Published in Paediatric and perinatal epidemiology
Large birth cohort studies are extremely valuable in assessing associations between early life exposures and long-term outcomes. Establishing new birth cohorts is challenging due to declining participation rates. Online methods of data collection may increase feasibility, but have not been evaluated thoroughly. The primary objective of the ongoing ...
Published in Paediatric and perinatal epidemiology
Personal and indoor air pollution monitors represent two ways to assess acute air pollution exposures; however, few reproductive epidemiology studies have incorporated these tools. To provide an overview of the unique challenges and opportunities that arise when measuring acute exposure to air pollution in two ongoing reproductive epidemiology stud...
Published in Paediatric and perinatal epidemiology
Lutenising hormone (LH) and human chorionic gonadotropin (hCG) hormone are useful biochemical markers to indicate ovulation and embryonic implantation, respectively. We explored "point-of-care" LH and hCG testing using a digital home-testing device in a cohort trying to conceive. To determine conception and spontaneous pregnancy loss rates, and to ...
Published in Paediatric and perinatal epidemiology
Antidepressant use later in pregnancy has been associated with preeclampsia and postpartum haemorrhage (PPH) in some studies. To evaluate the association between patterns of prenatal antidepressant dose across gestationand risk of precclampsia and PPH. We utilised OptumLabs® Data Warehouse (2012-2016) administrative health care claims, identifying ...
Published in Paediatric and perinatal epidemiology
Semen quality assessment in population-based epidemiologic studies presents logistical and financial challenges due to reliance on centralised laboratory semen analysis. The Trak Male Fertility Testing System is an FDA-cleared and validated at-home test for sperm concentration and semen volume, with a research use only sperm motility test. Here we ...
Published in Paediatric and perinatal epidemiology
Experiences typically considered private, such as, miscarriages and preterm births are being discussed publicly on social media and Internet discussion websites. These data can provide timely illustrations of how individuals discuss miscarriages and preterm births, as well as insights into the wellbeing of women who have experienced a miscarriage. ...
Published in Paediatric and perinatal epidemiology
Published in Paediatric and perinatal epidemiology
Using ICD-9 codes underestimates the prevalence of obesity in adults; however, the validity of these codes in studies of pregnancy-related outcomes is not known. To compare classification of maternal obesity based on ICD-9 codes in hospital discharge records versus data from birth certificates in the same women, examine predictors of agreement, and...
Published in Paediatric and perinatal epidemiology
Childhood liver cancers are relatively rare, hence inferences on incidence trends over time are limited by lack of precision in most studies. To conduct a systematic review and meta-analysis of published contemporary trends on childhood liver cancer incidence rates worldwide. PubMed, EMBASE, CINAHL, Web of Science. English-language peer-reviewed ar...
Published in Paediatric and perinatal epidemiology
Normal brain development is dependent on maternal, fetal and neonatal thyroid function. Measuring neonatal thyroid-stimulating hormone (TSH) 48-72 hours after birth screens for congenital hypothyroidism, allowing early treatment to avoid serious impairment. However, even within sub-clinical ranges, disrupted thyroid homeostasis during brain develop...
