Schliep, Karen C Feldkamp, Marcia L Hanson, Heidi A Hollingshaus, Michael Fraser, Alison Smith, Ken R Panushka, Katherine A Varner, Michael W
Published in
Paediatric and perinatal epidemiology
Fetal aneuploidy risk increases with maternal age, but the majority of pregnancies complicated by trisomy 21 occur in younger women. It has been suggested that grandmaternal and/or paternal age may also play a role. To assess the association between grandmaternal and paternal age and trisomy 21. For the grandmaternal assessments, we included all of...
Kapos, Flavia P White, Lauren A Schmidt, Kelsey A Hawes, Stephen E Starr, Jacqueline R
Published in
Paediatric and perinatal epidemiology
Orofacial clefts (OFC) have multifactorial aetiology. Established risk factors explain a small proportion of cases. To evaluate OFC risk by maternal rural residence and race/ethnicity, and test whether these associations changed after US-mandated folic acid fortification. This population-based case-control study included all non-syndromic OFC cases...
Wu, Han Zhao, Min Liang, Yajun Liu, Fangchao Xi, Bo
Published in
Paediatric and perinatal epidemiology
Both young and advanced maternal age have been associated with higher risks of neonatal mortality, but most studies are from high-income countries and the evidence from low- and middle-income countries (LMICs) is scarce. To investigate the association between maternal age at delivery and neonatal mortality in LMICs. This is a cross-sectional study ...
Ray, Joel G Berger, Howard Park, Alison L
Published in
Paediatric and perinatal epidemiology
Chronic placental inflammation is associated with preterm birth (PTB) and perinatal mortality. Ferritin is often elevated in chronic inflammatory conditions, but prior studies of its relation to PTB were restricted to ferritin measurement within pregnancy, were underpowered to detect rarer outcomes, and did not account for pre-existing maternal inf...
Heinke, Dominique Rich-Edwards, Janet W Williams, Paige L Hernandez-Diaz, Sonia Anderka, Marlene Fisher, Sarah C Desrosiers, Tania A Shaw, Gary M Romitti, Paul A Canfield, Mark A
...
Published in
Paediatric and perinatal epidemiology
Risk factors for birth defects are frequently investigated using data limited to liveborn infants. By conditioning on survival, results of such studies may be distorted by selection bias, also described as "livebirth bias." However, the implications of livebirth bias on risk estimation remain poorly understood. We sought to quantify livebirth bias ...
Jamaladin, Hussein van Rooij, Iris A L M van der Zanden, Loes F M van Gelder, Marleen M H J Roeleveld, Nel
Published in
Paediatric and perinatal epidemiology
Hypospadias is a frequently occurring congenital anomaly in male infants, in which the opening of the urethra is located along the ventral side of the penis. Although various studies attempted to identify its causes, the aetiology of the majority of hypospadias cases remains poorly understood. Maternal hypertensive disorders are believed to be asso...
Zhang, Xiao Gong, Yunhui Chen, Yue Corte, Karen Della Duan, Ruonan Tian, Guo Liang, Yi Xue, Hongmei Zhang, Jieyi Li, Ming
...
Published in
Paediatric and perinatal epidemiology
Pregnancy and birth cohorts addressing maternal nutrition and its impact on health outcomes have been rare in China, especially in Southwest China. To describe the design, implementation, baseline characteristics, and initial results of the Nutrition in Pregnancy and Growth in Southwest China (NPGSC) cohort. Pregnant women with their children in So...
Lyden, Grace R Barrett, Emily S Sathyanarayana, Sheela Bush, Nicole R Swan, Shanna H Nguyen, Ruby H N
Published in
Paediatric and perinatal epidemiology
Preconception life style and health play a pivotal role in positively impacting the health of a pregnancy, and this includes the reduction of exposure to endocrine-disrupting chemicals such as phthalates. We have previously demonstrated that women planning a pregnancy with assisted reproductive technology (ART) have lower phthalate metabolite conce...
Kloster, Stine Andersen, Anne-Marie Nybo Johnsen, Søren Paaske Nielsen, Dorte Guldbrand Ersbøll, Annette Kjaer Tolstrup, Janne S
Published in
Paediatric and perinatal epidemiology
Women with maternal congenital heart disease have a higher risk of preterm birth (PTB) and giving birth to a small for gestational age (SGA) infant. Advanced maternal age (≥35 years) likewise increases the risk of PTB and SGA, probably explained by poorer cardiovascular status. It is likely that advanced maternal age is particularly detrimental in ...
Bengtson, Angela M Phillips, Tamsin K le Roux, Stanzi M Brittain, Kirsty Zerbe, Allison Madlala, Hlengiwe Malaba, Thokozile Petro, Gregory Abrams, Elaine J Myer, Landon
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Published in
Paediatric and perinatal epidemiology
South Africa faces dual epidemics of HIV and obesity; however, little research has explored whether HIV status influences associations between pre-pregnancy body mass index (BMI) and adverse birth outcomes. To examine associations between pre-pregnancy body mass index (BMI) and adverse birth outcomes, and if they differ by HIV status. We followed H...
