Collier, Tony Smith, Shievon Greenwood, Michelle Ng, Kenrick
Published in
Oncology and Therapy
This article is co-authored by a patient with metastatic hormone-sensitive prostate cancer who is receiving abiraterone and androgen deprivation therapy treatment in Manchester, UK. The patient relates his personal experiences struggling with the diagnosis, his experience with treatment and the physical, emotional and psychosexual impact on his lif...
de Las Heras, Begoña Saini, Kamal S Boyle, Frances Ades, Felipe de Azambuja, Evandro Bozovic-Spasojevic, Ivana Romano, Marco Capelan, Marta Prasad, Rajeev Pattu, Pugazhenthi
...
Published in
Oncology and therapy
The coronavirus disease-2019 (COVID-19) pandemic has had a significant impact on patients with underlying malignancy. In this article, we summarize emerging data related to patients with cancer and COVID-19. Among patients with COVID-19, a higher proportion have an underlying diagnosis of cancer than seen in the general population. Also, patients w...
Gordon-Craig, Sophie Parks, Ruth M. Cheung, Kwok-Leung
Published in
Oncology and Therapy
A move is under way towards personalised cancer treatment, where tumour biology of an individual patient is examined to give unique predictive and prognostic information. This is extremely important in the setting of older women, who have treatment-specific goals which may differ from their younger counterparts, and may include conservation of qual...
Rosas, Daniel Raez, Luis E.
Published in
Oncology and Therapy
Recent years has seen the discovery and description of genetic alterations responsible for oncogenesis in a wide variety of cancers, together with the finding that some markers are actionable and can be targeted by medications. Such developments have enabled cancer treatments to evolve from empirical palliative chemotherapy, with low chances of res...
Serra-Roma, André Shakhova, Olga
Published in
Oncology and Therapy
Neuroblastoma represents 8–10% of all childhood cancer cases and is responsible for 15% of all cancer-related deaths in infants. Even though patients with low- and intermediate-risk disease have a good prognosis, the 5-year survival rate of the vast majority of patients with high-risk neuroblastoma is 50%. Despite extensive research efforts to find...
Berardi, Rossana Mocchegiani, Federico Rinaldi, Silvia Fiordoliva, Ilaria Rovinelli, Francesca Caramanti, Miriam Federici, Alan Burattini, Michela Morgese, Francesca Torniai, Mariangela
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Published in
Oncology and Therapy
Introduction Biliary tract cancers (BTC) include both gallbladder cancer and cholangiocarcinoma, both of which have a poor prognosis. The aim of our study was to evaluate the main clinical prognostic factors in this setting and to assess their impact on overall survival (OS). Methods We retrospectively analyzed data collected on 64 patients with BT...
Tiruneh, Tegenaw Enawgaw, Bamlaku Shiferaw, Elias
Published in
Oncology and Therapy
Therapy-related myeloid neoplasms are a life-threatening and often fatal complication, associated with poor prognosis outcomes and with high-risk unfavorable cytogenetic abnormalities including complex karyotype. They occur after the treatment of primary malignancies using chemotherapy and/or radiation therapy. Such therapy is not specific to cance...
Mäkitie, Antti A. Devaney, Kenneth O. Baujat, Bertrand Almangush, Alhadi Ferlito, Alfio
Published in
Oncology and Therapy
Laryngeal sarcomas constitute an extremely rare entity among head and neck malignancies. Furthermore, most of them are chondrosarcomas, and the osteogenic form remains a true rarity. In general, there is a lack of information on the characteristics of laryngeal osteosarcoma. Thus, we sought to critically review the existing world literature on lary...
Morgese, Francesca Sampaolesi, Caterina Torniai, Mariangela Conti, Alessandro Ranallo, Nicoletta Giacchetti, Alfredo Serresi, Stefano Onofri, Azzurra Burattini, Michela Ricotti, Giuseppe
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Published in
Oncology and Therapy
Introduction Melanoma is one of the most common cancers in younger people. The incidence of cutaneous melanoma is increasing in patients of both sexes, with female patients generally living longer than their male counterparts. The aim of this retrospective study was to evaluate and confirm the sex-based difference in survival of melanoma patients a...
Fiorentini, Alessandro Capelli, Debora Saraceni, Francesco Menotti, Diego Poloni, Antonella Olivieri, Attilio
Published in
Oncology and Therapy
Acute myeloid leukemia (AML) is a complex disease characterized by genetic and clinical heterogeneity and high mortality. After 40 years during which the standard of care for patients evolved very little, the therapeutic landscape has recently seen rapid changes, with the approval of eight new drugs by the Food and Drug Administration (FDA) within ...
