Wang, De-Ping Wang, Zhao-Jun Zhao, Rong Lin, Cai-Xia Sun, Qian-Yu Yan, Cai-Ping Zhou, Xin Cao, Ji-Min
Published in
Particle and Fibre Toxicology
BackgroundThe growing use of silica nanoparticles (SiNPs) in many fields raises human toxicity concerns. We studied the toxicity of SiNP-20 (particle diameter 20 nm) and SiNP-100 (100 nm) and the underlying mechanisms with a focus on the endothelium both in vitro and in vivo.MethodsThe study was conducted in cultured human umbilical vein endothelia...
Abdelkhaliq, Ashraf van der Zande, Meike Peters, Ruud J. B. Bouwmeester, Hans
Published in
Particle and Fibre Toxicology
BackgroundSilver nanoparticles (AgNPs) are used extensively in various consumer products because of their antimicrobial potential. This requires insight in their potential hazards and risks including adverse effects during pregnancy on the developing fetus. Using a combination of the BeWo b30 placental transport model and the mouse embryonic stem c...
Murugadoss, Sivakumar Brassinne, Frederic Sebaihi, Noham Petry, Jasmine Cokic, Stevan M. Van Landuyt, Kirsten L. Godderis, Lode Mast, Jan Lison, Dominique Hoet, Peter H.
...
Published in
Particle and Fibre Toxicology
BackgroundThe terms agglomerates and aggregates are frequently used in the regulatory definition(s) of nanomaterials (NMs) and hence attract attention in view of their potential influence on health effects. However, the influence of nanoparticle (NP) agglomeration and aggregation on toxicity is poorly understood although it is strongly believed tha...
Carll, Alex P. Salatini, Renata Pirela, Sandra V. Wang, Yun Xie, Zhengzhi Lorkiewicz, Pawel Naeem, Nazratan Qian, Yong Castranova, Vincent Godleski, John J.
...
Published in
Particle and Fibre Toxicology
BackgroundUsing engineered nanomaterial-based toners, laser printers generate aerosols with alarming levels of nanoparticles that bear high bioactivity and potential health risks. Yet, the cardiac impacts of printer-emitted particles (PEPs) are unknown. Inhalation of particulate matter (PM) promotes cardiovascular morbidity and mortality, and ultra...
Sironval, Violaine Scagliarini, Vittoria Murugadoss, Sivakumar Tomatis, Maura Yakoub, Yousof Turci, Francesco Hoet, Peter Lison, Dominique van den Brule, Sybille
Published in
Particle and Fibre Toxicology
BackgroundLi-ion batteries (LIB) are used in most portable electronics. Among a wide variety of materials, LiCoO2 (LCO) is one of the most used for the cathode of LIB. LCO particles induce oxidative stress in mouse lungs due to their Co content, and have a strong inflammatory potential. In this study, we assessed the mutagenic potential of LCO part...
Emam, Baharan Shahsavani, Abbas Khodagholi, Fariba Zarandi, Saeed Motesaddi Hopke, Philip K. Hadei, Mostafa Behbahani, Hamidreza Yarahmadi, Maryam
Published in
Particle and Fibre Toxicology
BackgroundEpidemiological studies have reported associations between elevated air pollution and autism spectrum disorders (ASD). However, we hypothesized that exposure to air pollution that mimics real world scenarios, is a potential contributor to ASD. The exact etiology and molecular mechanisms underlying ASD are not well understood. Thus, we ass...
Choi, Hye-Yeon Lee, Yong-Hoon Lim, Cheol-Hong Kim, Yong-Soon Lee, In-Seop Jo, Ji-Min Lee, Ha-Young Cha, Hyo-Geun Woo, Hee Jong Seo, Dong-Seok
...
Published in
Particle and Fibre Toxicology
BackgroundAlthough biocides at low concentrations have been used to control pests, they can be more harmful than industrial chemicals as humans are directly and frequently exposed to such biocides. Benzalkonium chloride (BAC or BKC) is a non-toxic substance used to control pests. Recently, BAC has been increasingly used as a component in humidifier...
Pardo, Michal Li, Chunlin He, Quanfu Levin-Zaidman, Smadar Tsoory, Michael Yu, Qingqing Wang, Xinming Rudich, Yinon
Published in
Particle and Fibre Toxicology
BackgroundCarbonaceous aerosols emitted from indoor and outdoor biomass burning are major risk factors contributing to the global burden of disease. Wood tar aerosols, namely, tar ball particles, compose a substantial fraction of carbonaceous emissions, especially from biomass smoldering. However, their health-related impacts and toxicity are still...
Walter, Martin Schenkeveld, Walter D. C. Geroldinger, Gerald Gille, Lars Reissner, Michael Kraemer, Stephan M.
Published in
Particle and Fibre Toxicology
BackgroundFibrous chrysotile has been the most commonly applied asbestos mineral in a range of technical applications. However, it is toxic and carcinogenic upon inhalation. The chemical reactivity of chrysotile fiber surfaces contributes to its adverse health effects by catalyzing the formation of highly reactive hydroxyl radicals (HO•) from H2O2....
Skovmand, Astrid Erdely, Aaron Antonini, James M. Nurkiewicz, Timothy R. Shoeb, Mohammad Eye, Tracy Kodali, Vamsi Loeschner, Katrin Vidmar, Janja Agerholm, Jørgen S.
...
Published in
Particle and Fibre Toxicology
BackgroundPrevious studies have shown that inhalation of welding fumes may induce pulmonary and systemic inflammation and organ accumulation of metal, to which spermatogenesis and endocrine function may be sensitive. Also obesity may induce low-grade systemic inflammation. This study aimed to investigate the effects on sperm production of inhaled m...
