alterations of liver pathologies. Deep learning methods have been employed to accelerate quantitative T1ρ imaging. To employ artificial intelligence-based quantitative imaging methods in complicated clinical environment, it is valuable to estimate the uncertainty of the...
Dejene, Edengenet M Brenner, Winfried Makowski, Marcus R Kolbitsch, Christoph
Published in
Physics in Medicine & Biology
Objective. Physiological parameter estimation is affected by intrinsic ambiguity in the data such as noise and model inaccuracies. The aim of this work is to provide a deep learning framework for accurate parameter and uncertainty estimates for DCE-MRI in the liver. Approach. Concentration time curves are simulated to train a Bayesian neural networ...
Cockmartin, L Bosmans, H Marshall, N W
Published in
Physics in Medicine & Biology
The technique of dual-energy contrast enhanced mammography (CEM) visualizes iodine uptake in cancerous breast lesions following an intravenous injection of a contrast medium. The CEM image is generated by recombining two images acquired in rapid succession: a low energy image, with a mean energy below the iodine K-edge, and a higher energy image. T...
Marshall, N W Cockmartin, L Bosmans, H
Published in
Physics in Medicine & Biology
Part II of this study describes constancy tests for artefacts and image uniformity, exposure time, and phantom-based dosimetry; these are applied to four mammography systems equipped with contrast enhanced mammography (CEM) capability. Artefacts were tested using a breast phantom that simulated breast shape and thickness change at the breast edge. ...
Lin, Qisi Wu, Zhao Zan, Guibin Huang, Meng Dang, Zheng Tian, Lijiao Guan, Yong Liu, Gang Lu, Yalin Tian, Yangchao
...
Published in
Physics in Medicine & Biology
Objective. High energy and large field of view (FOV) phase contrast imaging is crucial for biological and even medical applications. Although some works have devoted to achieving a large FOV at high energy through bending gratings and so on, which would be extremely challenging in medical high energy imaging. Approach. We analyze the angular shadow...
Hao, Dechen Li, Hualing Zhang, Yonglai Zhang, Qi
Published in
Physics in Medicine & Biology
Objective. Accurate left atrial segmentation is the basis of the recognition and clinical analysis of atrial fibrillation. Supervised learning has achieved some competitive segmentation results, but the high annotation cost often limits its performance. Semi-supervised learning is implemented from limited labeled data and a large amount of unlabele...
Grutman, Tal Ilovitsh, Tali
Published in
Physics in Medicine & Biology
Objective. Develop a dense algorithm for calculating the speed-of-sound shift between consecutive acoustic acquisitions as a noninvasive means to evaluating temperature change during thermal ablation. Methods. An algorithm for dense speed-of-sound shift imaging (DSI) was developed to simultaneously incorporate information from the entire field of v...
Liu, Gang Zhao, Lewei Liu, Peilin Dao, Riao Qian, Yujia Cong, Xiaoda Janssens, Guillaume Li, Xiaoqiang Ding, Xuanfeng
Published in
Physics in Medicine & Biology
Objective. To investigate the impact of various delivery tolerance window settings on the treatment delivery time and dosimetric accuracy of spot-scanning proton arc (SPArc) therapy. Approach. SPArc plans were generated for three representative disease sites (brain, lung, and liver cancer) with an angle sampling frequency of 2.5°. An in-house dynam...
