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Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish.

Published in Journal of applied toxicology : JAT

Cardiovascular toxicity is a major challenge for the pharmaceutical industry and predictive screening models to identify and eliminate pharmaceuticals with the potential to cause cardiovascular toxicity in humans are urgently needed. In this study, taking advantage of the transparency of larval zebrafish, Danio rerio, we assessed cardiovascular tox...

Chronic ambient hydrogen sulfide exposure and cognitive function

Published in Neurotoxicology and Teratology

Effects of tobacco smoke on PC12 cell neurodifferentiation are distinct from those of nicotine or benzo[a]pyrene

Published in Neurotoxicology and Teratology

Negative confounding by essential fatty acids in methylmercury neurotoxicity associations

Published in Neurotoxicology and Teratology

Cognitive and biochemical effects of monosodium glutamate and aspartame, administered individually and in combination in...

Published in Neurotoxicology and Teratology

•Monosodium glutamate (MSG) and Aspartame (ASM) are tested for toxicity in male rats.•MSG and ASM individually and jointly disrupt cognitive capabilities.•These cognitive behaviors are controlled by hippocampus and striatum (in forebrain).•MSG and ASM jointly affect neurotransmitters and oxidative stress in forebrain.•MSG and ASM are more neurotoxi...

Neurotoxicity from prenatal and postnatal exposure to methylmercury

Published in Neurotoxicology and Teratology

Prenatal methamphetamine exposure and neurodevelopmental outcomes in children from 1 to 3years

Published in Neurotoxicology and Teratology

Neurophysiological assessment of auditory, peripheral nerve, somatosensory, and visual system functions after developmen...

Published in Neurotoxicology and Teratology

Ivermectin reduces sexual behavior in female rats

Published in Neurotoxicology and Teratology

•Effects of ivermectin (IVER) were studied on sexual behavior of female rats in estrus or induced by estrogen.•The lordosis quotient and the lordosis intensity were measured.•IVER high dose reduced the lordosis quotient in hormone-induced sexual behavior but not in female observed in estrus phase.•IVER decreased the sexual behavior intensity in bot...

Neurotoxicity from prenatal and postnatal exposure to methylmercury

Published in Neurotoxicology and Teratology

•Prenatal exposure to methylmercury is known to cause a neurotoxicity risk•Lower postnatal exposure is of uncertain risk and correlates with prenatal exposure•Mutual adjustment of error-prone exposure variables appears inappropriate•Postnatal visuospatial deficits are suggested by structural equation modeling