King, Anthony J Hudson, Jemma Azuara-Blanco, Augusto Burr, Jennifer Kernohan, Ashleigh Homer, Tara Shabaninejad, Hosein Sparrow, John M Garway-Heath, David Barton, Keith
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Published in
Ophthalmology
To determine whether primary trabeculectomy or medical treatment produces better outcomes in terms of quality of life (QoL), clinical effectiveness, and safety in patients with advanced glaucoma. Multicenter randomized controlled trial. Between June 3, 2014, and May 31, 2017, 453 adults with newly diagnosed advanced open-angle glaucoma in at least ...
Rabiolo, Alessandro Triolo, Giacinto Khaliliyeh, Daniela Jin, Sang Wook Morales, Esteban Ghirardi, Alessandro Anand, Nitin Montesano, Giovanni Virgili, Gianni Caprioli, Joseph
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Published in
Ophthalmology
Review hypotony failure criteria used in glaucoma surgical outcome studies and evaluate their impact on success rates. Systematic literature review and application of hypotony failure criteria to 2 retrospective cohorts. A total of 934 eyes and 1765 eyes undergoing trabeculectomy and deep sclerectomy (DS) with a median follow-up of 41.4 and 45.4 mo...
Lidder, Alcina K Vanner, Elizabeth A Chang, Ta Chen Lum, Flora Rothman, Adam L
Published in
Ophthalmology
To evaluate risk factors for intraocular pressure (IOP) spike after cataract surgery using the IRIS® Registry (Intelligent Research in Sight). Retrospective clinical cohort study. Adults with IRIS Registry data who underwent stand-alone phacoemulsification from January 1, 2013, through September 30, 2019. Intraocular pressure spike was defined as p...
Shahraki, Kourosh Suh, Donny W
Published in
Ophthalmology
Kupersmith, Mark J Fraser, Clare L Morgenstern, Rachelle Miller, Neil R Levin, Leonard A Jette, Nathalie
Published in
Ophthalmology
We describe the baseline ophthalmic and cardiovascular risk factors across countries, race, and sex for the Quark207 treatment trial for acute nonarteritic anterior ischemic optic neuropathy (NAION). Prospective, randomized controlled clinical trial. Adults 50 to 80 years of age with acute NAION recruited from 80 sites across 8 countries. Ophthalmi...
Dai, Jinhui Yuan, Fei Wang, Jing
Published in
Ophthalmology
Sammons, Emily L Buck, Georgina Bowman, Louise J Stevens, William M Hammami, Imen Parish, Sarah Armitage, Jane
Published in
Ophthalmology
Preclinical studies support a protective role for aspirin in early diabetic retinopathy (DR), but the findings from randomized trials are limited. We present randomized evidence for the efficacy and safety of aspirin on DR outcomes. A substudy of the A Study of Cardiovascular Events in Diabetes (ASCEND) double-masked, randomized, placebo-controlled...
Panigrahi, Arnav Gupta, Viney Gupta, Shikha
Published in
Ophthalmology
Spencer, Sascha K R Ireland, Patrick A Braden, Jorja Hepschke, Jenny L Lin, Michael Zhang, Helen Channell, Jessie Razavi, Hessom Turner, Angus W Coroneo, Minas T
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Published in
Ophthalmology
This systematic review examined geographical and temporal trends in medical school ophthalmology education in relationship to course and student outcomes. Evidence suggesting a decline in ophthalmology teaching in medical schools is increasing, raising concern for the adequacy of eye knowledge across the rest of the medical profession. Systematic r...
Chauhan, Muhammad Z Elhusseiny, Abdelrahman M Kishor, Krishna S Sanvicente, Carina T Ali, Arsalan A Sallam, Ahmed B Bhattacharya, Sanjoy K Uwaydat, Sami H
Published in
Ophthalmology
To assess the correlation between primary open-angle glaucoma (POAG) and the risk of developing diabetic retinopathy (DR) in patients with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM). A retrospective cohort study leveraging the global patient database of TriNetX Research Network. The study included 44 359 patients with diabe...
