Estimating the effectiveness of remdesivir on risk of COVID-19 mortality: The role of observational data.
Published in Pharmacological research
Estimating the effectiveness of remdesivir on risk of COVID-19 mortality: The role of observational data.
Clinical impact and disease evolution of SARS-CoV-2 infection in familial Mediterranean fever
Published in Pharmacological Research
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COVID-19 and the promise of small molecule therapeutics: Are there lessons to be learnt?
Published in Pharmacological research
The coronavirus disease 2019 (COVID-19) pandemic had grounded the world to a standstill. As the disease continues to rage two years on, it is apparent that effective therapeutics are critical for a successful endemic living with COVID-19. A dearth in suitable antivirals has prompted researchers and healthcare professionals to investigate existing a...
Timely treatment and higher compliance to traditional Chinese medicine: New influencing factors for reducing severe COVI...
Published in Pharmacological Research
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Kinsenoside attenuates liver fibro-inflammation by suppressing dendritic cells via the PI3K-AKT-FoxO1 pathway.
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Published in Pharmacological research
Kinsenoside (KD) exhibits anti-inflammatory and immunosuppressive effects. Dendritic cells (DCs) are critical regulators of the pathologic inflammatory milieu in liver fibrosis (LF). Herein, we explored whether and how KD repressed development of LF via DC regulation and verified the pathway involved in the process. Given our analysis, both KD and ...
Oncopreventive and oncotherapeutic potential of licorice triterpenoid compound glycyrrhizin and its derivatives: Molecul...
Published in Pharmacological Research
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Systemic administration of glucocorticoids, cardiovascular complications and mortality in patients hospitalised with COV...
Published in Pharmacological Research
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Xuanfei Baidu Decoction reduces acute lung injury by regulating infiltration of neutrophils and macrophages via PD-1/IL1...
Published in Pharmacological research
The pathogenic hyper-inflammatory response has been revealed as the major cause of the severity and death of the Corona Virus Disease 2019 (COVID-19). Xuanfei Baidu Decoction (XFBD) as one of the "three medicines and three prescriptions" for the clinically effective treatment of COVID-19 in China, shows unique advantages in the control of symptomat...
DNA aptamers masking angiotensin converting enzyme 2 as an innovative way to treat SARS-CoV-2 pandemic.
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Published in Pharmacological research
All the different coronavirus SARS-CoV-2 variants isolated so far share the same mechanism of infection mediated by the interaction of their spike (S) glycoprotein with specific residues on their cellular receptor: the angiotensin converting enzyme 2 (ACE2). Therefore, the steric hindrance on this cellular receptor created by a bulk macromolecule m...
Corrigendum to “DNA aptamers masking angiotensin converting enzyme 2 as an innovative way to treat SARS-CoV-2 pandemic”
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Published in Pharmacological Research
