Zhao, Yan Jiang, Haiyang Gu, Ming Zu, Cong Zheng, Xinyu
Published in
Oncology Letters
The development of drug resistance to chemotherapeutic agents has consistently presented a challenge in terms of the treatment of patients with triple-negative breast cancer (TNBC). In the present study, gemcitabine (dFdC)-resistant TNBC cells were established, and the effects of lentivirus-deoxyribonucleoside kinase (dNK) and a mutated form of dNK...
Sun, Rongxin Yang, Longyan Hu, Yangping Wang, Yan Zhang, Qiang Zhang, Yuanyuan Ji, Zhili Zhao, Dong
Published in
Oncology Letters
Differentiated thyroid cancer (DTC) is a common type of cancer among women with an increasing worldwide incidence rate. However, there are no specific and sensitive molecular biomarkers for DTC diagnosis or prognosis. Angiopoietin-like protein 1 (ANGPTL1) may be a novel tumor suppressor in lung, breast, colorectal and hepatocellular carcinoma. Howe...
You, Huizeng Wang, Shuyong Yu, Sa
Published in
Oncology Letters
Long non-coding RNAs (lncRNAs) have been reported to serve a crucial role in the progression of nasopharyngeal carcinoma (NPC); however, the underlying molecular mechanisms of lncRNA KIF9-AS1 in the tumorigenesis of NPC remains poorly understood. Reverse transcription-quantitative PCR was used to analyze the expression levels of KIF9-AS1 and microR...
Wu, Qing Feng, Qiong Xiong, Yanfei Liu, Xing
Published in
Oncology Letters
Ras-related protein Rab-31 (RAB31), a small guanosine 5′-triphosphate-binding protein, is a member of the Rab family and has been demonstrated to serve an oncogenic role in several common types of human cancer. However, the function of RAB31 in osteosarcoma (OS) has not been previously studied. The present study identified that the expression level...
Cho, Hyungwoo Kim, Jeong Eun Kim, Sun Young Kim, Kyu-Pyo Kim, Tae Won Park, Jin-Hong Kim, Jong Hoon Lim, Seok-Byung Yu, Chang Sik Kim, Jin Cheon
...
Published in
Oncology Letters
The present study aimed to compare the pattern of distant recurrence between patients with non-metastatic rectal cancer treated with pre-operative (OP) and those treated with post-operative (post-OP) chemoradiotherapy (CRT). A total of 631 patients with newly diagnosed non-metastatic rectal cancer who had received pre-OP or post-OP CRT with curativ...
Li, Xiaohui Song, Feifei Sun, Hongqiang
Published in
Oncology Letters
The long non-coding (lnc)RNA associated with poor prognosis of hepatocellular carcinoma (AWPPH) serves as an oncogene in several cancers, such as liver and bladder cancers, however, to the best of our knowledge, its function in T-cell acute lymphoblastic leukemia is unknown. The results of the present study revealed that the expression levels of ln...
Wang, Shuyong You, Huizeng Yu, Sa
Published in
Oncology Letters
Nasopharyngeal carcinoma (NPC) is a rare malignancy arising from the nasopharyngeal epithelium and belongs to the group of head and neck cancer types, which are usually associated with viral and/or environmental influences, as well as heredity causes. A recent study reported that the long non-coding RNA (lncRNA) HOXA cluster antisense RNA 2 (HOXA-A...
Lin, Ying Zhong, Hongbin Sun, Baicheng Peng, Yongtiao Lu, Fuhua Chen, Miaoxuan Zhu, Maoshu Huang, Jiyi
Published in
Oncology Letters
Renal cell carcinoma (RCC) is one of the commonest urological tumors. The incidence of RCC ranks third among urological tumors, after prostate cancer and bladder tumors. However, the etiology of RCC remains unclear. Ubiquitin-specific protease 22 (USP22), a potential marker of cancer stem cells, is associated with the occurrence and progression of ...
Wen, Xueyan Li, Songrong Guo, Mengchan Liao, Hongzhan Chen, Yongmin Kuang, Xi Liao, Xiaoping Ma, Lin Li, Qifu
Published in
Oncology Letters
Glioblastoma (GBM) is the most common malignant primary tumor in the human central nervous system. The present study aimed to explore the molecular mechanism by which microRNA (miR)-181a-5p targets the F-box protein 11 (FBXO11) in glioma cells to inhibit cell proliferation and invasion. Reverse transcription-quantitative (RT-q)PCR was performed to ...
Zhang, Xiao-Ying Zhang, Pei-Ying
Published in
Oncology Letters
