Metabolic alkalosis in peritoneal dialysis - beyond the obvious: Questions.
Published in Pediatric nephrology (Berlin, Germany)
Metabolic alkalosis in peritoneal dialysis - beyond the obvious: Questions.
Thrombotic microangiopathy in children.
Published in Pediatric nephrology (Berlin, Germany)
The syndrome of thrombotic microangiopathy (TMA) is a clinical-pathological entity characterized by microangiopathic hemolytic anemia, thrombocytopenia, and end organ involvement. It comprises a spectrum of underlying etiologies that may differ in children and adults. In children, apart from ruling out shigatoxin-associated hemolytic uremic syndrom...
Anti-factor H antibody associated hemolytic uremic syndrome following SARS-CoV-2 infection.
Published in Pediatric nephrology (Berlin, Germany)
The pathogenesis of autoantibody generation in anti-factor H (FH) antibody associated atypical hemolytic uremic syndrome (aHUS) is unknown and is perhaps triggered by an infectious or environmental agent. We observed an unusual increase of patients with anti-FH antibody associated aHUS coinciding with the second pandemic wave in New Delhi and suspe...
Urothelial progenitors in development and repair.
Published in Pediatric nephrology (Berlin, Germany)
Urothelium is a specialized multilayer epithelium that lines the urinary tract from the proximal urethra to the kidney. In addition to proliferation and differentiation during development, urothelial injury postnatally triggers a robust regenerative capacity to restore the protective barrier between the urine and tissue. Mounting evidence supports ...
A child presents with acute kidney injury, alkalosis and hypercalcaemia-a new-age cause for a historical syndrome: Quest...
Published in Pediatric nephrology (Berlin, Germany)
Whole-exome sequencing and variant spectrum in children with suspected inherited renal tubular disorder: the East India ...
...Published in Pediatric nephrology (Berlin, Germany)
Inherited tubulopathies are a heterogeneous group of genetic disorders making whole-exome sequencing (WES) the preferred diagnostic methodology. This was a multicenter descriptive study wherein children (
A child presents with acute kidney injury, alkalosis and hypercalcaemia-a new-age cause for a historical syndrome: Answe...
Published in Pediatric nephrology (Berlin, Germany)
Factors associated with follow-up outside a transplant center among pediatric kidney transplant recipients.
Published in Pediatric nephrology (Berlin, Germany)
Transfer of follow-up care after pediatric kidney transplantation (KTx) may jeopardize quality of care and patient outcomes. We sought to determine if minority status and socioeconomic factors were associated with increased likelihood of follow-up outside a transplant center, and whether this transition of care was associated with worse long-term g...
Cystinuria: an update on pathophysiology, genetics, and clinical management.
Published in Pediatric nephrology (Berlin, Germany)
Cystinuria is the most common genetic cause of nephrolithiasis in children. It is considered a heritable aminoaciduria as the genetic defect affects the reabsorption of cystine and three other amino acids (ornithine, lysine, and arginine) in the renal proximal tubule. Patients affected by this condition have elevated excretion of cystine in the uri...
Furosemide and albumin for the treatment of nephrotic edema: a systematic review.
Published in Pediatric nephrology (Berlin, Germany)
Edema is one of the cardinal clinical features of nephrotic syndrome (NS). It may vary from mild periorbital edema to severe generalized edema (anasarca). In patients where edema does not improve with prednisone therapy, the most common supportive medications are diuretics and albumin. However, due to the complex pathophysiology of edema formation ...
