Common Core Assessments in follow-up studies of adults born preterm-Recommendation of the Adults Born Preterm Internatio...
...Published in Paediatric and perinatal epidemiology
Of all newborns, 1%-2% are born very preterm (VP;
Sedentary behaviour and physical activity across pregnancy and birth outcomes.
Published in Paediatric and perinatal epidemiology
Shorter gestation or smaller birth size are indicators of a suboptimal fetal environment and negatively impact short- and long-term offspring health. Understanding how modifiable maternal behaviours, such as moderate-to-vigorous intensity physical activity (MVPA) or sedentary behaviour (SED), improve fetal outcomes could inform strategies to improv...
Post-partum interval and time to pregnancy in a prospective preconception cohort.
Published in Paediatric and perinatal epidemiology
Little is known about the influence of the post-partum interval-defined as the time between giving birth and attempting to conceive again-on subsequent fecundability. We evaluated the association between the post-partum interval and fecundability in Pregnancy Study Online (PRESTO), a web-based prospective preconception cohort of pregnancy planners ...
Disparities in neonatal abstinence syndrome and health insurance status: A statewide study using non-claims real-time su...
Published in Paediatric and perinatal epidemiology
Most studies examining the relationship between neonatal abstinence syndrome (NAS) and health insurance status in the United States (USA) have used administrative insurance claims data, which is subject to myriad limitations. We examined the association between NAS and health insurance status in a large geographically defined rural population in th...
Are paternal or grandmaternal age associated with higher probability of trisomy 21 in offspring? A population-based, mat...
Published in Paediatric and perinatal epidemiology
Fetal aneuploidy risk increases with maternal age, but the majority of pregnancies complicated by trisomy 21 occur in younger women. It has been suggested that grandmaternal and/or paternal age may also play a role. To assess the association between grandmaternal and paternal age and trisomy 21. For the grandmaternal assessments, we included all of...
Risk of non-syndromic orofacial clefts by maternal rural-urban residence and race/ethnicity: A population-based case-con...
Published in Paediatric and perinatal epidemiology
Orofacial clefts (OFC) have multifactorial aetiology. Established risk factors explain a small proportion of cases. To evaluate OFC risk by maternal rural residence and race/ethnicity, and test whether these associations changed after US-mandated folic acid fortification. This population-based case-control study included all non-syndromic OFC cases...
Maternal age at birth and neonatal mortality: Associations from 67 low-income and middle-income countries.
Published in Paediatric and perinatal epidemiology
Both young and advanced maternal age have been associated with higher risks of neonatal mortality, but most studies are from high-income countries and the evidence from low- and middle-income countries (LMICs) is scarce. To investigate the association between maternal age at delivery and neonatal mortality in LMICs. This is a cross-sectional study ...
Population-based study of serum ferritin in early pregnancy and adverse perinatal outcomes.
Published in Paediatric and perinatal epidemiology
Chronic placental inflammation is associated with preterm birth (PTB) and perinatal mortality. Ferritin is often elevated in chronic inflammatory conditions, but prior studies of its relation to PTB were restricted to ferritin measurement within pregnancy, were underpowered to detect rarer outcomes, and did not account for pre-existing maternal inf...
Quantification of selection bias in studies of risk factors for birth defects among livebirths.
...Published in Paediatric and perinatal epidemiology
Risk factors for birth defects are frequently investigated using data limited to liveborn infants. By conditioning on survival, results of such studies may be distorted by selection bias, also described as "livebirth bias." However, the implications of livebirth bias on risk estimation remain poorly understood. We sought to quantify livebirth bias ...
Maternal hypertensive disorders and subtypes of hypospadias: A Dutch case-control study.
Published in Paediatric and perinatal epidemiology
Hypospadias is a frequently occurring congenital anomaly in male infants, in which the opening of the urethra is located along the ventral side of the penis. Although various studies attempted to identify its causes, the aetiology of the majority of hypospadias cases remains poorly understood. Maternal hypertensive disorders are believed to be asso...
