Published in International wound journal
Recent studies showed that mesenchymal stem cell (MSC) transplantation significantly alleviated tissue fibrosis; however, little is known about the efficacy on attenuating cutaneous scar formation. In this study, we established a dermal fibrosis model induced by bleomycin and evaluated the benefit of bone marrow-derived mesenchymal stem cells (BM-M...
Published in Pathologie-biologie
Published in Pathologie-biologie
Published in Pathologie-biologie
Published in Pathologie-biologie
Genes encoding the DNA helicase TWINKLE (C10orf2) or the two subunits of mtDNA polymerase γ (POLγ) (POLG1 and POLG2) have a direct effect on the mitochondrial DNA replication machinery and were reported in many mitochondrial disorders. Friedreich's ataxia (FRDA) is the common cause of ataxia often associated with the expansion of a GAA repeat in in...
Published in Pathologie Biologie
La longévité et le vieillissement sont sous le contrôle de mécanismes différents. La régulation de la longévité comporte un facteur génétique important, le vieillissement est essentiellement le résultat de mécanismes post-génétiques. Pour la longévité, des voies génétiques, sous le contrôle des sirtuines et la voie TOR ont attiré l’attention, après...
Published in Pathologie Biologie
AimThree forms of cutaneous leishmaniasis (CL) are endemic in Tunisia. The identification of the causative species is useful to complete epidemiological data and to manage the cases. The aim of this study is to assess PCR-RFLP technique in the identification of Leishmania species responsible of CL in Tunisia and to compare the results of this techn...
Published in Pathologie Biologie
Published in Pathologie Biologie
Published in Pathologie Biologie
