Published in Open forum infectious diseases
The COVID- 19 pandemic has showcased the field of Infectious Diseases (ID). We used Google Trends to find that this newfound attention has led to higher interest in ID training. © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America.
Published in Open forum infectious diseases
From an isolated epidemic, coronavirus disease 2019 has now emerged as a global pandemic. The availability of genomes in the public domain after the epidemic provides a unique opportunity to understand the evolution and spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus across the globe. We performed whole-genome sequencin...
Published in Open forum infectious diseases
The preventive effect that tenofovir/emtricitabine (FTC) could have against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human immunodeficiency virus-negative people is unknown. The objective of this study was to analyze the seroprevalence and clinical manifestations of COVID-19 among users of pre-exposure prophylaxis (PrEP), dis...
Published in Open forum infectious diseases
We identified deep diabetic foot infections by culture and conducted a case-control study examining the risk factors for moderate to severe methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa (PsA) diabetic foot infections. Our MRSA prevalence was lower than literature values; PsA was higher. Gangrene may be predictive of ...
Published in Open Forum Infectious Diseases
Background Despite increasing recognition of the importance of optimal antibiotic selection and expansion of antimicrobial stewardship activities to ambulatory settings, few studies have examined the frequency of parenteral antibiotic use among ambulatory children. We assessed the prevalence and patterns of parenteral antibiotic administration amon...
Published in Open Forum Infectious Diseases
Delivering all elements of HCV care at a single site accessible to opioid-dependent patients is accomplished with co-located HCV and methadone maintenance treatment. Embedded care unites expertise in HCV and addiction, yields high SVR rates and facilitates treatment of the transmitting population.
Published in Open Forum Infectious Diseases
Background The novel severe acute respiratory coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) originated in December 2019 and has now infected almost 5 million people in the United States. In the spring of 2020, private laboratories and some hospitals began antibody testing despite limited evidence-based guidance. Methods...
Published in Open forum infectious diseases
We describe a case of a 19-year-old female presenting with Mycobacterium bovis meningitis, a rarely encountered infection. We discuss the use of pyrosequencing to aid in prompt diagnosis of M. bovis infection, as well as treatment strategies and challenges given the organism's intrinsic resistance to pyrazinamide. © The Author(s) 2020. Published by...
Published in Open forum infectious diseases
We describe a 43-year-old patient with coronavirus disease 2019 who developed a bullous hemorrhagic rash that progressed to necrotic lesions. Histopathology confirmed a vasculitis of small- and medium-sized cutaneous vessels. © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America.
Published in Open Forum Infectious Diseases
Background Although widely accepted for adults, the safety of outpatient parenteral antimicrobial therapy (OPAT) in very old patients has not been examined. Methods Nonagenarians (age ≥90 years) discharged from the hospital on OPAT over a 5-year period were identified from the Cleveland Clinic OPAT Registry. Three matched controls (
